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真核生物信号转导通路,蛋白相互作用,抗癌小分子化合物,药物机理

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A MAP Kinase Dependent Feedback Mechanism Controls Rho1 GTPase and Actin Distribution in Yeast Rheb Activates mTOR by Antagonizing Its Endogenous Inhibitor, FKBP38. Science 318, 977 (2007) Xiaochun Bai, Dongzhu Ma, Anling Liu, Xiaoyun Shen, et al Rapamycin activates Tap42-associated phosphatases by abrogating their association with Tor complex 1 Cyclin-dependent kinase 11 interacts with HBO1 and enhances its histone acetyltransferase activity Cyclin D3 interacts with human activating transcription factor 5 and potentiates its transcription activity Identification of the p28 subunit of eukaryotic initiation factor 3(eIF3k) as a new interaction partner of cyclin D3 Trihydrophobin 1 Is a New Negative Regulator of A-Raf Kinase* The h-(1!6)-branched h-(1!3) glucohexaose and its analogues containing an a-(1!3)-linked bond have similar stimulatory effects on the mouse spleen as Lentinan

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