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Discovery of N-(2-chloro-5-(3-(pyridin-4-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yl)-4-fluorobenzenesulfonamide (FD274) as a highly potent PI3K/mTOR dual inhibitor for the treatment of acute myeloid leukemia , Chengbin Yang, Yi Chen, Tianze Wu, Yunjian Gao, Xiaofeng Liu, Yongtai Yang, Yun Ling, Yu Jia, Mingli Deng*, Jianxin Wang, Yaming Zhou,* European Journal of Medicinal Chemistry, 2023, 258, 115543
Nanosheets of two-dimensional photoluminescent Lanthanide phosphonocarboxylate frameworks decorated with free carboxylic groups for latent fingerprint imaging , Dan Luo, Hongjie He, Huiru Jing, Yun Ling, Yu Jia, Yongtai Yang, Xiaofeng Liu, Zhenxia Chen* and Mingli Deng* Dalton Transcations, 2023, 52, 9208-9214
Discovery of a high potent PIM kinase inhibitor for acute myeloid leukemia based on N-pyridinyl amide scaffold by optimizing the fragments toward to Lys67 and Asp128/Glu171 , Ruiqing Xiang, Mingzhu Lu, Tianze Wu, Chengbin Yang, Yu Jia, Xiaofeng Liu, Mingli Deng,**, Yu Ge, Jun Xu, Tong Cai, Yun Ling, Yaming Zhou,* European Journal of Medicinal Chemistry, 2023, 223, 257, 115514
Design, synthesis and in vitro biological evaluation of 2-aminopyridine derivatives as novel PI3Kδ inhibitors for hematological cancer, Chengbin Yang, Yimin Gong, Yunjian Gao, Mingli Deng, Xiaofeng Liu, Yongtai Yang, Yun Ling, Yu Jia*, Yaming Zhou*; Bioorg. Med. Chem. Lett., 2023, 82, 129152
A Pyridinesulfonamide Derivative FD268 Suppresses Cell Proliferation and Induces Apoptosis via Inhibiting PI3K Pathway in Acute Myeloid Leukemia, Yi Chen, Tianze Wu, Chengbin Yang, Mingzhu Lu, Zhenxia Chen, Mingli Deng, Yu Jia, Yongtai Yang, Xiaofeng Liu, Hongyan Wang, Yun Ling,, Lei Lu,* Yaming Zhou*; PLoS ONE, 2022, 17(11):e0277893
Unprecedented Ferromagnetic Exchange Coupling of a Square-Planar Cu4O unit in a scu-Type Porous Metal–Organic Framework and Its Reticular Chemistry, Tianze Qiu, Yongchen Wang, Yihan Li, Lin Zhu*, Zhenxia Chen, Yu Jia, Pu Zhao, Wei Shi, Yaming Zhou, and Yun Ling*; Cryst. Growth Des., 2022, 22, 7, 4005–4011
Hollow carbon nanospheres embedded with stoichiometric γ-Fe2O3 and GdPO4: tuning the nanospheres for in vitro and in vivo size effect evaluation, Hui Zhang, Jianping Zhang, Yi Chen, Tianze Wu, Mingzhu Lu, Zhenxia Chen, Yu Jia, Yongtai Yang, Yun Ling* and Yaming Zhou*; Nanoscale Advances, 2022, 4, 1414
Development of Anti-Breast Cancer PI3K Inhibitors Based on 7-Azaindole Derivatives through Scaffold Hopping: Design, Synthesis and in Vitro Biological Evaluation, Chengbin Yang, Mingzhu Lu, Yi Chen, Ruiqing Xiang, Tianze Qiu, Yu Jia, Yongtai Yang, Xiaofeng Liu, Mingli Deng, Yun Ling, Yaming Zhou*; Bioorganic Chemistry, 2021, 117, 105405
Post-synthetic anchoring Fe(III) into a fcu-type Zr-MOF for the catalyzed hydrolysis of 5-hydroxylmethoxyfurfural, Mengmeng Zhang, Jiaying Lou, Rui Xu, Peng Li, Yunfei Sha, Hui Zhang, Yu Jia, Zhenxia Chen, Da Wu*, Yun Ling*, YamingZhou; Microporous Mesoporous Materials, 2021, 328, 111449
Reticular Chemistry Approach to Explore the Catalytic CO2-epoxide Cycloaddition Reaction over Tetrahedral Coordination Lewis Acidic Sites in a Rutile-type Zinc-phosphonocarboxylate Framework, Lingtao Kong, Zhouxun Li, Han Hu, Jiaxing Zhu, Zhenxia Chen*, Mingli Deng*, Yun Ling, Peng Li, Yu Jia, Yaming Zhou; Chemical Engineering Journal, 2022, 427,131759
Discovery of cinnoline derivatives as potent PI3K inhibitors with antiproliferative activity, Chengze Tian, Chengbin Yang, Tianze Wu, Mingzhu Lu, Yi Chen, Yongtai Yang, Xiaofeng Liu, Yun Ling, Mingli Deng, Yu Jia*, Yaming Zhou* Bioorganic & Medicinal Chemistry Letters, 2021, 48, 128271
Bioisosteric replacements of the indole moiety for the development of a potent and selective PI3Kδ inhibitor: Design, synthesis and biological evaluation, Chengbin Yang， Chenyue Xu， Zhipeng Li， Yi Chen， Tianze Wu， Hui Hong， Mingzhu Lu， Yu Jia, Yongtai Yang, Xiaofeng Liu, Mingli Deng, Zhenxia Chen, Qingquan Li*, Yun Ling*, Yaming Zhou* European Journal of Medicinal Chemistry, 2021, 223, 1136613
Hollow carbon nanospheres dotted with Gd–Fe nanoparticles for magnetic resonance and photoacoustic imaging, Hui Zhang, Tianze Wu, Yi Chen, Qianqian Zhang, Zhenxia Chen, Yun Ling,* Yu Jia, Yongtai Yang, Xiaofeng Liu and Yaming Zhou* Nanaoscale, 2021, 13, 10943-10952
Multimetal lanthanide phosphonocarboxylate frameworks: structure, colour tuning and near-infrared emission, Huiru Jing, Wenyan Dan, Jiaxing Zhu, Yun Ling, Yu Jia, Yongtai Yang, Xiaofeng Liu, Zhenxia Chen* and Yaming Zhou* Dalton Transcations, 2021, 50, 7380 - 7387
TEA-assistant synthesis of MOF-74 nanorods for drug delivery and in-vitro magnetic resonance imaging, Jiaqi Hu, Yi Chen, Hui Zhang, Zhenxia Chen*, Yun Ling, Yongtai Yang, Xiaofeng Liu, Yu Jia, Yaming ZhouMicroporous Mesoporous Materials, 2021, 315, 110900
Generation and Reactions of Heteroaromatic Lithium Compounds by Using In-Line Mixer in a Continuous Flow Microreactor System at Mild Conditions Org. Process Res. Dev.,2013, 17, 133−137.
Efficient Claisen rearrangement of allyl para-substituted phenyl ethers using microreactors Green Chem.,2009, 11, 1108-1111.
Efficient Synthesis of Imidazoles from Aldehydes and 1,2-Diketones under Superheating Conditions by Using a Continuous Flow Microreactor System under Pressure Org. Process Res. Dev.,2010, 14(4), 902-904.
Clean and Efficient Benzylic C-H Oxidation Using a Microflow System Synthetic Communications., 2011, 41, 3215–3222.
N-Heterocyclization of Primary Amines with Dihalides Using Microreactors Synthetic Communications, 2012, 42, 2512–2525.
One-dimensional (1D) helical and 2D homochiral metal–organic frameworks built from a new chiral octahydrobinaphthalene-derived dicarboxylic acid Inorg. Chem. Commun., 2008, 11(9), 948-950.
Supramolecular Isomerism of Metal-Organic Frameworks Derivedfrom a Bicarboxylate Linker with Two Distinct Binding Motifs Cryst. Growth Des., 2009, 9(3), 1505-1510.
Synthesis and crystal structures of four pH-dependent Pb(II) and Cd(II)phosphonates based on a novel ligand, 3-phosphono-benzoic acid Inorg. Chim. Acta, 2009, 362, 2101-2107.
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