个人简介

Associate Professor of Chemistry. Diploma, 1999, Swiss Federal Institute of Technology (ETH) Zurich. Ph.D., 2004, Swiss Federal Institute of Technology (ETH) Zurich. Postdoctoral Fellow 2004-2006, University of California, Berkeley and Lawrence Berkeley National Laboratory. Biophysical Chemistry. Protein structure and function, biological membranes, nuclear magnetic resonance (NMR), NMR methodology.

研究领域

Bioorganic Chemistry/Bioanalytical Chemistry/Molecular Structure/Spectroscopy and Dynamics

Membrane Biochemistry and Biophysics Nuclear Magnetic Resonance (NMR) and Hyperpolarization Structure and Functional Mechanisms of Membrane Proteins

近期论文

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Hwang, S., Shao, Q., Williams, H., Hilty, C. and Gao, Y.-Q. Methanol Strengthens Hydrogen Bonds and Weakens Hydrophobic Interactions in Proteins - A Combined Molecular Dynamics and NMR study. Journal of Physical Chemistry B, 115 (20):6653-6660 (2011). Hwang, S. and Hilty, C. Folding determinants of disulfide bond forming protein B explored by solution NMR Spectroscopy. Proteins-Structure Function and Bioinformatics 79 (5):1365-1375 (2011). Chen, H.-Y., Lee, Y., Bowen, S. andHilty, C. Spontaneous emission of NMR signals in hyperpolarized proton spin systems. Journal of Magnetic Resonance 208 (2): 204-209 (2011). Zeng, H., Lee, Y. and Hilty, C. Quantitative rate determination by DNP enhanced NMR of a Diels-Alder reaction. Analytical Chemistry 82 (21): 8897-8902 (2010). Hilty, C. and Bowen, S. Applications of dynamic nuclear polarization to the study of reactions and reagents in organic and biomolecular chemistry. Organic and Biomolecular Chemistry 8 (15): 3361-3365 (2010). Bowen, S., Hilty, C. Rapid sample injection for hyperpolarized NMR spectroscopy Physical Chemistry Chemical Physics 12 (22): 5766-5770 (2010). Bowen, S., Hilty, C. Temporal chemical shift correlations in reactions studied by hyperpolarized NMR. Analytical Chemistry 81 (11): 4543-4547 (2009). Lee, D., Walter, K. F. A., Brückner, A.-K., Hilty, C., Becker, S., Griesinger, C. Bilayer in Small Bicelles Revealed by Lipid?Protein Interactions Using NMR Spectroscopy. Journal of the American Chemical Society 130 (42): 13822-13823 (2008). Bowen, S., Zeng, H., Hilty, C. Chemical Shift Correlations from Hyperpolarized NMR by Off-Resonance Decoupling. Analytical Chemistry 80 (15): 5794-5798 (2008). Bowen, S., Hilty, C. Time-resolved dynamic nuclear polarization enhanced NMR Spectroscopy. Angewandte Chemie International Edition 47 (28): 5235-5237 (2008).