研究领域
药物合成化学
以大黄素为原料合成大黄素衍生物，进行抗癌药物分子设计。设计特点：依据抗癌原理，设计能提高大黄素活性氧产生能力和水溶性的大黄素衍生物，然后请精通生物化学和药理学的老师进行药学活性测试和抗癌机制研究
近期论文
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Synthesis and biological activity evaluation of emodin quaternary ammonium salt derivatives as potential anticancer agents, European Journal of Medicinal Chemistry,2012, 56: 320-331.(first author)
Synthesis and antitumor activity of emodin quaternary ammonium salt derivatives ,European Journal of Medicinal Chemistry,2012, 56: 308-319（Corresponding author）
The orbital interaction of adsorbed CO on NiO (001;111) surface: A periodic density functional theory study,Applied Surface Science 2006, 252: 2673-2683.(first author)
A B3LYP study for the adsorption and catalytic ability of BF3 on NiO(001) surface, Journal of Fluorine Chemistry,2005,126: 1463-1466.(first author)
A synthesis of ferrocenyl dihydrocoumarin and ferrocenyl dihydroquinolin-2(1H)-ones, Arkivoc, 2011, xi:105-120. (first author)
W.F. Wang, F.S. Zhang, W.N. Zhao, Z.D. Bai, H.J. Yang, J.W. Shao, Y.F. Yuan, Med. Chem. 9 (2013) 545-552.
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