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Sun Zhenyu, Fu Bin, Wang Guoli, Zhang Lei, Xu Ruofan, Zhang Ying*, Lu Haojie* High-throughput site-specific N-glycoproteomics reveals glyco-signatures for liver disease diagnosis. Nat. Sci. Rev., 2022, DOI: 10.1093/nsr/nwac059
Linlin Wu, Fei Weiwei, Liu Zhiyong, Zhang Lei, Fang Caiyun*, and Lu Haojie* Specific and reversible enrichment of early-stage glycated proteome based on thiazolidine chemistry and palladium-mediated cleavage. Anal Chem, 2022, 94, 13, 5213-5220.
Cheng Mengxia, Shu Hong, Yang Maohua, Yan Guoquan, Zhang Lei, Wang Liang, Wang Wenning, and Lu Haojie* Fast discrimination of sialylated N-Glycan linkage isomers with one-step derivatization by microfluidic capillary electrophoresis-mass spectrometry. Anal Chem, 2022, 94, 11, 4666–4676.
Wang Zhongjie, Yuan Wenjuan, Zhang Lei, Zhang Ying, Lu Haojie* NAPT, an unbiased approach for sequential analysis of protein N- and C- terminome. Chem Commun, 2022, 58, 9397-9400
Wu Linlin, Fang Caiyun, Zhang Lei, Yuan Wenjuan, Yu Xiaofang*, Lu Haojie* Integrated strategy for discovery and validation of glycated candidate biomarkers for hemodialysis patients with cardiovascular complications. Anal Chem, 2021, 93,4398−4407
Cheng Mengxia, Shu Hong, Peng Ye, Feng Xiaoxiao, Yan Guoquan, Zhang Lei, Yao Jun, Bao Huimin, Lu Haojie* Specific analysis of α-2,3-sialylated N-Glycan linkage isomers by microchip capillary electrophoresis-mass Spectrometry. Anal Chem, 2021, 93, 5537–5546
Shao Yuyin, Bao Huimin*, Ma Lixiang, Yuan Wenjuan, Zhang Lei, Yao Jun, Meng Peiyi, Peng Ye, Zhang Siwen, Cao Ting, Lu Haojie* Enhancing comprehensive analysis of newly synthesized proteins based on cleavable bioorthogonal tagging. Anal. Chem., 2021, 93, 27, 9408-9417
Wang Zhongjie, Zhang Lei, Yuan Wenjuan, Zhang Ying *, Lu Haojie* SAPT, a fast and efficient approach for simultaneous profiling of protein N- and C-terminome. Anal Chem, 2021, 93, 30, 10553–10560.
Feng Xiaoxiao, Shu Hong, Zhang Shu, Peng Ye, Zhang Lei, Cao Xinyi, Wei Liming* and Lu Haojie* Relative Quantification of N-Glycopeptide Sialic Acid Linkage Isomers by Ion Mobility Mass Spectrometry. Anal Chem, 2021,93, 47, 15617-15625
Du Xiaoxian, Lu Jingtian, Yang Lijun, Bao Huimin, Zhang Lei, Yan Guoquan, Fang Caiyun*, Lu Haojie* Rapid and Easy Enrichment Strategy for Naturally Acetylated N-Termini Based on LysN Digestion and Amine-reactive Resin Capture. Analytical Chemistry, 2020, 92, 12, 8315–8322
Di Yi, Zhang Lei, Zhang Ying, Zhao Huanhuan, Yan Guoquan, Yao Jun, Zhang Shu and Lu Haojie*, MdCDPM: A Mass Defect-Based Chemical-Directed Proteomics Method for Targeted Analysis of Intact Sialylglycopeptides. Analytical Chemistry, 2019, 91, 9986-9992.
Du Xiaoxian, Fang Caiyun, Yang Lijun, Bao Huimin, Zhang Lei, Yan Guoquan and Lu Haojie*, In-Depth Analysis of C Terminomes Based on LysC Digestion and Site-Selective Dimethylation. Analytical Chemistry, 2019, 91, 6498-6506.
Yang Lijun, Du Xiaoxian, Peng Ye, Cai Yan, Wei Lei, Zhang Ying* and Lu Haojie*, Integrated Pipeline of Isotopic Labeling and Selective Enriching for Quantitative Analysis of N-Glycome by Mass Spectrometry. Analytical Chemistry, 2019, 91, 1486-1493.
Zhang Siwen, Fang Caiyun, Yuan Wenjuan, Zhang Ying, Yan Guoquan, Zhang Lei, Di Yi, Cai Yan and Lu Haojie*, Selective Identification and Site-Specific Quantification of 4-Hydroxy-2-nonenal-Modified Proteins. Analytical Chemistry, 2019, 91, 5235-5243.
Yang Lijun, Sun Zhenyu, Lei Zhang, Yan Cai, Ye Peng, Ting Cao, Ying Zhang* and Lu Haojie*. Chemical labeling for fine mapping of IgG Nglycosylation by ETD-MS. Chem. Sci., 2019, 10, 9302-9307
Yang Lijun, Peng Ye, Jiao Jing, Tao Tao, Yao Jun, Zhang Ying*, LuHaojie*.Metallic element chelated tag labeling (MeCTL) for quantitation of N-Glycans in MALDI-MS. Analytical Chemistry. 2017, 89, 7470–7476.
Tong Qinghe, Yan Tianyang, Tao Tao, Zhang Lei, Xie Liqi* and LuHaojie*. Reductive amination combining dimethylation for quantitative analysis of early-stage glycated proteins. Analytical Chemistry, 2018, 90, 3752−3758.
Wei Lei, Cai Yan, Yang Lijun, Zhang Ying * andLu Haojie*. Duplex stable isotope labeling (DuSIL) for simultaneous quantitation and distinction of sialylated and neutral N Glycans by MALDI-MS. Analytical Chemistry, 2018, 90,10442−10449.
Zhang Ying, Peng Ye, Yang Lijun, LuHaojie*, Advances in sample preparation strategies for MS-based qualitative and quantitative N-glycomics. Trends in Analytical Chemistry, 2018, 99:34-46.
Zhang Xiaoqin, Zhang Yuting, Fang Caiyun*, Zhang Lei, Yang Pengyuan, Wang Changchun and Lu Haojie*. Ultradeep palmitoylomics enabled by dithiodipyridine-functionalized magnetic nanoparticles. Analytical Chemistry,2018, 90, 6161−6168.
Zhang Xiaoqin, Zhang Lei, Ji Guanghui, Lei Qunying, Fang Caiyun * and LuHaojie*. Site-specific quantification of protein palmitoylation by cysteine-stable isotope metabolic labeling. Analytical Chemistry, 2018, 90,10543−10550.
Di Yi, Zhang Ying, Zhang Lei, Tao Tao, Lu Haojie* MdFDIA: A mass defect based four-plex data-independent acquisition strategy for proteome quantification. Analytical Chemistry. 2017, 89, 10248–10255.
Cao Ting, Zhang Lei, Zhang Ying, Yan Guoquan, Fang Caiyun, Bao Huimin, Lu Haojie*. Site-specific quantification of protein ubiquitination on MS2 fragment ion level via isobaric peptide labeling. Analytical Chemistry. 2017, 89, 11468-11475.
Yuan Wenjuan, Zhang Ying, Xiong Yun, Tao Tao, Wang Yi, Yao Jun, Zhang Lei, Yan Guoquan, Bao Huimin, Lu Haojie*. Highly selective and large scale mass spectrometric analysis of 4-Hydroxynonenal modification via fluorous derivatization and fluorous solid-phase extraction. Analytical Chemistry. 2017, 89, 3093-3100.
Lu Haojie, Zhang Ying, Yang Pengyuan* Advancements in mass-spectrometry based glycoproteomics and glycomics. National Science Reviews, 2016, 3, 345-364.
Tong Qinghe, Tao Tao, Xie Liqi*, Lu Haojie*. ELISA-PLA: A novel hybrid platform for the rapid, highly sensitive and specific quantification of proteins and post-translational modifications. Biosensors & Bioelectronics, 2016, 80, 385-391.
Li Lulu, Jiao Jing, Cai Yan, Zhang Ying*, Lu Haojie*. Fluorinated Carbon Tag Derivatization Combined with Fluorous Solid-Phase Extraction: A New Method for the Highly Sensitive and Selective Mass Spectrometric Analysis of Glycans. Analytical Chemistry. 2015, 87, 5125-5131.
Zhang Ying, Zhang Cheng, Jiang Hucong, Yang Pengyuan, Lu Haojie*. Fishing the PTM proteome with chemical approaches using functional solid phases. Chemical Society Reviews. 2015, 44, 8260-8287.
Li Wei, Liu Minbo, Feng Shanshan, Li Xiaomin, Wang Jinxiu, Shen Dengke, Li Yuhui, Sun Zhenkun, Elzatahry Ahmed A., Lu Haojie*, Zhao Dongyuan* Template-free synthesis of uniform magnetic mesoporous TiO2 nanospindles for highly selective enrichment of phosphopeptides. Materials Horizons. 2014, 1, 439-445.
Liu Liting, Yu Meng, Zhang Ying, Wang Changchun*, Lu Haojie* Hydrazide Functionalized Core-Shell Magnetic Nanocomposites for Highly Specific Enrichment of N-Glycopeptides.Acs Applied Materials & Interfaces. 2014, 6, 7823-7832.
Wang Yali, Liu Minbo, Xie Liqi, Fang Caiyun, Xiong Huanming*, Lu Haojie*. Highly Efficient Enrichment Method for Glycopeptide Analyses: Using Specific and Nonspecific Nanoparticles Synergistically. Analytical Chemistry. 2014, 86, 2057-2064.
Zhang Ying, Ma Wanfu, Zhang Cheng, Wang Changchun*,Lu Haojie*.Titania Composite Microspheres Endowed with a Size-Exclusive Effect toward the Highly Specific Revelation of Phosphopeptidome. Acs Applied Materials & Interfaces. 2014, 6, 6290-6299.
Zhang Ying, Yu Meng, Zhang Cheng, Ma Wanfu, Zhang Yuting, Wang Changchun*, Lu Haojie*. Highly Selective and Ultra Fast Solid-Phase Extraction of N-Glycoproteome by Oxime Click Chemistry Using Aminooxy-Functionalized Magnetic Nanoparticles. Analytical Chemistry. 2014, 86, 7920-7924.
Zhang Ying, Kuang Min, Zhang Lijuan, Yang Pengyuan, Lu Haojie*. An Accessible Protocol for Solid-Phase Extraction of N-Linked Glycopeptides through Reductive Amination by Amine-Functionalized Magnetic Nanoparticles. Analytical Chemistry. 2013, 85, 5535-5541.
Liu Minbo, Zhang Lijuan, Zhang Lei, Yao Jun, Yang Pengyuan,Lu Haojie*. Approach for Identification and Quantification of C-Terminal Peptides: Incorporation of Isotopic Arginine Labeling Based on Oxazolone Chemistry. Analytical Chemistry. 2013, 85 (22), 10745-10753.
Ma Wanfu, Zhang Ying, Li Lulu, You Lijun, Zhang Peng, Zhang Yuting, Li Jumei, Yu Meng, Guo Jia, Lu Haojie*, Wang Changchun*. Tailor-Made Magnetic Fe3O4@mTiO(2) Microspheres with a Tunable Mesoporous Anatase Shell for Highly Selective and Effective Enrichment of Phosphopeptides. ACS Nano. 2012, 6, 3179-3188.
Nie Aiying, Zhang Lei, Yan Guoquan, Yao Jun, Zhang Yang, Lu Haojie*, Yang Pengyuan, He Fuchu. In Vivo Termini Amino Acid Labeling for Quantitative Proteomics. Analytical Chemistry. 2011, 83, 6026-6033.
Xu Yawei, Wu Zhangxiong, Zhang Lijuan,Lu Haojie*, Yang Pengyuan. Webley Paul A., Zhao Dongyuan*, Highly Specific Enrichment of Glycopeptides Using Boronic Acid-Functionalized Mesoporous Silica. Analytical Chemistry. 2009, 81, 503-508.
Xiong Huanming, Guan Xiaoyan, Jin Linghua, Shen Wenwen, Lu Haojie*, Xia Yongyao*. Surfactant-free synthesis of SnO2@PMMA and TiO2@PMMA core-shell nanobeads designed for peptide/protein enrichment and MALDI-TOF MS analysis. Angewandte Chemie-International Edition. 2008, 47, 4204-4207.
CaCO3-poly (methyl methacrylate) nanoparticles for fast enrichment of low-abundance peptides followed by CaCO3-core removal for MALDI-TOF MS analysis. Jia Weitao, Chen Xuehua, Lu Haojie*, Yang Pengyuan*. Angewandte Chemie-International Edition. 2006, 45, 3345-3349.
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