个人简介

Rachal Professor of Chemistry. B. S., 1979, University of Bath. M. S., 1980, University of East Anglia. Ph. D., 1983, Cambridge University. Postdoctoral Fellow, 1984, University of Wisconsin. Research Fellow, 1985-87, Cambridge University. Organic synthesis and biomedicinal chemistry. Design and synthesis of small molecules to perturb protein-protein interaction. Targeting tumors and healthy cells using molecules designed to interact with cell surface receptors for imaging and chemotherapeutic applications. Dyes for intracellular imaging. Asymmetric catalysis and peptidomimetic chemistry.

研究领域

Bioorganic Chemistry/Synthesis

Design and synthesis of new fluorescent dyes Organic and combinatorial methodologies Preparation of medicinally relevant compounds

近期论文

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Water-soluble Through-bond Energy Transfer Cassettes in Intracellular Imaging, Bandichhor, R.: Petrescu, A. D.: Vespa, A.; Kier, A. B.; Schroeder, F.; Burgess, K.; J. Am. Chem. Soc., 2006, 128, 10688. Heterovalent Selectivity and The Combinatorial Advantage, Burgess, K.; Reyes, S. J.; Chem. Soc. Rev., 2006, 35, 416-23. Ring Closure to β-Turn Mimics via Copper Catalyzed Azide/Alkyne Cycloadditions, Li, Y,; Burgess, K.; J. Org. Chem., 2006, 70, 9595-98. Mechanistic Insights into Iridium-Catalyzed Asymmetric Hydrogenations of Dienes, Cui, X.; Fan, Y.; Hall, M. B.; Burgess, K., Chem. Eur. J., 2005, 11, 6859-68.