刘田 - 大连理工大学 - 生物工程学院

个人简介

刘田，教授，博士生导师。入选国家级青年人才计划、省高等学校优秀人才支持计划及校星海优青人才培养计划。曾在Matter、ACS Nano、Biotechnol. Adv.、Cell Rep. Phys. Sci.及J. Agric. Food Chem.等SCI期刊发表论文60余篇，近5年他引>1200次，h-index>25。担任Curr. Med. Chem.、Front. Mol. Biosci.及Heliyon等SCI期刊副主编或编委，《农药学学报》青年编委会副主任。主持国家自然科学基金(3项)、国家重点研发计划子课题(3项)及Bayer公司Grants4Ag 2023等项目。曾获第13届国际生物技术大会青年科学家奖及首届大连市青年科技之星等荣誉。课题组拥有先进的设备平台及友爱的科研氛围，擅长技术包括蛋白质表达纯化、蛋白质结构解析、蛋白质理性设计、药物筛选与设计、生物材料表征、组学分析、基因沉默及表型分析等。课题组与新加坡南洋理工大学 (生物材料)、中国科学与技术大学 (结构生物学)及中粮营养健康研究院(酶制剂应用)等单位保持密切合作关系

研究领域

农业病虫害防治新靶标的发现及应用绿色农药先导分子的筛选及结构改造新颖仿生材料的设计与应用新生物高聚物降解酶的研发

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Qi, H., Teng, Y., Chen, S., Yuan, F., Chen, L., Liang, X., Yang, Q.* & Liu, T.* (2024). Major structural protein in locust mandible capable of forming extraordinarily stiff materials via hierarchical self-assembly. Matter, 7, 1-16. IF=18.9 Qi, H., Ding, Y., Teng, Y., Liang, X., Chen, L., Ma, J., Yang, Q.* & Liu, T.* (2023). A core structural protein that builds the locust mandible with a mechanical gradient. ACS Nano, 17(24), 25311-25321. IF=17.1 Gong, Q., Liu, B., Yuan, F., Tao, R., Huang, Y., Zeng, X., Wang, J.*, Liu T.* & Zhang, G.* (2023). Controllably self-assembled antibacterial nanofibrils based on insect cuticle protein for infectious wound healing. ACS Nano, 17(23), 23679-23691. IF=17.1 Liu, T., Duan, Y., & Yang, Q.* (2018). Revisiting glycoside hydrolase family 20 β-N-acetyl-D-hexosaminidases: crystal structures, physiological substrates and specific inhibitors. Biotechnol. Adv., 36(4), 1127-1138. IF=16.0 Liu, W., Yuan, F., Wang, J., Qin, C., Pang, Z., Teng, Y., Li, F. & Liu, T.* (2023). Simultaneous lice eggshell removal from wool and anti-felting with a single protease treatment. J. Clean. Prod., 386, 135828. IF=11.1 Dong Yawen,Hu Song,Jiang Xi,Liu Tian,Ling Yun,He Xiongkui,Yang Qing,Zhang Li.Pocket-based Lead Optimization Strategy for the Design and Synthesis of Chitinase Inhibitors[J],Journal of agricultural and food chemistry,2019 Duan, Yanwei,Liu, Tian,Zhou, Yong,Dou, Tongyi,Yang, Qing.Glycoside hydrolase family 18 and 20 enzymes are novel targets of the traditional medicine berb...[J],JOURNAL OF BIOLOGICAL CHEMISTRY,2018,293(40):15429-15438 Dong, Yawen,Jiang, Xi,Liu, Tian,Ling, Yun,Yang, Qing,Zhang, Li,He, Xiongkui.Structure-Based Virtual Screening, Compound Synthesis, and Bioassay for the Design of Chitinase...[J],JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2018,66(13):3351-3357 Liu, Tian,Duan, Yanwei,Yang, Qing.Revisiting glycoside hydrolase family 20 beta-N-acetyl-d-hexosaminidases: Crystal structures, phy...[J],Biotechnology advances,2018,36(4):1127-1138 Liu, Tian,Zhu, Weixing,Wang, Jing,Zhou, Yong,Duan, Yanwei,Qu, Mingbo,Yang, Qing.The deduced role of a chitinase containing two nonsynergistic catalytic domains[J],ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY,2018,74(Pt 1):30-40 Chen, Lei,Liu, Tian,Duan, Yanwei,Lu, Xinhua,Yang, Qing.Microbial Secondary Metabolite, Phlegmacin B-1, as a Novel Inhibitor of Insect Chitinolytic Enz...[J],JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2017,65(19):3851-3857 刘田,杨青.Structural determinants of an insect β-N-acetyl-D-hexosaminidase specialized as a chitinolytic e...[J],JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286:4049-4058.,2011,286(1):4049-4058 刘田（并列）, Q.,Yang, X., Shen, Q., Chen, Y., Zhou, T., Liu, L.,Chen.Structural characteristics of an insect group I chitinase, an enzyme indispensable to moulting,Acta Crystallographica Section D-Structural Biology,2014,70:932-942 刘田, Q.,Yang, Y., Duan, X., Jiang, Y., Zhou, L., Chen, T.,Liu.Structure, catalysis and inhibition of OfChi-h, the Lepidoptera-exclusive insect chitinase[J],Journal of Biological Chemistry,2017,292:2080-2088 朱卫星（研究生）.Production of N-acetyl-D-glucosamine from mycelial waste by a combination of bacterial chitinases...[J],Journal of Agricultural and Food Chemistry,2016,64:6738-6744 陈磊（研究生）.The microbial secondary metabolite, phlegmacin B1, as a novel inhibitor of insect chitinolytic en...[J],Journal of Agricultural and Food Chemistry,2017,65:3851-3587