刘延成 - 广西师范大学 - 化学与药学学院

研究领域

主要从事无机药物化学与生物无机化学研究。研究方向为：①以高活性蒽腙配体合成系列铂类抗肿瘤配合物及其作用机制研究；②新型金属基动物专用药的研制。

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Yan-Cheng Liu, Zhen-Feng Chen*, Li-Min Liu, et al. Divalent later transition metal complexes of the traditional Chinese medicine (TCM) liriodenine: coordination chemistry, cytotoxicity and DNA binding studies. Dalton Trans., 2009, 48, 10813-10823 Zhen-Feng Chen*, Yan-Cheng Liu, Li-Min Liu, et al. Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) liriodenine with metal ions, and DNA binding studies. Dalton Trans., 2009, 2, 262-272 Zhen-Feng Chen*, Yan-Cheng Liu, Yan Peng, et al. Synthesis, characterization, and in vitro antitumor properties of gold(III) compounds with the traditional Chinese medicine (TCM) active ingredient liriodenine. J. Biol. Inorg. Chem., 2012, 17(2), 247-261 Yan-Cheng Liu, Xiao-Yan Song, Zhen-Feng Chen*, et al. Synthesis, crystal structure, DNA interaction and cytotoxicity of a dinuclear nickel(II) complex with 5,7-dichloro-8-hydroxylquinoline. Inorganica Chimica Acta, 2012, 382, 52-58 Yan-Cheng Liu, Zhen-Feng Chen*, Xiao-Yan Song, et al. Synthesis, crystal structure, cytotoxicity and DNA interaction of 5,7-dibromo-8-quinolinolato-lanthanides. Eur. J. Med. Chem., 2013, 59, 168-175 Yan-Cheng Liu, Jian-Hua Wei, Zhen-Feng Chen*, et al. The antitumor activity of zinc(II) and copper(II) complexes with 5,7-dihalo-substituted-8-quinolinoline. Eur. J. Med. Chem., 2013, 69, 554-563 Zhen-Feng Chen*, Yan-Cheng Liu, Ke-Bin Huang, Hong Liang*. Alkaloid-metal based anticancer agents. Curr. Top. Med. Chem., 2013, 13(17), 2104-2115 Yan-Cheng Liu, Zhen-Feng Chen*, Yan-Fang Shi, et al. Oxoglaucine-lanthanide complexes: Synthesis, crystal structure and cytotoxicity. Anticancer Research, 2014, 34(1), 531-536 Yu-Lan Li, Qi-Pin Qin, Yan-Cheng Liu*, et al. A platinum(II) complex of liriodenine from traditional Chinese medicine (TCM): Cell cycle arrest, cell apoptosis induction and telomerase inhibition activity via G-quadruplex DNA stabilization, J. Inorg. Biochem., 2014, 137, 12-21 Xu-Jian Luo, Qi-Pin Qin, Yu-Lan Li, Yan-Cheng Liu*, et al. Three platinum(II) complexes of 2-(methoxy-phenyl)-imidazo-[4,5-f]-[1,10] phenanthroline: Cell apoptosis induction by sub-G1 phase cell cycle arrest and G-quadruplex binding properties, Inorg. Chem. Commun., 2014, 46, 176-179