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个人简介

教育经历 1964.91968.8 大连辽宁师范学院附属中学无 1987.41999.12 日本富山医科药科大学药学博士 1973.91976.10 沈阳药学院药学学士 工作经历 2000.8至今 大连理工大学 1980.122000.8 大连市医药科学研究所药师 1978.51980.11 大连市药品检验所药师 1976.111978.4 鞍山市职业病医院药师

研究领域

药物化学与天然有机化学;转化医学与替代医学研究;医药品生产过程质量控制与保证 心脑血管、肝代谢疾病治疗药物,抗肿瘤、病毒活性先导化合物,抗衰老活性化合物的发现、设计、计算、合成、构效关系与生物活性评价研究: 1、生物活性天然化合物的全合成 2、天然生物活性物质的药物化学应用 3、转化医学的新物质与新方法 4、医药品生产的在线分析研究

近期论文

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Deng, Jiu,Wei, Wenbo,Chen, Zongzheng,Lin, Bingcheng,Zhao, Weijie,Luo, Yong,Zhang, Xiuli.Engineered Liver-On-A-Chip Platform to Mimic Liver Functions and Its Biomedical Applications: A...[J],MICROMACHINES,2019,10(10) Li Yue-Qing,Li Guang-Zhe,Dong Yi,Ma Xu,Dong Hui-Juan,Wu Qian-Qian,Zhao Wei-Jie.Orobanoneanaloguesfromacid-promotedaromatizationrearrangementof curcumolinhibithypoxia-induciblef...[J],Bioorganic Chemistry,2019,85:357-363 李悦青,吴茜茜,宋其玲,曹雷,秦秋燕,徐艳,赵伟杰.肉桂酰酪胺类似物的合成与抗血小板聚集评价[J],应用化学,2018,35(10):1174-1183 Gao, Zhigang,Qu, Yueyang,Xu, Lingling,Luo, Yong,Lu, Yao,Liu, Tingjiao,Zhao, Weijie,Chen, Zongzheng,Deng, Jiu,Li, Xiaorui,Lin, Bingcheng.Measurement of Carcinoembryonic Antigen in Clinical Serum Samples Using a Centrifugal Microflui...[J],MICROMACHINES,2018,9(9) 曲玥阳,陈旭,岳喜庆,罗勇,赵伟杰,林炳承.原代肾小管上皮细胞的提取和培养方法的优化[J],沈阳农业大学学报,2018,49(1):27-33 Guo, Xiuhan,Cai, Rui,Wang, Shisheng,Tang, Bo,Li, Yueqing,Zhao, Weijie.Non-destructive geographical traceability of sea cucumber (Apostichopus japonicus) using near i...[J],ROYAL SOCIETY OPEN SCIENCE,2018,5(1):170714 Cao, Lei,Guo, Xiuhan,Wang, Liu,Wang, Shisheng,Li, Yueqing,Zhao, Weijie.Synthesis and in vitro phototoxicity of novel pi-extension derivatives of chlorin e6[J],NEW JOURNAL OF CHEMISTRY,2017,41(23):14279-14287 Guo, Xiuhan,Wang, Liu,Li, Yueqing,Cao, Lei,Cai, Rui,Zhao, Weijie,Wang, Shisheng.Synergistic antiproliferative effect of chemo-phototherapy: Synthesis and photodynamic activity...[J],BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2017,27(19):4548-4551 Zhang, Ge,Guo, Xiu-Han,Wang, Shi-Sheng,Li, Yue-Qing,Li, Guang-Zhe,Zhao, Wei-Jie.Screening and identification of natural ligands of tyrosinase from Pueraria lobata Ohwi by a co...[J],ANALYTICAL METHODS,2017,9(33):4858-4862 王世盛,高志刚,郭修晗,孟庆伟,汪晴,赵伟杰.工程教育认证背景下的制药工程专业生产实习[J],化工高等教育,2017,34(4):81-84 高志刚,林炳承,郑婷婷,邓九,李晓瑞,曲玥阳,陆瑶,刘婷娇,罗勇,赵伟杰.基于便携拉曼光谱仪和双层纸芯片的头发皮质醇超高灵敏检测[J],化学学报,2017,75(4):355-359 Wu, Sijin,Hu, Qiwan,Yang, Yongliang,Luo , Huizhe,Wang, Haina,Zhao, Weijie.Cysteinome: The first comprehensive database for proteins with targetable cysteine and their co...[J],BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2016,478(3):1268-1273 李悦青,吴茜茜,宋其玲,徐艳,秦秋燕,赵伟杰.柄果花椒酰胺及类似物的合成与抗血小板聚集活性评价[A],2016,1 Cao, Zhi,Li, Yueqing,Wang, Shisheng,Tang, Bo,Guo, Xiuhan,Wang, Liu,Zhao, Weijie.Biomimetic synthesis of bis-alpha-substituent pyrrolidine alkaloids based on a proposed biosynt...[J],TETRAHEDRON LETTERS,2016,57(21):2219-2221 An, Fan,Qu, Yueyang,Luo, Yong,Fang, Ning,Liu, Yang,Gao, Zhigang,Zhao, Weijie,Lin, Bingcheng.A Laminated Microfluidic Device for Comprehensive Preclinical Testing in the Drug ADME Process[J],SCIENTIFIC REPORTS,2016,6:25022 Li, Yue-qing,Yang, Fei,Wang, Liu,Cao, Zhi,Han, Tian-jiao,Duan, Zhe-ang,Li, Zhen,Zhao, Wei-jie.Phosphoramidate protides of five flavones and their antiproliferative activity against HepG2 an...[J],EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,2016,112:196-208 Wang, Ying-Qun,Wang, Shi-Sheng,Zhu, Ji,Wang, Lei,Jiang, Bo-Hai,Zhao, Wei-Jie.Determination of urea content in urea cream by centrifugal partition chromatography[J],JOURNAL OF FOOD AND DRUG ANALYSIS,2016,24(2):399-405 Zou, Kun,Gao, Zhigang,Deng, Quanfeng,Luo, Yong,Zou, Lijuan,Lu, Yao,Zhao, Weijie,Lin, Bingcheng.Picomolar detection of carcinoembryonic antigen in whole blood using microfluidics and surface-...[J],ELECTROPHORESIS,2016,37(5-6):786-789 高志刚,王世盛,宋其玲,赵伟杰.制药工程人才培养模式改革与实践[J],药学教育,2016,1:18-21,52 Zheng, Tingting,Gao, Zhigang,Luo, Yong,Liu, Xianming,Zhao, Weijie,Lin, Bingcheng.Manual-slide-engaged paper chip for parallel SERS-immunoassay measurement of clenbuterol from s...[J],ELECTROPHORESIS,2016,37(3,SI):418-424

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