郑宜 - 福州大学 - 化学学院

研究领域

辐射生物化学、光催化长期从事超高真空表面及结构、辐射生物、光催化在医学和生物领域的基础与应用研究。尤其专业于低能电子和辐射生物化学等领域，擅长运用色谱、质谱等化学分析手段。近几年来，主要开展低能电子对DNA损伤和生物光催化的研究。

近期论文

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Xiaobin Yao, Chuanna Huang, Xiaoping Chen, Yi Zheng,* Leon Sanche, Chemical radiosensitivity of DNA induced by gold nanoparticles, J. Biomed. Nanotechnol. 11(3), 478-485 (2015). Qianhong Bao, Yunfeng Chen, Yi Zheng,* Léon Sanche, Cisplatin radiosensitization of DNA irradiated with 2-20 eV electrons: role of transient anions, J. Chem. Phys. C 118, 15516 (2014). Xinglan Luo, Yi Zheng,* Léon Sanche, DNA strand breaks and crosslinks induced by transient anions in the electron-energy range 2-20 eV, J. Chem. Phys. 140, 155101 (2014). Fangxing Xiao, Xinglan Luo, Xianzhi Fu, Yi Zheng*, Cleavage enhancement of specific chemical bonds in DNA by Cisplatin Radiosensitization, J. Phys. Chem. B 117, 4893-4900 (2013). Yi Zheng, Léon Sanche, Low energy electrons in nanoscale radiation physics: relationship to radiosensitization and chemoradiation therapy, Rev. Nanoscience & Nanotechnology 2,1-28(2013). Chuanna Huang, Qianhong Bao, Darel Hunting, Yi Zheng*, Léon Sanche, Conformation-dependent DNA damage induced by gold nanoparticles, J. Biomed. Nanotechnol. 9, 856-862 (2013). Fangxing Xiao, Xiaobin Yao, Qianhong Bao, Danzhen Li, Yi Zheng*, Sensitive marker of the cisplatin-DNA interaction: X-ray photoelectron spectroscopy of Cl, Bioinorganic Chem. Appli. 649640 (2012). A facile and green self-assembly preparation of gold nanoparticles/ZnO nanocomposite for photocatalytic and photoelectrochemical applications J. Mater. Chem. 22, 2868 (2012). On the role of low-energy electrons in the radiosensitization of DNA by gold nanoparticles Nanotechnology, 22, 465101 (2011). Influence of organic ions on DNA damage induced by 1 eV to 60 keV electrons J. Chem. Phys., 133, 155102 (2010). Protection by organic ions against DNA damage induced by low energy electrons J. Chem. Phys., 132, 045102 (2010). Gold nanoparticles enhance DNA damage induced by anti-cancer drugs and radiation Radiation Research, 172, 114-119 (2009). Radiosensitization by gold nanoparticles: Comparison of DNA damage induced by low and high-energy electrons J. Biomedical Nanotechnology, 4(4), 469-473 (2008). Role of secondary low-energy electrons in concomitant chemoradiation therapy of cancer Phys. Rev. Lett., 100, 198101-4 (2008). Low Energy Electron Induced DNA Damage: Effects of Terminal Phosphate and Base Moieties on the Distribution of Damage J. Am. Chem. Soc., 130, 5612-5613 (2008). Radiosensitization of DNA by gold nanoparticles irradiated with high-energy electrons Radiation Research, 169, 19-27 (2008). DNA damage induced by low-energy electrons: electron transfer and diffraction Phys. Rev. Lett., 96, 208101 (2006). Phosphodiester and N-glycosidic bond cleavage in DNA induced by 4-15 eV electrons J. Chem. Phys., 124, 064710 (2006). Chemical basis of DNA sugar-phosphate cleavage induced by low-energy electrons J. Am. Chem. Soc., 127, 16592-16598 (2005). Irradiator to Study damage induced to large nonvolatile molecules by Low-energy Electrons Review of Scientific Instruments, 75, 4534 (2004). Glycosidic N-bond cleavage of thymidine induced by low energy electrons J. Am. Chem. Soc., 126, 1002 (2004).