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生物酶催化制备手性化合物,功能染料设计与合成 1)生物酶催化合成有机化学 2)芳香杂环化学和光化学

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Zn2+-Triggered Amide Tautomerization Produces a Highly Zn2+-Selective, Cell-Permeable, and Ratiometric Fluorescent SensorZhaochao Xu,* Kyung-Hwa Baek, Ha Na Kim, Jingnan Cui, Xuhong Qian, David R. Spring, Injae Shin,* ,Juyoung Yoon*J. Am. Chem. Soc. 2010, 132, 601. A new class of organic dyes based on acenaphthopyrazine for dye-sensitized solar cells, Z. Kong, H. Zhou, J. Cui, T. Ma, X. Yang, L. Sun, J. Photochem. Photobio. A: Chem. 2010, 213, 152-157. Preparation of chiral trans-5-substituted-acenaphthene-1,2-diols by baker’s yeast-mediated reduction of 5-substituted-acenaphthylene-1,2-diones, L. Wang, X. Wang, J. Cui, W. Ren, N. Meng, X. Qian, Tetrahedron: Asymmetry, 2010, 21, 825-830. Design, Synthesis and Bioactivity of Vinylnitro-cyano Neonicotinoids as Potential Insecticides,K. Wang, X. Qian, J. Cui, Monatsh. Chem. 2010, 141, 1117. One step from nitro to oxime: a convenient preparation of unsaturated oximes by the reduction of the corresponding vinylnitro compoundsKewei Wang, Jingnan Cui, Xuhong Qian,*Tetrahedron, 2009, 65, 10377. Lijuan Xie, Yi Xiao, Fang Wang, Yufang Xu, Xuhong Qian,* Rong Zhang, Jingnan Cui,* Jianwen Liu*Novel acenaphtho[1,2-b]pyrrole-carboxylic acid family: synthesis, cytotoxicity, DNA-binding and cell cycle evaluationBioorg. Med. Chem. 2009, 17, 7615. Lijuan Xie, Yufang Xu, Fang Wang, Jianwen Liu, Xuhong Qian,* Jingnan Cui *Synthesis of new amonafide analogues via coupling reaction and their cytotoxic evaluation and DNA-binding studiesBioorg. Med. Chem. 2009, 17, 804. Lijuan Xie, Xuhong Qian,* Jingnan Cui,* Yi Xiao, Kewei Wang, Peichun Wu, Liying CongNovel Angular Furoquinolinones Bearing Flexible Chains as Antitumor Agents: Synthesis, Cytotoxic Evaluation and DNA-Binding StudiesBioorg. Med. Chem. 2008, 16, 8713. Chunliang Lu, Zhaochao Xu, Jingnan Cui,* Rong Zhang, Xuhong Qian;* A Ratiometric and Highly Selective Fluorescent Sensor for Cadmium under Physiological pH Range: a New Strategy to Discriminate Cadmium from ZincJ. Org. Chem. 2007, 72,3554-3557. Feng Li, Jingnan Cui,* Lianying Guo, Xuhong Qian,* Weimin Ren, Kewei Wang, Fengyu Liu,Molecular design, chemical synthesis, and biological evaluation of ‘4-1’ pentacyclic arylimidazonaphthalimidesBoorg. Med. Chem. 2007, 15, 5114-51221. Feng Li, Jingnan Cui,* Xuhong Qian,* Weimin Ren, Xingyong WangBaker’s yeast-mediated enantioselective reduction of substituted fluorenonesChem. Commun., 2006, 865-867. Zhaochao Xu, Xuhong Qian,* Jingnan Cui,* Rong Zhang Exploiting the deprotonation mechanism for the design of ratiometric and colorimetric Zn2+ fluorescent chemosensor with a large red-shift in emissionTetrahedron, 2006, 62, 100117-10122. Jiaobing Wang, Xuhong Qian,* Jingnan CuiDetecting Hg2+ ions with an ICT fluorescent sensor molecule: Remarkable emission spectra shift and unique selectivityJ. Org. Chem. 2006, 71, 4308-4311. Feng Li, Jingnan Cui,* Xuhong Qian,* Rong Zhang, Yi Xiao, Highly chemoselective reduction of aromatic nitro compounds to the corresponding hydroxylamines catalysed by plant cells from grape (Vitis vinifera L.),Chem. Commun., 2005, 1901-1903. Zhaochao Xu, Xuhong Qian,* Jingnan Cui,*A Colorimetric and Ratiometric Fluorescent Chemosensor With a Large Red-shift in Emission: Cu(II)-Only Sensing by Deprotonation of Secondary Amines as Receptor Conjugated to Naphthalimide FluorophoreOrg. Lett. 2005, 3029-3032. Zhaochao Xu, Yi Xiao, Xuhong Qian,* Jingnan Cui,* Dawei Cui,A Ratiometric and Selective Fluorescent Sensor for CuII Based on Internal Charge Transfer (ICT)Org. Lett. 2005, 889-892. Yi Xiao, Fengyu Liu, Xuhong Qian,* Jingnan Cui, A New Class of Long-Wavelength Fluorophores: Strong Red Fluorescence, Convenient Synthesis and Easy Derivation,Chem. Commun. 2005, 239-241. Feng Li, Jingnan Cui,* Xuhong Qian,* Rong Zhang, A novel strategy for the preparation of arylhydroxylamines: chemoselective reduction of aromatic nitro compounds using bakers’ yeast,Chem. Commun., 2004, 2338-2339.

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