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教育及工作背景EDUCATIONANDWORKBACKGROUND 2017.01-2019.01天津大学仪器科学与技术博士后 2014.06-今天津工业大学生物医学工程专业系主任 2011.08-2013.08JohnsHopkinsUniversityBMEDepartment国家公派访问学者 2008.09-2014.06天津大学精密仪器与光电子工程学院生物医学工程博士 2004.09-2008.07天津大学精密仪器与光电子工程学院生物医学工程学士 2005.09-2008.07南开大学国际金融学(学士双学位) 项目经历PROJECTEXPERIENCE 2014.07-今天津市医学电子诊疗工程技术中心 可穿戴医疗设备研发、超光谱成像应用 2010.09-2013.08LaboratoryofBiophotonicsImagingandTherapy,JohnsHopkinsUniversity,USA 分子荧光断层层析成像(FMT)、光学层析成像(OCT):FMT系统搭建、散射模型的建立、仿真以及断层重建算法,实现对小鼠体内荧光物质浓度分布三维重建;SS-OCT系统设计。 2008.09-2010.08生物医学信号分析与处理天津市重点实验室,天津大学 参与国家自然科学基金《血液成分无创检测的动态光谱理论与方法》的研究:检测方法的创新、检测仪器的设计、临床试验、数据挖掘分析等。 2008.09-2010.08测量与控制工程国家重点实验室,天津大学 参与国家自然科学基金《基于高谱图的中医舌诊规范化》研究:舌诊采集设备的搭建和数据建模分析等。 基金项目 1.天津市科委重点项目11JCZDC17100基于动态光谱的血液成分无创分析仪器20万2011-04至2014-03第二名(结题) 2.国家自然科学基金60674111血液成分无创检测的动态光谱理论与方法的研究28万2007-01至2009-12参与(结题) 3.国家自然科学基金30973964基于高光谱的中医舌诊规范化31万2010-01至2012-12参与(结题) 4.内蒙古自治区科技计划项目基于物联网技术的智能健康监控及现代医疗信息系统研发100万2016-2019年天津工业大学负责人 5.国家纳米科学中心中科院纳米生物效应与安全性重点实验室开放课题NSKF201602多光谱荧光分子断层成像方法研究2万2016-2017年负责人 6.中国博士后科学基金会61批面上多光谱信息融合的荧光分子断层成像方法研究5万2017-2019负责人 7.天津市互联网跨界融合专项基于互联网+的心血管健康管理服务系统研发与应用50万2018-2021第二负责人 8.家用正压通气呼吸治疗机关键技术及样机研发天津市企业科技特派员项目5万18JCTPJC592002018-2021 9.智能化闭环自动心肺复苏反馈辨识-优化协调-协同控制关键技术与装备研究天津市军民融合重点项目75万2018-2021天津工业大学负责人 10.基于深度学习和多光谱融合的荧光分子断层成像肿瘤检测方法研究,6万,天津市自然科学基金2019-2021,负责人 11.基于磁、声刺激的脑力疲劳缓解关键技术及可穿戴设备研发,5万,天津市科技特派员项目,2019-2021,负责人 12面向肝癌精准检测的多光谱荧光分子断层重建关键技术研究,22万,国家自然科学基金,2020-2022,负责81901789 13.亚毫米尺寸阵列式微磁刺激装置设计及其对海马区Schaffer-CAI突触可塑性调控机理的研究,2019.1-2019.12,第二,16万 发明专利: 1.2009.02.25磁性药物引导系统.ZL200710057046.7,李刚,赵喆,王慧泉. 2.2010.04.22散射物质多维光谱测量装置与方法,ZL201010152294.1,李刚,赵喆,林凌,王慧泉 3.2015.03.20一种使用多模式连续血压测量装置的自标定方法,ZL201510125529.0,王慧泉,乌维磊,庞志祥 4.2015.08.12.一种多模式连续血压测量装置,ZL20152016910.3,王慧泉、乌维磊、庞志祥 5.2013.2.08一种医用腔道内容物目标成分回收器械,201310051614.8,张发明,王慧泉,姚怡昕 6.2018.8.07,一种用于测量物质光学参数的漫射光子密度波系统,ZL201720520849.0,王慧泉、何鑫伟、缪竟鸿、王金海、赵喆 软件著作权: 1.光学参数测量系统,天津工业大学,2015SR256113 2.光学断层成像软件,天津工业大学,2015SR254949 3.荧光断层数据重建软件,天津工业大学,2015SR25589 4.生物体异质体快速检测系统V1.0,天津工业大学,2017SR532846 5.光学参数测量系统控制软件V1.0,天津工业大学,2017SR532322 获奖情况SCHOLARSHIPANDAWARDS: 2018年获天津市科学进步二等奖 2018年获中国产学研合作创新(个人)奖 2018年获中国产学研合作项目成果一等奖 2013年获“TheNewVentureCompetition”美中创新创业竞赛第二名(美国) 2012年获中国科技创业计划大赛“海创新秀奖”(Top20/2000) 2011年获天津市“创新奖学金”一等奖 校内外工作经历WORKEXPERIENCE: 2013年美国Baltimore华人专家学者联合会创始人之一、主席 2014年-今天津工业大学电子与信息工程学院生物医学工程系主任 2015年-今中国医疗保健国际交流促进会健康保障分会青年理事 2015-2017年江苏省“企业创新岗”特聘专家(科技副总) 2017年-今安全防范技术与评估公安部重点实验室特聘研究员 2018年-今中国人民大学卫生技术评估与医药政策研究中心委员 2019年-今中国医学装备协会教育培训分会常委

研究领域

可穿戴医疗设备、近红外光谱分析、数据挖掘、生物医学信号分析与处理、分子生物学(联合培养方向)

近期论文

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1.李刚,王慧泉,赵喆,等.动态光谱数据质量评价标准.光谱学与光谱分析,2010,30(10):2802-2806.(SCI:668KP)(EI:20104313323545) LiGang,WangHuiquan,ZhaoZhe,etal.Thequalityevaluationofthedynamicspectrumdata.SpectroscopyandSpectralAnalysis,2010,3(10):2802-2806. 2.李刚,王慧泉,赵喆,等.利用谐波分量提高预测精度.光谱学与光谱分析,2010,30(9):2385-2389.(SCI:648AA)(EI:20103713225942) LiGang,WangHuiquan,ZhaoZhe,etal.Increasetheprecisionofthenon-invasivebloodcomponentsmeasurementbasedonDSmethodusingHarmonicWaves.SpectroscopyandSpectralAnalysis,2010,30(9):2385-2389. 3.HuiquanWang,GangLi,ZheZhao,etal.DynamicspectrumandBPneuralnetworkfornon-invasivehemoglobinmeasurement.LifeSystemModelingandIntelligentComputingLectureNotesinComputerScience,2010,Volume6330,67-74.(SCI:BUI52)(EI:20104913448368) 4.HuiquanWang,GangLi,ZheZhao,etal.Non-invasivemeasurementofhemoglobinbasedondynamicspectrummethod.TransactionsoftheInstituteofMeasurementandControl,2011,35(1).(SCI:134AV)(EI:20130716028314) 5.李刚,王慧泉,张昊,等.无创血液成分检测全波段信号信噪比均衡.光谱学与光谱分析,2012,32(2):486-490.(SCI:883BB)(EI:20120714766758) LiGang,WangHuiquan,ZhangHao,etal.Theequalizationofwhole-bandsignal’sSNRinthebloodcomponentsnoninvasivemeasurement.SpectroscopyandSpectralAnalysis,2012,32(2):486-490. 6.李刚,王慧泉,赵喆,等.提高DS法无创血液成分检测信噪比的方法与分析.光谱学与光谱分析,2012,32(8):2290-2294.(SCI:983NW)(EI:20123715424465) LiGang,WangHuiquan,ZhaoZhe,etal.TheanalysisforimprovingtheSNRofbloodcomponentsnoninvasivemeasurementwithDSmethod.SpectroscopyandSpectralAnalysis,2012,32(8):2290-2294. 7.李刚,赵喆,刘蕊,王慧泉,等.利用多光程长光谱法检测血液多种成分含量的研究.光谱学与光谱分析,2010,30(9):2381-2384.(SCI:648AA)(EI:20103713225941) LiGang,ZhaoZhe,LiuRui,WangHuiquan,etal.Researchonthebloodcomponentsdetectingbymulti-opticalpathlengthspectroscopytechnique.SpectroscopyandSpectralAnalysis,2011,30(9):2381-2384. 8.李刚,赵喆,刘蕊,王慧泉,等.尿微量白蛋白的多波段多光程光谱检测,分析化学.2011,39(4):588-591.(SCI:786ZE) LiGang,ZhaoZhe,LiuRui,WangHuiquan,etal.Urinaryalbumindetectedbymulti-bandmulti-opticalpathlengthspectroscopytechnique.ChineseJournalofAnalyticalChemistry.2011,39(4):588-591. 9.李刚,门剑龙,孙兆敏,王慧泉,等.动态光谱用于人体血液中多种蛋白的无创测量.天大学报,2011,14(1):90-94.(EI:20111013735369) LiGang,MenJian-long,SunZhao-min,WangHuiquan,etal.Non-invasivemeasurementofhumanbloodproteinconcentrationbasedondynamicspectrummethod.TransactionsofTianjinUniversity,2011,14(1):90-94. 10.李刚,门剑龙,孙兆敏,王慧泉,等.小波变换提高动态光谱法血液成分无创检测的精度.光谱学与光谱分析,2011,31(2):469-472.(SCI:729XH)(EI:20111013723742) LiGang,SunZhaomin,WangHuiquan,etal.Applicationofwavelettransformonimprovingdetectingprecisionofthenon-invasivebloodcomponentsmeasurementbasedondynamicspectrummethod.SpectroscopyandSpectralAnalysis,2011,31(2):469-472. 11.林凌,吴晓爽,王慧泉,等.过采样提高等效分辨率.电子设计工程,2011,18(8):48-51. LinLing,WuXiaoshuang,WangHuiquan,etal.Digitalfront-endinthesoftwaredefinedinstrumentandtheequivalentresolutionofADC.ElectronicDesignEngineering,2011,18(8):48-51. 12.李刚,熊婵,王慧泉,等.动态光谱的单拍提取.光谱学与光谱分析,2011,31(7):1857-1861.(SCI:790GD)(EI:20112814137331) LiGang,XiongChan,WangHuiquan,etal.Single-TrialEstimationofDynamicSpectrum.Spectroscopyandspectralanalysis.SpectroscopyandSpectralAnalysis,2011,31(7):1857-1861. 13.李刚,赵喆,刘蕊,王慧泉,等.尿微量白蛋白的可见-近红外光谱检测.光谱学光谱分析,2011,31(9):2412-2415.(SCI:819AH)(EI:20113714322983) LiGang,ZhaoZhe,LiuRui,WangHuiquan,etal.ResearchonTheMeasurementofUrinaryAlbuminbyVisible-nearInfraredSpectroscopy.Spectroscopyandspectralanalysis,2011,31(9):2412-2415. 14.WenfeiLiu,GuiliLiu,XiaofeiWang,YanfeiBao,GangLi,HuiquanWang.Non-invasivemeasurementstudyofhumanbloodalcoholconcentrationbasedonNIRdynamicspectrum.ImageAnalysisandSignalProcessing(IASP),2011InternationalConferenceon,pp.492-495,Oct.2011.(EI:20120414709760) 15.索永宽,李刚,王慧泉,等.基于动态光谱法的人体血液胆固醇含量无创检测.光谱学光谱分析,2012,32(1):188-191.(SCI:873RI)(EI:20120214676657) SuoYongkuan,LiGang,WangHuiquan,etal.Non-InvasiveMeasurementofHumanBloodCholesterolConcentrationBasedonDynamicSpectrumMethod.SpectroscopyandSpectralAnalysis,2012,32(1):188-191. 16.李刚,赵喆,王慧泉,等.复杂液体光谱法分析的浓度分辨率及浓度分布影响.光谱学光谱分析,2012,32(4):1077-1080.(SCI:921AI)(EI:20121514940827) LiGang,ZhaoZhe,WangHuiquan,etal.TheconcentrationresolutionofcomplexliquidspectrometryanalysisandtheeffectofconcentrationdistributionSpectroscopyandSpectralAnalysis,2012,32(4):1077-1080. 17.李刚,赵喆,王慧泉,等.浓度分布对光谱法检测成分含量精度的影响.光谱学光谱分析,2012,32(7):1905-1908.(SCI:987PN)(EI:20123215308552) LiGang,ZhaoZhe,WangHuiquan,etal.Effectofdifferentdistributionofcomponentsconcentrationontheaccuracyofquantitativespectralanalysis.SpectroscopyandSpectralAnalysis,2012,32(7):1905-1908. 18.李刚,赵喆,王慧泉,等.光谱仪器信噪比与建模波长数对光谱分析精度的影响.光谱学光谱分析,2012,32(8):2286-2289.(SCI:983NW)(EI:20123715424464) LiGang,ZhaoZhe,WangHuiquan,etal.Theeffectsofsignaltonoiseratioofinstrumentandnumberofwavelengthstotheaccuracyofspectralanalysis.SpectroscopyandSpectralAnalysis,2012,32(8):2286-2289. 19.李刚,周梅,王慧泉,等.动态光谱提取方法的对比研究.光谱学与光谱分析,2012,32(5):1324-1328.(SCI:940NK)(EI:20122615178928) LiGang,ZhouMei,WangHuiquan,etal.Contrastivestudyondynamicspectrumextractionmethod.SpectroscopyandSpectralAnalysis,2012,32(5):1324-1328. 20.GaoF,EddenRA,LiM,PutsNA,WangG,LiuC,ZhaoB,WangH,BaiX,ZhaoC,WangX,BarkerPB.Editedmagneticresonancespectroscopydetectsanage-relateddeclineinbrainGABAlevels.Neuroimage,2013,78C:75-82.(IF=5.895)(SCI:165MV) 21.CuiB.,LiP.,XuL.,PengZ.,ZhaoY.,WangH.,etal.Fecalmicrobiotatransplantationisaneffectiverescuetherapyforrefractoryinflammatoryboweldisease.PediatricAllergyPrinciples&Practice,2015,2(1),41-53.(SCI,EI) 22.CuiB.,LiP.,XuL.,ZhaoY.,WangH.,PengZ.,etal.Step-upfecalmicrobiotatransplantationstrategy:apilotstudyforsteroid-dependentulcerativecolitis.JournalofTranslationalMedicine,2015,13(1),298.(SCI,EI) 23.ZhengB.,GongX.,WangH.,WangS.,WangH.,LiW.,etal.Anir-remotecontrolledupconvertingnanoparticle:animprovedtoolforlivingcelldye-labeling.Nanotechnology,2015,26(42),425102.(SCI:000363433800003,二区,IF:3.404)(EI:20154701599540) 24.YanL.,WangH.,ZhangA.,ZhaoC.,ChenY.,&LiX.Brightandstablenear-infraredPluronic-silicananoparticlesascontrastagentsforinvivoopticalimaging.JournalofMaterialsChemistryB,2016,4(33):5560-5566.(SCI:000382016600007,一区,IF:4.776)(EI:20182505355065) 25.JinhaiWang,DongyuanLiu,YanjunZhang,WangHuiquan*,etal.ThestudyonincreasingtheequivalentSNRinthecertainDOIbyadjustingtheSDseparationinnear-infraredbrainimaging.InternationalSymposiumonOptoelectronicTechnologyandApplication2016:101572P.(SCI:000391228600095)(EI:20170503310140) 26.ImageReconstructionInRespiratoryMonitoringBasedontheAnatomicalInformationforMagneticDetectionElectricalImpedanceTomography.2016,13thIEEEInternationalConferenceonSignalProcessing(SCI,EI) 27.王慧泉,尹剑利,李光旭,冯彦博,王金海,&陈瑞娟.磁探测电阻抗成像呼吸监测仿真研究.生物医学工程学杂志,2017(1):27-33.(EI:20171303498019) HuiquanWang,JianliYin,GuangxuLi,YanboFeng.ImageReconstructionInRespiratoryMonitoringBasedontheAnatomicalInformationforMagneticDetectionElectricalImpedanceTomography.2017,33(1):27:33.(EI:20171303498019) 28.HuiquanWang,PengfeiHu,YuZheng,ZheZhao,BinZheng,JinChang,HanjieWang*,JinhaiWang*,ConstructionofICGencapsulatedW18O49@MSNasafluorescencecarrierforreal-timetrackedphotothermaltherapy,MaterialsScienceandEngineering:C,2017,80(1):102~109(SCI:000410254400013,一区,IF:5.08) 29.HuiquanWang,LinaRen,ZheZhao*,JinhaiWang*,HongliChen,Thestudyonfastlocalizationmethodofanomalyblockinbrainbasedondifferentialopticaldensity,Proc.SPIE10484,AdvancedBiomedicalandClinicalDiagnosticandSurgicalGuidanceSystemsXVI,SanFrancisco,California,2018.1.30-2018.2.4.(EI:20182005202835) 30.HuiquanWang,HaojieZhu,ZheZhao*,YanfengZhao,JinhaiWang*,TheIncreasingofDiscriminationAccuracyofWaxedApplesBasedonHyperspectralImagingOptimizedbySpectralCorrelationAnalysis,ArtificialIntelligenceandRobotics,2017.10.4-2017.10.5.(EI) 31.HuiquanWang,YanboFeng,JinhaiWang,HaofengQi,ZheZhao*,RuijuanChen*,TheResearchontheLungTumorImagingBasedontheElectricalImpedanceTomography,ArtificialIntelligenceandRobotics,2017.10.5.(EI) 32.王金海,刘东远,王慧泉*,张彦军,孙秋明,马军.多通道差分吸光度用于颅内血肿快速检测.光谱学与光谱分析,2018,38(10):3205-3209.(SCI:000449902800037,四区,IF:0.326) WANGJin-hai,LIUDong-yuan,WANGHui-quan,ZHANGYan-jun,SUNQiu-ming,MAJun.ApplicationofMulti-ChannelDifferentialOpticalDensityontheFastDeterminationoftheIntracranialHematomasDegree.SpectroscopyandSpectralAnalysis,2018,38(10):3205-3209.(EI:20184906178441) 33.张彦军,孙秋明,王慧泉,赵喆,孙景工,马军,刘东远.VIP分析简化近红外光硬膜血肿检测的研究.光谱学与光谱分析,2018,38(6):1691-1695.(SCI:000435531000007,四区,IF:0.326)(EI:20184205947911) YanjunZhang,QiumingSun,HuiquanWang,ZheZhao,etal.VIPanalysistosimplifytheNIRdetectionstudyoftheduralhematoma.SpectroscopyandSpectralAnalysis,2018,38(6):1691-1695. 34.SunQ.,ZhangY.,MaJ.,TianF.,WangH.,&LiuD,etal.Detectorlocationselectionbasedonvipanalysisinnear-infrareddetectionofduralhematoma.SaudiJBiolSci,2018,25(3),452-456.(SCI:000427071500008,一区,IF:3.138) 35.王慧泉,任丽娜,赵喆,王金海*,基于差分光密度差异的组织内异质体的快速定位方法,光谱学光谱分析,2018,38(11):3362-3367.(SCI:000452247200007,四区,IF:0.326)(EI:20190806521474) HuiquanWang,LinaRen,ZheZhao,JinhaiWang*,Thestudyoffastlocalizationmethodofanomalyblockintissuebasedondifferentialopticaldensity,SpectroscopyandSpectralAnalysis,2018,38(11):3362-3367. 36.HuiquanWang,LinaRen,ZheZhao,JinhaiWang*,HongliChen.FastLocalizationMethodofAnomalyinTissueBasedonDifferentialOpticalDensity.BiomedicalOpticalExpress,2018,9(5):2028-2026(SCI:000431181700001,二区,IF:3.482)(EI:20190806521474) 37.HuiquanWang,HaojieZhu,ZheZhao*,YanfengZhao,JinhaiWang.Thestudyonincreasingtheidentificationaccuracyofwaxedapplesbyhyperspectralimagingtechnology,MultimediaToolsandApplications,2018,70(20):27505-27516.(SCI:000444201500057,三区,IF:1.541)(EI:20181905148100) 38.HuiquanWang,FengXing,BoyaShi,WenxuanLiang,YongpingChen,JinhaiWang,XingdeLi.Signal-to-noiseratioanalysisandimprovementforfluorescencetomographyimaging.ReviewofScientificInstruments,89(9),2018(SCI:000446159100028,三区,IF:1.428)(EI:20184005899548) 39.HuiquanWang,WangHui,ZheZhao*,JinghongMiao*,JinhaiWang..Theinfluenceofspectralcharacteristicsontheaccuracyofconcentrationquantitativelyanalysisbynearinfraredspectroscopy,InfraredPhysics&Technology,2018,94:96-101.(SCI:000449130100015,二区,IF:1.851)(EI:20183705808778) Huiquan,W.,Hui,W.,Zhe,Z.,Jinghong,M.,&Jinhai,W..(2018).Theinfluenceofspectralcharacteristicsontheaccuracyofconcentrationquantitativelyanalysisbynearinfraredspectroscopy.InfraredPhysics&Technology,S1350449518304456-. 40.YuyuWang,GangLi,HuiquanWang,MeiZhou&LingLin.DynamicSpectrumfornoninvasivebloodcomponentanalysisanditsadvances,AppliedSpectroscopyReviews,2018,DOI:10.1080/05704928.2018.1509344.(SCI二区,TOP) 41.陈瑞娟,戚昊峰,李炳南,王慧泉*,王金海.基于栈式自编码器的磁探测电阻抗成像算法研究.仪器仪表学报,2019,40(1):44-51. RuijuanChen,HaofengQi,BingnanLi,HuiquanWang*,JinhaiWang.Studyonmagneticdetectionelectricalimpedancetomographyalgorithmbasedonstackedauto-encoder.ChineseJournalofScientificInstrument,2019,40(1):44-51.(EI:20191906900248) 42.HuiquanWang,FangXia,ZheZhao,XinweiHe,Jinhaiwang.OpticalParametersoftissuephantommeasurementbasedonDPDWwithmulti-frequencymodulation.(EI会议) 43.赵喆,王慧,王慧泉,何鑫伟,缪竟鸿,王金海.近红外光谱谱线特性对物质浓度分析误差影响的研究.光谱学与光谱分析.2019,39(4):1070-1074. 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