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主要研究和感兴趣的领域: 主要从事小分子化合物的合成、生物活性筛选及其体内外作用机制的研究。

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Yan Wang,Yan Peng*, Yingqiong Zhou, Yuanhua Zhou, Hui Zhong. The Clinical Value of LRRC3B Gene Expression and Promoter Hypermethylation in Breast Carcinomas. Cell Biochem Biophys, 2014. DOI 10.1007/s12013-014-0018-1 (IF=2.38) Yan Peng, Hui Zhong, Zhen-Feng Chen*, Yan-Cheng Liu, Guo-Hai Zhang, Qi-Pin Qin, and Hong Liang*. A Planar Schiff Base Platinum(II) Complex: Crystal Structure, Cytotoxicity and Interaction with DNA. Chem. Pharm. Bull, 62(3): 221–228, 2014. (IF=1.546) Guohai Zhang, Lejing Cai, Yanfei Wang, Yuanhua Zhou, Yunfeng An, Yancheng Liu, Yan Peng*, Zhenfeng Chen*, Hong Liang*. Novel compound PS-1exhibits selective inhibition in non–small-cell lung cancer cell by blocking the EGFR-driven antiapoptotic pathway. Biochem. Pharmacol., 86(12): 1721-1730, 2013. (IF=4.65) Yan Peng, Min-Min Zhang, Zhen-Feng Chen*, Kun Hu, Yancheng Liu, Xia Chen, Hong Liang. Synthesis, characterization and interaction with biomolecules of platinum(II) complexes with shikimic acid-based ligands. Bioinorg. Chem. Appl., ID 565032, 1-12, 2013. (IF=1.165) Ye Zhang, Yilin Fang, Hong Liang, Hengshan Wang, Kun Hu, Xianxian Liu, Xianghui Yi*, Yan Peng*. Synthesis and antioxidant activities of 2-oxo-quinoline-3-carbaldehyde Schiff-base derivatives. Bioorganic & Medicinal Chemistry Letters, 23, 107-111, 2013. (IF=2.338) Zhen-Feng Chen*, Yan Peng, Yun-Qiong Gu, Yan-Cheng Liu, Mei Liu, Ke-Bin Huang, Kun Hu and Hong Liang*. High antitumor activity of 5,7-dihalo-8-quinolinolato tin(IV) complexes. Eur. J. Med. Chem., 62, 51-58, 2013. (IF=3.499) Zhen-Feng Chen*, Yun-Qiong Gu, Xiao-Yan Song, Yan-Cheng Liu, Yan Peng and Hong Liang*, Synthesis, crystal structure, cytotoxicity and DNA interaction of 5,7-dichloro-8-quinolinolato-lanthani-des. Eur. J. Med. Chem., 59, 194-202, 2013. (IF=3.499) Yan-Cheng Liu, Zhen-Feng Chen*, Xiao-Yan Song, Yan Peng, Qi-Pin Qin and Hong Liang*, Synthesis, crystal structure, cytotoxicity and DNA interaction of 5,7-dibromo-8-quinolinolato-lanthanides. Eur. J. Med. Chem., 59, 168-175, 2013. (IF=3.499) Zhen-Feng Chen*, Yan-Fang Shi, Yan-Cheng Liu, Xue Hong, Bo Geng, Yan Peng, Hong Liang*. TCM active ingredient oxoglaucine metal complexes: crystal structure, cytotoxicity, and interaction with DNA. Inorg. Chem., 51(4): 1998-2009, 2012. (IF=4.593) Zhen-Feng Chen*, Yan-Cheng Liu, Yan Peng, Xue Hong, Hong-Hong Wang, Min-Min Zhang, Hong Liang. Synthesis, characterization, and in vitro antitumor properties of gold(III) compounds with the traditional Chinese medicine (TCM) active ingredient liriodenine. J. Biol. Inorg. Chem. 17, 247-261, 2012. (IF=3.353) Yan-Cheng Liu, Xiao-Yan Song, Zhen-Feng Chen*, Yun-Qiong Gu, Yan Peng, Hong Liang*. Synthesis, crystal structure, DNA interaction and cytotoxicity of a dinuclear nickel(II) complex with 5,7-dichloro-8-hydroxylquinoline. Inorganica Chimica Acta. 382, 52-58, 2012. (IF=1.687) Zhen-Feng Chen*, Ming-Xiong Tan, Yan-Cheng Liu, Yan Peng, Hong-Hong Wang, Hua-Gang Liu*, Hong Liang*, Synthesis, characterization and preliminary cytotoxicity evaluation of five Lanthanide(III)-Plumbagin complexes. J. Inorg. Biochem., 105, 426-434, 2011. (IF=3.197) Zhen-Feng Chen*, Li Mao, Li-Min Liu, Yan-Cheng Liu, Yan Peng, Xue Hong, Hong-Hong Wang, Hua-Gang Liu, Hong Liang*. Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) matrine with Ga(III), Au(III), Sn(IV) ions, and DNA binding studies. J. Inorg. Biochem., 105, 171-180, 2011. (IF=3.197) Zhen-Feng Chen*, Xiao-Yan Song, Yan Peng, Xue Hong, Yan-Cheng Liu, Hong Liang*, High cytotoxicity of dihalo-substituted 8-quinolinolato-lanthanides. Dalton Trans., 40, 1684-1692, 2011. (IF=3.806)

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