吴再生 - 福州大学

个人简介

2002年－2005年，湖南大学，分析化学硕士（转直博） 2005年－2008年，湖南大学，分析化学博士 2006年－2010年，湖南大学，讲师，化学生物传感与计量学国家重点实验室固定成员 2010年－2013年，加拿大麦克马斯特大学，Michael G. DeGroote 国际人才重点专项基金特聘博士后研究员 2013年－2014年，加拿大麦克马斯特大学，生物化学与生物医学系博士后研究员 2014年－至今，福州大学教授、博导，能源与环境光催化国家重点实验室

研究领域

核酸纳米器件；功能核酸探针；化学生物传感；药物分析；恶性肿瘤及其转移的诊断与治疗

近期论文

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Chang Xue, Songbai Zhang, Xin Yu, Shuyao Hu, Yi Lu,* and Zai-Sheng Wu*, Periodically Ordered, Nuclease-Resistant DNA Nanowires Decorated with Cell-Specific Aptamers as Selective Theranostic Agents, Angewandte Chemie International Edition, 2020, 59, 17540-17547 Ran Liu, Songbai Zhang, Ting-Ting Zheng, Yan-Ru Chen, Jing-Ting Wu, and Zai-Sheng Wu*, Intracellular Nonenzymatic In Situ Growth of Three-Dimensional DNA Nanostructures for Imaging Specific Biomolecules in Living Cells, ACS Nano, 2020, 14, 8, 9572–9584 Shuxin Zhang, Chang Chen, Chang Xue, Dingran Chang, Huo Xu, Bruno J. Salena, Yingfu Li* and Zai-Sheng Wu*, Ribbon of DNA Lattice on Gold Nanoparticles for Selective Drug Delivery to Cancer Cell, Angewandte Chemie International Edition, 2020, 59(34), 14584-14592 Changhe Ouyang, Songbai Zhang, Chang Xue, Xin Yu, HuoXu, Zhenmeng Wang, Yi Lu,* and Zai-Sheng Wu*, Precision guided missile-like DNA nanostructure containing warhead and guidance control for aptamer-based targeted drug delivery into cancer cells in vitro and in vivo, Journal of the American Chemical Society, 2020, 142, 3, 1265-1277 Yansha Gao, Qian Li, Jingjing Zhang, Chengwei Wu, Zhifa Shen, Chang Xue, Huan-Tsung Chang,* and Zai-Sheng Wu,* Bead-String-Shaped DNA Nanowires with Intrinsic Structural Advantages and Its Potential for Biomedical Applications, ACS Applied Materials & Interfaces, 2020, 12, 3, 3341-3353 Congcong Li, Chang Xue, Jue Wang, Mengxue Luo, Zhifa Shen and Zai-Sheng Wu*, Oriented tetrahedron-mediated protection of catalytic DNA molecular-scale detector against in vivo degradation for intracellular miRNA detection, Analytical Chemistry, 2019, 91(18), 11529-11536 Chang Xue, Shu-Xin Zhang, Chang-He Ouyang, Dingran Chang, Bruno J. Salena, Yingfu Li* and Zai-Sheng Wu*, Target-induced Catalytic Assembly of Y-Shaped DNA and Its Application for In Situ Imaging of MicroRNAs, Angewandte Chemie International Edition, 2018, 57, 9739–9743, IF = 12.257 Zhe Yang, Songbai Zhang, Hui Zhao, Huimin Niu, Zai-Sheng Wu* and Huan-Tsung Chang, Branched DNA junction-enhanced isothermal circular strand displacement polymerization for intracellular imaging of microRNAs, Analytical Chemistry, 2018, 90(23), 13891–13899 Zhi-Fa Shen, Feng Li, Yi-Fan Jiang, Chang Chen, Huo Xu, Cong-Cong Li, Zhe Yang and Zai-Sheng Wu,* Palindromic molecule beacon-based cascade amplification for colorimetric detection of cancer genes, Analytical Chemistry, 2018, 90(5), 3335-3340 Zai-Sheng Wu, Zhifa Shen, Kha Tram, Yingfu Li,* Engineering interlocking DNA rings with weak physical interactions. Nature Communications, 2014, 5, 4279