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个人简介

钟国富(Guofu Zhong),男,1962年出生,博士,教授,博士研究生导师,教育部长江学者特聘教授,浙江省“钱江学者”特聘教授。杭州市创新药物研究重中之重实验室负责人,杭州市重点学科药物化学负责人,新加坡催化科学学会创会执行委员。1983年毕业于南京理工大学获工学学士学位,1986年在上海华东理工大学获工学硕士学位并留校工作,1990年赴瑞士洛桑大学有机化学研究所师从Manfred Schlosser教授攻读博士学位,进行金属有机化学方面的研究。1995年离开瑞士加入美国著名的Scripps研究所(The Scripps Research Institute)随所长、美国科学院院士Richard A. Lerner教授做博士后研究,并于1998年初取得Scripps有机化学博士学位。1999年升为助理教授(Assistant Professor),进行催化抗体和有机催化方面的研究工作。2004年入选教育部长江学者特聘教授,于2005年初从Scripps全职回国加盟复旦大学化学系,同时受聘复旦大学生物医学研究院杰出PI。2006年受邀加入新加坡南洋理工大学化学与生化系,为该系初创老师之一。在南洋理工大学进行不对称催化方面的研究。2011年底应邀加入杭州师范大学工作至今 获奖情况 1. 南方科大化学科学讲座奖, 2017年 2. Wiley Excellent Paper Award , 2015年 3. Asian Core Program Lectureship Award , 2013年 4. 浙江省钱江学者特聘教授, 2013年 5. 新加坡总统科学奖提名, 2011年 6. 上海浦江人才(A类),2005年 7. 教育部长江学者奖励计划, 2004年

研究领域

主要从事有机化学、不对称催化和药物化学等方面的研究

近期论文

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Acylsilane directed aromatic C-H alkenylations by ruthenium catalysis, Xiunan Lu, Cong Shen, Keke Meng, Li Zhao,* Tingyan Li, Yalin Sun, Jian Zhang,* and Guofu Zhong,* Chem. Commun., 2019, 55, 826-829. Palladium catalyzed controllable mono- or di-allylic substitution reaction of benzothiazolylacetate with allylic alcohols, Peipei Yan, Shulei Pan, Jinjin Hu, Limei Lu, Xiaofei Zeng,* and Guofu Zhong,* Adv. Synth. Catal., 2019, 361, 1322-1334. Indium-mediated synthesis of benzylic hydroperoxides, Yuxuan Hou, Jinjin Hu, Ruigang Xu, Shulei Pan, Xiaofei Zeng,* and Guofu Zhong,* Org. Lett. 2019, 21, 4428-4432. Additive- and ligand-free cross-coupling reactions between alkenes and alkynes by iridium catalysis, Yaling Sun, Keke Meng, Jian Zhang,* Mengxin Jin, Nini Huang, and Guofu Zhong,* Org. Lett., 2019, 21, 4868-4872. Chiral phosphoric acid catalyzed enantioselective N-alkylation of indoles with in situ generated cyclic N-acyl ketimines, Lvye Zhang, Binqiang Wu, Zhangtao Chen, Jinjin Hu, Xiaofei Zeng,* and Guofu Zhong,* Chem. Commun., 2018, 54, 9230-9233. N-Heterocyclic carbene-catalyzed asymmetric benzoin reaction in water, Jun Yan, Rong Sun, Kuangxi Shi, Kai Li, Limin Yang,* and Guofu Zhong,* J. Org. Chem., 2018, 83, 7547-7552. NHC-catalyzed [4+2] cycloaddition reactions for the synthesis of 30-spirocyclic oxindoles via a C–F bond cleavage protocol, Jun Yan, Kuangxi Shi, Chengtao Zhao, Liyuan Ding, Shengsheng Jiang, Limin Yang,* and Guofu Zhong,* Chem. Commun., 2018, 54, 1567-1570. Chiral NHC-catalyzed 1,3-dipolar [3+2] cycloaddition of azomethine imines with α-chloroaldehydes for the synthesis of bicyclic pyrazolidinones, Limin Yang,* Yunbo Lv, Fei Wang, and Guofu Zhong,* Org. Biomol. Chem., 2018, 16, 4433-4438. A metal-free synthesis of 3-phenoxyimidazo heterocycles by catalytic oxidative cyclization of 2-amino-azaarenes with lignin models, Yizhou Chen, Shanlu Wang, Li Zhao,* Chenyan Rong,Tong Liu, Han Sun, Yuping Wang, Jian Zhang,* Guofu Zhong,* Synthesis, 2018, 50, A-H. Enantioselective dearomatization of naphthol derivatives with allylic alcohols by cooperative iridium and Brønsted acid catalysis, Dan Shen, Qiliang Chen, Peipei Yan, Xiaofei Zeng,* and Guofu Zhong,* Angew. Chem. Int. Ed., 2017, 56, 3242-3246. Synthesis of cyano-containing phenanthridine derivatives via catalyst-, base-, and oxidant-free direct cyanoalkylarylation of isocyanides, Weihong Song, Peipei Yan, Dan Shen, Zhangtao Chen, Xiaofei Zeng,* and Guofu Zhong,* J. Org. Chem., 2017, 82, 4444-4448. A direct cross-coupling reaction of electron-deficient alkenes using an oxidizing directing group, Chunbing Yu, Feifei Li, Jian Zhang,* and Guofu Zhong,* Chem. Commun., 2017, 53, 533-536. One step synthesis of c-alkylidenebutenolides from simple vinyl carboxylic acids and alkenes, Chunbing Yu, Jian Zhang,* and Guofu Zhong,* Chem. Commun., 2017, 53, 9902-9905. Ruthenium-catalyzed olefinic C–H alkenylation of enol-carbamates: highly stereo-selective synthesis of (Z,Z) and (Z,E)-butadienes, Tingyan Li, Jian Zhang,* Chunbing Yu, Xiunan Lu, Liqing Xu, and Guofu Zhong,* Chem. Commun., 2017, 53, 12926-12929. Copper-catalyzed oxidative cyclization of 2-amino-azaarenes with lignin models: synthesis of 3-phenoxy imidazo heterocycles, Jian Zhang,* Xiunan Lu, Tingyan Li, Shanlu Wang, and Guofu Zhong,* J. Org. Chem., 2017, 82, 5222-5229. Synthetic access to oxazolidin-4-ones via elimination/[3+2] cycloaddition reaction, Shengsheng Jiang, Kai Li, Jun Yan, Kuangxi Shi, Chengtao Zhao, Limin Yang,* and Guofu Zhong,* J. Org. Chem., 2017, 82, 9779-9785. Weinreb amide directed cross-coupling reaction between electron-deficient alkenes catalyzed by a rhodium catalyst, Feifei Li, Chunbing Yu, Jian Zhang,* and Guofu Zhong,* Org. Biomol. Chem., 2017, 15, 1236-1244. Construction of tetrahydropyranoquinoline derivatives via an asymmetric organocatalytic aza-Michael-IED/HAD cascade reaction, Lu Dai, Yuxuan Hou, Lvye Zhang, Zhangtao Chen, Xiaofei Zeng,* and Guofu Zhong,* Org. Biomol. Chem., 2017, 15, 9630-9637. Amide directed cross-coupling between alkenes and alkynes: a regio- and stereoselective approach to substituted (2Z,4Z)-dienamides, Keke Meng, Jian Zhang,* Feifei Li, Zhenwei Lin, Ke Zhang, and Guofu Zhong,* Org. Lett., 2017, 19, 2498-2501. TiCl4/DMAP mediated Z-selective knovenagel condensation of isatins with nitroacetates and related compounds, Luyi Zhu, Peipei Yan, Lvye Zhang, Zhangtao Chen, Xiaofei Zeng,* and Guofu Zhong,* RSC Adv., 2017, 7, 51352-51358.

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