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研究领域

1.卵黄免疫球蛋白(IgY)替代抗生素的研究 2、海珍品——刺参集约化健康养殖关键技术研究 3.高效利用天然活性物质的微切变-助剂互作技术的研究与应用 4.噬菌体技术控制动物细菌性疾病的研究 5. 堆肥法治理养殖业废弃物专用微生物制剂研究

近期论文

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Li J.G., Xu Y.P.*, Jin L.J., Li X.Y. Effects of the probiotics mixture (Bacillus subtilis YB-1 and Bacillus cereus YB-2) on disease resistance and non-specific immune responses of sea cucumber (Apostichopus japonicus Selenka). Aquaculture Research. (in press) Zhang J.C., Cao Z.H., Jin L.J., Li Z., Li X.Y., Li H.Q., Wu F.F., Cao F., Li S.Y., Wang L.L., Xu Y.P.* Effect of Bacteriophages on Vibrio alginolyticus Infection in the Sea Cucumber, Apostichopus japonicus (Selenka). Journal of World Aquaculture Society. (in press) Cao Z.H., Zhang J.C., Niu Y.D., Cui N.Z., Ma Y.S., Cao F., Jin L.J., Li Z., Xu Y.P.* Isolation and characterization of a “phiKMV-like” bacteriophage and its therapeutic effect on mink hemorrhagic pneumonia. PLoS ONE.(in press) Wang J., Xu Y.P., Li X.Y., Li J.G., Bao P.Y., Che J., Li S.Y., Jin L.J.* Vitamin E requirement of sea cucumber (Apostichopus japonicus) and its' effects on non-specific immune responses. Aquaculture Research. (in press) You J., Y. Xu, H. Li, L. Wang, F. Wu, F. Xu, L. Jin, S. Li, X. Li* (2014) Chicken egg yolk immunoglobulin (IgY) developed against fusion protein LTB–STa–STb neutralizes the toxicity of Escherichia coli heat-stable enterotoxins. Journal of Applied Microbiology. 117(2): 320 - 328. Zhang J.C., Cao Z.H., Xu Y.P., Li X.Y., Li H.Q., Wu F.F., Wang L.L., Cao F., Li Z., Li S.Y., Jin L.J.* (2014) Complete genomic sequence of the Vibrio alginolyticus lytic bacteriophage PVA1. Archives of Virology, 159:12, 3447-3451. Wang X.T., Wang L.L., Che J., Li X.Y., Li J.G., Wang J., Xu Y.P.* (2014) In vitro non-specific immunostimulatory effect of alginate oligosaccarides with different molecular weights and compositions on sea cucumber (Apostichopus japonicus) coelomocytes. Aquaculture. 434: 434-441. Sha Lei, Yongping Xu.* (2013). Effects of fasting and refeeding with different fat supplements on hepatic lipidosis in mink. Indian Journal of Animal Research. 47(6):465-471. Wu F.F., Li H.Q., Zhao L.Z., Li X.Y., You J.S., Jiang Q., Li S.Y., Jin L.J., Xu Y.P.* (2013). Protective effects of aqueous extract from Acanthopanax senticosus against corticosterone-induced neurotoxicity in PC12 cells. Journal of Ethnopharmacology. 148:861-868. Jin L.J., Wu F.F., Li X.Y., Li H.Q., Du C., Jiang Q., You J.S., Li S.Y., Xu Y.P.* (2013) Anti-depressant effects of aqueous extract from Acanthopanax senticosus in mice. Phytotherapy Research. 27:1829-1833. Jiang S.Y., Jiao J., Zhang T.T., Xu Y.P.* (2013). Pharmacokinetics study of recombinant hirudin in the plasma of rats using chromogenic substrate, ELISA, and radioisotope assays. PLoS One.8(6):e64336. Cui N.Z., Xu Y.P., Cao Z.H., Xu F.X., Zhang P., Jin L.J.*. (2013). Effects of heat stress on the level of heat shock protein 70 on the surface of hepatocellular carcinoma Hep G2 cells: implications for the treatment of tumors. Tumor Biology. 34(2):743-748. Wu F.F., Li H.Q., Jin L.J., Li X.Y., Ma Y.S., You J.S., Li S.Y., Xu Y.P.* (2013). Deer antler base as a traditional Chinese medicine: A review of its traditional uses, chemistry and pharmacology. Journal of Ethnopharmacology, 145(2): 403-415. Jin L.J., Li X.Y., Zou D.L., Li S.Y., Song W.Q., Xu Y.P.* (2013). Protection of crucian carp (Carassius auratus Gibelio) against septicaemia caused by Aeromonas hydrophila using specific egg yolk immunoglobulins. Aquaculture Research, 44:928-936. Wang T.T., Sun Y.X., Jin L.J., Thacker P., Li S.Y., Xu Y.P.* (2013). Aj-rel and Aj-p105, two evolutionary conserved NF-κB homologues in sea cucumber (Apostichopus japonicus) and their involvement in LPS induced immunity. Fish & Shellfish Immunology. 34(1):17-22. Li H.Q., Jin L.J., Wu F.F., LI X.Y., You J.S., Cao Z.H., Xu Y.P.* (2012) Effect of curcumin on proliferation, cell cycle, and caspases and MCF-7 cells. African Journal of Pharmacy and Pharmacology. 6(12):864-870. Li H.Q., Jin L.J., Wu F.F., Thacker P., Li X.Y., You J.S., Wang X.Y., Liu S.Z., Li S.Y., Xu Y.P.* (2012). Effect of red pepper (Capsicum frutescens) powder or red pepper pigment on the performance and egg yolk color of laying hens. Asian-Australasian Journal of Animal Sciences. 25(11):1605-1610. Jin L.J., Li H.Q., Wu F.F., Li X.Y., Yu H.B., Cui N.Z., You J.S., Cao Z.H., Sun X.H., Zhang J.C., Wang X.L., Song C.N., Li S.Y., Xu Y.P.* (2012). Application of mechanochemical pretreatment prior to aqueous extraction of Eleutheroside B from Eleutherococcus senticosus. Industrial Engineering Chemistry Research. 51:10695-10701. Li X.Y., Liu H., Xu Y.P., Xu F.X., Wang L.H., You J.S., Li S.Y., Jin L.J.* (2012). Chicken egg yolk antibody (IgY) controls Solobacterium moorei under in vitro and in vivo conditions. Applied Biochemistry and Biotechnology. 168(6):1448-1458. Li X.Y., Xu F.X., Liu H., Liang B., Xu Y.P., Jin L.J.* (2012). Application of polymerase chain reaction (PCR)-based denaturing gradient gel electrophoresis for analysis of microbiota on the tongue dorsa of subjects with halitosis. African Journal of Microbiology Research. 6(28):5789-5795. Xu F.X., Xu Y.P., Jin L.J., Liu H., Wang L.H., You J.S., Li S.Y., Li X.Y.*(2012). Effectiveness of egg yolk immunoglobulin (IgY) against periodontal disease-causing Fusobacterium nucleatum. Journal of Applied Microbiology. 113(4):983-991. Xue H.Y., Lu Y.N., Fang X.M., Xu Y.P., Gao G.Z., Jin L.J.*. (2012). Neuroprotective properties of aucubin in diabetic rats and diabetic encephalopathy rats. Molecular Biology Reports. 39(10):9311-9318. Ma Y.S., Pacan J.C., Wang Q., Sabour P.M.*, Huang X.Q., Xu Y.P. (2012). Enhanced alginate microspheres as means of oral delivery of bacteriophage for reducing Staphylococcus aureus intestinal carriage. Food Hydrocolloids, 26(2): 434-440. Zhen Y.H., Fang R., Ding C., Jin L.J., Li X.Y., Diao Y.P., Shu X.H., Ma X.C., Xu Y.P.* (2011). Efficacy of specific IgY for treatment of lipopolysaccharide-induced endotoxemia using a mouse model. Journal of Applied Microbiology, 111(6): 1524-1532. You J.S.,Xu Y.P., He M., McAllister T.A., Thacker P.A., Li X.Y., Wang T.T., Jin L.J.* (2011). Protection of mice against enterotoxigenic E. coli by immunization with a polyvalent enterotoxin comprising a combination of LTB, STa, and STb. Applied Microbiology and Biotechnology, 89(6): 1885-1893. Xue H.Y., Niu D.Y., Gao G.Z., Lin Q.Y., Jin L.J., Xu Y.P.* (2011). Aucubin modulates Bcl-2 family proteins expression and inhibits aspases cascade in H2O2-induced PC12 cells. Molecular Biology Reports, 38(5): 3561-3567. Xu Y.P., Li X.Y., Jin L.J.*, Zhen Y.H., Lu Y.N., Li S.Y., You J.S., Wang L.H. (2011). Application of chicken egg yolk immunoglobulins in the control of terrestrial and aquatic animal diseases: a review. Biotechnology Advances, 29(6): 860–868. Xu W.P., Reuter T., Xu Y.P., Hsu Y.H., Stanford K., McAllister T.A.* (2011). Field scale evaluation of bovine-specific DNA as an indicator of tissue degradation during cattle mortality composting. Bioresource Technology, 102(7): 4800-4806. Wang L.H., Li X.Y., Jin L.J., You J.S., Zhou Y., Li S.Y., Xu Y.P.* (2011). Characterization of chicken egg yolk immunoglobulins (IgYs) specific for the most prevalent capsular serotypes of mastitis-causingStaphylococcus aureus. Veterinary Microbiology, 149(3-4): 415-421. Wang T.T., Xu Y.P.*, Liu W.J., Sun Y.X., Jin L.J. (2011). Expression of Apostichopus japonicus lysozyme in the methylotrophic yeast Pichia pastoris. Protein Expression and Purification. 77(1): 20-25. Sha L., Xu Y.P.*, Jin L.J. (2011). A review of mink farming practices in China. Scientifur, 35(3):27-36. Xu W.P., Xu Y.P., Reuter T., Gilroyed B., Jin L.J., Stanford K.*, Larney F.J., McAllister T.A. (2010) An improved design for biocontained composting of cattle mortalities. Compost Science & Utilization. 18:32-41.

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