魏邦国 - 复旦大学

个人简介

教育经历 1994.09 – 1998.07 西北师范大学化学系 1998.09 – 2001.07 西北师范大学化学化工学院有机化学专业硕士研究生 2001.09 – 2004.09 厦门大学化学化工学院有机化学专业博士研究生工作经历 2004.10 – 2006.08 中国科学院上海有机化学研究所，博士后 2006.08 – 2016.12 复旦大学化学系/药学院，副研究员 2016.12 –至今复旦大学药学院，研究员获奖及荣誉 2012.05 第二十四届上海市优秀发明选拔赛优秀发明金奖 (第二完成人） 2011.12 上海市药学会科技奖二等奖（第二完成人） 2011.07 中国药学会科技奖二等奖（第七完成人） 2010.12 上海市药学会科技奖二等奖（第七完成人） 2005.04 甘肃省科技进步奖二等奖 (第七完成人） 2004.07 甘肃省高校科技进步奖一等奖 (第七完成人） 2002.10 甘肃省高校科技进步奖二等奖 (第五完成人）

研究领域

活性导向天然产物及其骨架高效合成方法学研究资源导向复杂海洋天然产物及氮杂环生物碱的多样性合成研究复杂药物分子的高效产业化研究

近期论文

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Chang-Hong Liu, Jia-Ming Guo, Xin Li, Jian-Ting Sun, Bang-Guo Wei* and Chang-Mei Si* SmI2-mediated intermolecular addition–elimination of piperidine and pyrrolidine N-α-radicals with arylacetylene sulfones Chem. Commun.2022, 58,10841-10844. ia-Ming Guo, Zhuo-Ya Mao, Chang-Hong Liu, Shang-Ye Yang, and Bang-Guo Wei* Palladium-Catalyzed Sequential Heck Reactions of Olefin-Tethered Aryl Iodides with Alkenes J. Org. Chem.2022, 87, 11838-11845. Xiao-Di Nie, Zhuo-Ya Mao, Jia-Ming Guo, Chang-Mei Si,* Bang-Guo Wei* and Guo-Qiang LinAgNTf2?Catalyzed Regioselective C-H Alkenylation of N,N-Dialkylanilines with Ynamides J. Org. Chem.2022, 87, 2380-2392. Chao-Yu Hu, Sheng-Jie Wu, Fei He, De-Qin Cai, Zhuo-Jia Xu, Wen-Jing Ma, Ya-Ting Liu, Bang-Guo Wei,* Tie-Hai Li,* and Kan Ding*Convergent Synthesis and Anti-Pancreatic Cancer Cell Growth Activity of a Highly Branched Heptadecasaccharide from Carthamus tinctoriusAngew. Chem. Int. Ed.2022,doi.org/10.1002/anie.202202554. Zhuo-Ya Mao, Xiao-Di Nie, Yi-Man Feng, Chang-Mei Si, Bang-Guo Wei* and Guo-Qiang Lin Cu(OTf)2 catalyzed Ugi-type reaction of N,O-acetals with isocyanides for the synthesis of pyrrolidinyl and piperidinyl 2-carboxamides Chem. Commun. 2021, 57, 9248-9251. Zhuo-Ya Mao, Jian-Liang Ye, Xiao-Di Nie, Chang-Mei Si, Bang-Guo Wei* and Guo-Qiang Lin Synthesis of Functionalized Bicyclo[2.2.2]octan-2-ones Skeleton via Tandem Process of Amino Acid Involved Formal [4+2] and Decarboxylative?Mannich Sequence J. Org. Chem.2021, 86, 3276-3286. Xiao-Di Nie, Xiao-Li Han, Jian-Ting Sun, Chang-Mei Si*, Bang-Guo Wei* and Guo-Qiang Lin Nickel-Catalyzed Regioselective Hydroamination of Ynamides with Secondary Amines J. Org. Chem.2021, 86, 3433-3443. Zhao-Dan Chen, Wen-Ke Xu, Jia-Ming Guo, Ling Chen, Bang-Guo Wei*, Chang-Mei Si* and Guo-Qiang Lin A One-Pot Approach to 2?Substituted-2-(Dimethoxyphosphoryl)-Pyrrolidines from Substituted tert-Butyl 4?Oxobutylcarbamates and Trimethyl Phosphite J. Org. Chem. 2021, 86, 11442-11455. Xiao-Li Han, Xiao-Di Nie, Yi-Man Feng, Bang-Guo Wei*, Chang-Mei Si* and Guo-Qiang LinIntermolecular [4+2] process of N -acyliminium ions with simple olefins for construction of functional substituted-1,3-oxazinan-2-ones Chin. Chem. Lett.2021, 32, 3526-3530. Chen Wang, Zhuo-Ya Mao, Yi-Wen Liu, Qiao-E Wang, Chang-Mei Si*, Bang-Guo Wei* and Guo-Qiang Lin Stereoselective Intermolecular [4+2] Process of N,O-acetals with Terminal Alkynes for Construction of Functional cis-Pyrido and Pyrrolo[1,2-c][1,3]oxazin-1-ones Adv. Synth. Catal. 2020, 362, 822-831. Xiao-Di Nie, Zhuo-Ya Mao, Wen Zhou, Chang-Mei Si*, Bang-Guo Wei* and Guo-Qiang Lin A diastereoselective approach to amino alcohols and application for divergent synthesis of dolastatin 10 Org. Chem. Front.2020, 7, 76-103. Pan Han, Zhuo-Ya Mao, Ming Li, Chang-Mei Si*, Bang-Guo Wei* and Guo-Qiang Lin Synthesis of Amide Enol Carbamates and Carbonates through Cu(OTf)2?Catalyzed Reactions of Ynamides with t?Butyl Carbamates/Carbonates J. Org. Chem.2020, 85, 4740-4752. Xiao-Li Han, Xiao-Di Nie, Zhao-Dan Chen, Chang-Mei Si*, Bang-Guo Wei* and Guo-Qiang Lin Synthesis of a 3,4-Dihydro-1,3-oxazin-2-ones Skeleton via an Intermolecular [4+2] Process of N?Acyliminium Ions with Ynamides/Terminal Alkynes J. Org. Chem. 2020, 85, 13567-13578. Yan-Xue Zhang, Ling-Yan Chen*, Jian-Ting Sun, Chang-Mei Si and Bang-Guo Wei* Gold-Catalyzed Addition?N?Boc Cleavage-Cyclization of N,O?Acetal with Ynamides for Construction of 6?(tert-Butyldimethylsilyl)oxytetrahydropyrrolo[1,2?c][1,3]oxazin-1-ones J. Org. Chem. 2020, 85, 12603-12613. Zhuo-Ya Mao, Yi-Wen Liu, Rui-Jun Ma, Chang-Mei Si, Bang-Guo Wei* and Guo-Qiang Lin Divergent Synthesis of N-Heterocyclic 1,6-Enynes through Zinccatalyzed Decarboxylative A3 ReactionChem. Commun.2019, 55, 14170-14173. Pan Han, Zhuo-Ya Mao, Chang-Mei Si, Zhu Zhou, Bang-Guo Wei* and Guo-Qiang Lin Stereoselective Synthesis of Pyrido- and Pyrrolo[1,2?c][1,3]oxazin-1-ones via a Nucleophilic Addition-Cyclization Process of N,O?Acetal with Ynamides J. Org. Chem. 2019, 84, 914-923. Yi-Wen Liu, Zhuo-Ya Mao, Xiao-Di Nie, Chang-Mei Si, Bang-Guo Wei* and Guo-Qiang Lin Approach to Tertiary-Type β?Hydroxyl Carboxamides Through Sc(OTf)3?Catalyzed Addition of Ynamides and Ketones J. Org. Chem.2019, 84, 16254-16261. Xue-Mei Wang, Yi-Wen Liu, Rui-Jun Ma, Chang-Mei Si* and Bang-Guo Wei* Synthesis of 1,4- and 1,5-Amino Alcohols via Nucleophilic Addition of Semicyclic N,O?Acetal with Organozinc Reagents J. Org. Chem. 2019, 84, 11261-11267. Zhuo-Ya Mao, Yi-Wen Liu, Pan Han, Han-Qing Dong, Chang-Mei Si,* Bang-Guo Wei* and Guo-Qiang Lin Regio- and Stereoselective Cascades via Aldol Condensation and 1,3-Dipolar Cycloaddition for Construction of Functional Pyrrolizidine Derivatives Org. Lett.2018,20, 1090-1093. Wen Zhou, Yan-Xue Zhang, Xiao-Di Nie, Chang-Mei Si,* Xun Sun, and Bang-Guo Wei* Approach to Chiral 1?Substituted Isoquinolone and 3?Substituted Isoindolin-1-one by Addition?Cyclization Process J. Org. Chem.2018,83, 9879-9889. Pan Han, Zhu Zhou, Chang-Mei Si,* Xian-Yi Sha, Zheng-Yi Gu, Bang-Guo Wei* and Guo-Qiang Lin Asymmetric Synthesis of Rupestonic Acid and Pechueloic Acid Org. Lett. 2017, 19, 6732-6735. Zhuo-Ya Mao, Chang-Mei Si, Yi-Wen Liu, Han-Qing Dong, Bang-Guo Wei* and Guo-Qiang LinDivergent Synthesis of Revised Apratoxin E, 30-epi-Apratoxin E, and 30S/30R?Oxoapratoxin EJ. Org. Chem. 2017,82, 10830-10845. Lu-Ping Shao, Chang-Mei Si, Zhuo-Ya Mao, Wen Zhou, Tadeusz F. Molinski,* Bang-Guo Wei* and Guo-Qiang Lin Synthesis and structure revision of symplocin A Org. Chem. Front.2017, 4, 995-1004. Chang-Mei Si, Zhuo-Ya Mao, Yi-Wen Liu, Zhen-Ting Du, Bang-Guo Wei* and Guo-Qiang Lin Stereoselective Formation of Chiral trans-4-Hydroxy-5-Substituted 2-Pyrrolidinones: Syntheses of Streptopyrrolidine and3-epi-Epohelmin A Org. Chem. Front.2015, 2, 1485-1499. Chang-Mei Si, Zhuo-Ya Mao, Han-Qing Dong, Zhen-Ting Du, Bang-Guo Wei* and Guo-Qiang Lin Divergent Method to trans-5-Hydroxy-6-alkynyl/alkenyl-2-piperidinones: Syntheses of (-)-Epiquinamide and (+)-SwainsonineJ. Org. Chem.2015, 80, 5824-5833. Chang-Mei Si, Wei Huang, Zhen-Ting Du, Bang-Guo Wei* and Guo-Qiang Lin Diastereoconvergent Synthesis of trans-5-Hydroxy-6-Substituted-2-Piperidinones by Addition?Cyclization?Deprotection Process Org. Lett. 2014, 16, 4328-4331. Wei Huang,Jian-Liang Ye,Wei Zheng,Han-Qing Dong and Bang-Guo Wei* Radical Migration?Addition of N-tert-Butanesulfinyl Imines with Organozinc Reagents J. Org. Chem. 2013, 78, 11229-11237. Wei Huang, Rong-Guo Ren, Han-Qing Dong, Bang-Guo Wei* and Guo-Qiang Lin Diverse Synthesis of Marine Cyclic Depsipeptide Lagunamide A and Its Analogues J. Org. Chem. 2013, 78, 10747-10762.