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1.Hu M(#), Zhang Z(#), Liu B(#), Zhang S, Chai R, Chen X, Kong T, Zhang F, Zhang J, Liu S(*), Liu N(*). Deubiquitinase inhibitor auranofin attenuated cardiac hypertrophy by blocking NF-κB activation, Cellular Physiology and Biochemistry. 2018;45(6): 2421-2430. 2.Hu M, Guo G, Huang Q, Cheng C, Xu R, Li A, Liu N(*), Liu S(*). The Harsh Microenvironment in Infarcted Heart Accelerates Transplanted Bone Marrow Mesenchymal Stem Cells Injury: The Role of Injured Cardiomyocytes-derived Exosomes, Cell Death & Disease, 2018; 9:357. 3.Liao Y(#), Xia X(#), Liu N(#), Cai J, Guo Z, Li Y, Jiang L, Dou Q, Tang D, Huang H(*), Liu J(*). Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination. Oncogene. 2018; Epub ahead of print. 4.Liu N (#), Kong T (#), Chen X (#), Hu H, Gu H, Liu S, Chen X, Yang Q, Li A, Xiong X(*), Zhang Z(*). Ubiquitin-specific protease 14 regulates LPS-induced inflammation by increasing ERK1/2 phosphorylation and NF-kappaB activation. Molecular & Cellular Biochemistry. 2017;431:87-96. 5.Huang H(#), Guo M(#), Liu N(#), Zhao C(#), Chen H, Wang X, Liao S, Zhou P, Liao Y, Chen X, Lan X, Chen J, Xu D, Li X, Shi X, Yu L, Nie Y, Wang X, Zhang C(*), Liu J(*). Bilirubin neurotoxicity is associated with proteasome inhibition. Cell Death & Disease. 2017;8(6):e2877. 6.Liu N (#), Chai R (#), Liu B (#), Zhang Z, Zhang S, Zhang J, Liao Y, Cai J, Xia X, Li A, Liu J, Huang H(*), Liu S(*). Ubiquitin-specific protease 14 regulates cardiac hypertrophy progression by increasing GSK-3β phosphorylation. Biochemical and Biophysical Research Communications. 2016;478:1236-41. 7.Liu B (#), Liu N (#), Liu W (#), Zhang S, Zhang J, Li A, Liu S(*). Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces cardiac fibroblast proliferation by suppressing GATA Binding Protein 4. Biochemical and Biophysical Research Communications. 2016;475:329-34. 8.Liu N, Huang H, Dou QP, Liu J(*). Inhibition of 19S proteasome-associated deubiquitinases by metal-containing compounds. Oncoscience. 2015;2:457-66. 9.Huang H(#), Hua X(#), Liu N(#), Li X, Liu S, Chen X, Zhao C, Lan X, Yang C, Dou QP, Liu J(*). Anacardic acid induces cell apoptosis associated with induction of ATF4-dependent endoplasmic reticulum stress. Toxicology Letters. 2014;228:170-8. 10.Liu N(#), Li X(#), Huang H(#), Zhao C(#), Liao S(#), Yang C(#), Liu S(#), Song W, Lu X, Lan X, Chen X, Yi S, Xu L, Jiang L, Zhao C, Dong X, Zhou P, Li S, Wang S, Shi X, Dou PQ, Wang X, Liu J(*). Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth. Oncotarget. 2014;5:5453-71. 11.Liu N(#), Liu C(#), Li X(#), Liao S(#), Song W(#), Yang C(#), Zhao C(#), Huang H(#), Guan L, Zhang P, Liu S, Hua X, Chen X, Zhou P, Lan X, Yi S, Wang S, Wang X, Dou QP, Liu J(*). A novel proteasome inhibitor suppresses tumor growth via targeting both 19S proteasome deubiquitinases and 20S proteolytic peptidases. Scientific Reports. 2014;4:5240. 12.Liu N(#), Huang H(#), Liu S, Li X, Yang C, Dou Q, Liu J(*). Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation. Toxicology in Vitro. 2014;28:419-25. 13.Liu N(#), Huang H(#), Xu L, Hua X, Li X, Liu S, Yang C, Zhao C, Zhao C, Li S, Dou QP, Liu J(*). The combination of proteasome inhibitors bortezomib and gambogic acid triggers synergistic cytotoxicity in vitro but not in vivo. Toxicology Letters. 2014;224:333-40. 14.Li X(#), Liu S(#), Huang H(#), Liu N(#), Zhao C(#), Liao S(#), Yang C, Liu Y, Zhao C, Li S, Lu X, Liu C, Guan L, Zhao K, Shi X, Song W, Zhou P, Dong X, Guo H, Wen G, Zhang C, Jiang L, Ma N, Li B, Wang S, Tan H, Wang X, Dou QP(*), Liu J(*). Gambogic acid is a tissue-specific proteasome inhibitor in vitro and in vivo. Cell Reports. 2013;3:211-22. 15.Huang H(#), Liu N(#), Guo H(#), Liao S, Li X, Yang C, Liu S, Song W, Liu C, Guan L, Li B, Xu L, Zhang C, Wang X, Dou QP, Liu J(*). L-carnitine is an endogenous HDAC inhibitor selectively inhibiting cancer cell growth in vivo and in vitro. PloS One. 2012;7:e49062. 16.Huang H(#), Liu N(#), Yang C(#), Liao S, Guo H, Zhao K, Li X, Liu S, Guan L, Liu C, Xu L, Zhang C, Song W, Li B, Tang P, Dou QP(*), Liu J(*). HDAC inhibitor L-carnitine and proteasome inhibitor bortezomib synergistically exert anti-tumor activity in vitro and in vivo. PloS One. 2012;7:e52576. 17.Huang H(#), Liu N(#), Zhao K(#), Zhu C, Lu X, Li S, Lian W, Zhou P, Dong X, Zhao C, Guo H, Zhang C, Yang C, Wen G, Lu L, Li X, Guan L, Liu C, Wang X, Dou QP, Liu J(*). Sanggenon C decreases tumor cell viability associated with proteasome inhibition. Frontiers in Bioscience. 2011;3:1315-25.6. 18.Huang H(#), Zhang X(#), Li S(#), Liu N(#), Lian W(#), McDowell E, Zhou P, Zhao C, Guo H, Zhang C, Yang C, Wen G, Dong X, Lu L, Ma N, Dong W, Dou QP, Wang X(*), Liu J(*). Physiological levels of ATP negatively regulate proteasome function. Cell Research. 2010;20:1372-85.
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