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个人简介

指导药物化学、药剂学、物理化学和生物化工专业的硕士生和博士生论文工作。指导制药工程专业和化学专业本科生的毕业论文工作。承担多项校级和省级教改项目。指导多组本科生获国家和省级大学生创新创业训练计划项目资助,所指导的项目多次获优秀结题项目奖励。指导学生并带队参加2016年度全国创新创业大赛,获第五届中国创新创业大赛(福建赛区)暨第四届福建创新创业大赛二等奖,入围全国总决赛并获全国第五届中国创新创业大赛优秀团队奖。 曾获福州大学教学名师和宝钢优秀教师奖。曾作为第一完成人获福州大学教学优秀奖一等奖、福州大学教学成果特等奖、福建省教学成果二等奖和中国学位与研究生教育学会研究生教育成果奖二等奖等教学奖励。

研究领域

(1)医用光敏剂与光动力治疗、医用声敏剂与声动力治疗 (2)抗癌抗真菌化合物及其新剂型 (3)海洋生物活性物质利用技术 (4)功能酞菁衍生物的合成及性能研究

近期论文

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Bing-De Zheng, Qin-Xue He, Xingshu Li*, JuyoungYoon*, Jian-Dong Huang*, Phthalocyanines as contrast agents for photothermal therapy, Coordination Chemistry Reviews, 2021, 426(1): 213548. DOI: 10.1016/j.ccr.2020.213548. Dong-Hua Wan, Xin-Yue Ma, Chen Lin, Deng-Hui Zhu, Xingshu Li, Bi-Yuan Zheng, Jinyu Li, Mei-Rong Ke and Jian-Dong Huang*, The Non-Covalent Indocyanine Green Conjugate of C-Phycocyanin: Preparation and Tumor-Associated Macrophages-Targeted Photothermal Therapeutics. Bioconjugate Chemistry, 2020, 31(5): 1438–1448. DOI: 10.1021/acs.bioconjchem.0c00139. Xingshu Li, Sungsook Yu, Yoonji Lee, Tian Guo, Nahyun Kwon, Dayoung Lee, Su Cheong Yeom, Yejin Cho, Gyoungmi Kim, Jian-Dong Huang*, Sun Choi*, Ki Taek Nam*, and Juyoung Yoon*, In Vivo Albumin Traps Photosensitizer Monomers from Self-Assembled Phthalocyanine Nanovesicles: A Facile and Switchable Theranostic Approach, Journal of the American Chemical Society, 2019, 141(3): 1366-1372. DOI: 10.1021/jacs.8b12167. Xingshu Li, Dayoung Lee, Jian-Dong Huang*, Juyoung Yoon*, Phthalocyanine-Assembled Nanodots as Photosensitizers for Highly Efficient Type I Photoreactions in PDT, Angewandte Chemie International Edition, 2018, 57: 9885-9890. DOI: 10.1002/ange.201806551. Bi-Yuan Zheng, Xiao-Qin Yang, Yang Zhao, Qiao-Feng Zheng, Mei-Rong Ke, Tao Lin, Ren-Xun Chen, Kitty K.K. Ho, Naresh Kumar, Jian-Dong Huang*, Synthesis and photodynamic activities of integrin-targeting silicon(IV) phthalocyanine-cRGD conjugates, European Journal of Medicinal Chemistry, 2018, 155: 24-33. DOI: 10.1016/j.ejmech.2018.05.039. Xu-Dong Ren, Xiu-Yun Hao, Hong-Cai Li, Mei-Rong Ke, Bi-Yuan Zheng, Jian-Dong Huang*, Progress in the development of nanosensitizers for X-ray-induced photodynamic therapy, Drug Discovery Today, 2018, 23(10): 1791-1800. DOI: 10.1016/j.drudis.2018.05.029. Xingshu Li, Xiao-Hui Peng, Bing-De Zheng, Jilin Tang, Yuanyuan Zhao, Bi-Yuan Zheng, Mei-Rong Ke, Jian-Dong Huang*, New application of phthalocyanine molecules: from photodynamic therapy to photothermal therapy by means of structural regulation rather than formation of aggregates, Chemistry Science, 2018, 9: 2098-2104. DOI: 10.1039/C7SC05115H. Dong-Hua Wan, Bi-Yuan, Zheng, Mei-Rong Ke, Ji-Ying Duan, Zheng Yun-Quan, Chih-Kuang Yeh, Jian-Dong Huang*, C-Phycocyanin as a tumour-associated macrophage-targeted photosensitiser and vehicle of phthalocyanine for enhanced photodynamic therapy, Chem. Commun., 2017, 53: 4112-4115. DOI: 10.1039/c6cc09541k. Xing-Shu Li, Mei-Rong Ke, Miao-Fen Zhang, Qing-Qing Tang, Bi-Yuan Zheng,Jian-Dong Huang*, A non-aggregated and tumour-associated macrophage-targeted photosensitiser for photodynamic therapy: A novel zinc(II) phthalocyanine containing octa-sulphonates,Chem. Commun. 2015, 51: 4704-4707. DOI: 10.1039/C4CC09934F. Hai-Jun Chen, Xiu-Rong Huang, Xiao-Bin Zhou, Bi-Yuan Zheng, Jian-Dong Huang*, Potential sonodynamic anticancer activities of artemether and the liposome–encapsulated artemether, Chem. Commun. 2015, 51: 4681-4684. DOI: 10.1039/C5CC00927H.

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