韩璐璐 - 大连理工大学 - 生物工程学院

个人简介

2023/1-今，大连理工大学，生物工程学院，教授 2019/12-今，大连理工大学，生物工程学院，博士生导师 2017/12-2022/12，大连理工大学，生物工程学院，副教授 2014/08-2017/11，大连理工大学，生命科学与技术学院，讲师 2012/08-2014/07，大连理工大学，生命科学与技术学院，师资博士后 2011/09-2011/12，西班牙CICbiomaGUNE生物材料研究中心，访问学者 2006/09-2012/03，浙江大学，材料科学与工程专业，博士学位（保研） 2002/09-2006/07，湖南大学，材料科学与工程专业，学士学位

研究领域

1）构筑与肿瘤细胞结构、生化特征精确匹配的材料表界面，提高血液中循环肿瘤细胞捕获效率和广谱性，用于癌症的早期检测；2）研制与循环肿瘤细胞生长自适应的水凝胶材料，提高循环肿瘤细胞类器官培养效率，用于癌症的个体化药物筛选；3）结合材料学与合成生物学，开发微生物复合的可编程活体材料，应用于生物传感、疾病治疗等领域。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Chong Zhang, Fen Zeng, Zhengyang Fan, Zhen He, Liang Tai, Qiang Peng, Yixin Zhang, Zhenhua Chao, Wenning Jiang, Lingyun Jia*, Lulu Han*. An Oral Polyphenol Host-Guest Nanoparticle for Targeted Therapy of Inflammatory Bowel Disease. Acta Biomaterialia, 2023. https://doi.org/10.1016/j.actbio.2023.08.020 Chong Zhang, Xiaorong Gao, Xinxiu Ren, Ting Xu, Qiang Peng, Yixin Zhang, Zhenhua Chao, Wenning Jiang, Lingyun Jia*, Lulu Han*. Bacteria-Induced Colloidal Encapsulation for Probiotic Oral Delivery. ACS Nano, 2023, 17 (7), 6886–6898. （纳米领域TOP期刊，中科院一区，影响因子18.027） Wenning Jiang, Lulu Han*, Guorui Li, Ying Yang, Qidong Shen, Bo Fan, Yuchao Wang, Xiaomin Yu, Yan Sun, Shengxiu He, Huakun Du, Jian Miao, Yuefeng Wang, and Lingyun Jia*. Bait-trap chip for accurate and ultrasensitive capture of living circulating tumor cells. Acta Biomaterialia, 2023, 162, 226-239. Lulu Han, Jiaxin Ji, Chong Zhang, Bingjian Sun, Zhenhua Chao, Hua Zhu, Xiaorong Gao Jun Ren, Fangling Ji, Liming Ma, Lingyun Jia*. One-Step Assembly of Versatile Multifunctional Coatings Based on Host-Guest and Polyphenol Chemistry. Small, 2023, e2206943, DOI: 10.1002/smll.202206943. （中科院一区，影响因子15.153, 入选Inside back cover） Ting Xu, Lulu Han*, Lingyun Jia*. Facile calcium ion-regulated grafting of dense and highly stretched hyaluronan for selective mediation of cancer cells rolling under high-speed flow. Acta Biomaterialia, 2022, 146, 177-186. Wenning Jiang, Lulu Han*, Liwei Yang, Ting Xu, Jiabei He, Ruilian Peng, Ziyu Liu, Chong Zhang, Xiaomin Yu, Lingyun Jia*. Natural fish trap-like nanocage for label-free capture of circulating tumor cells. Advanced Science, 2020, 7, 2002259. Lingyu Li, Lulu Han*, Jian Xie, Shuxin Liu, Lingyun Jia*. Multi-sites polycyclodextrin adsorbents for removal of protein-bound uremic toxins combining with hemodialysis. Carbohydrate Polymers, 2020, 247, 116665. Lulu Han, Ruilian Peng, Wenning Jiang, Ting Xu, Chong Zhang, Kaidi Chen, Yixin Zhang, Haiyuan Song, Lingyun Jia*. Coordination-driven reversible surfaces with site-specifically immobilized nanobody for dynamic cancer cell capture and release. Journal of Materials Chemistry B, 2020, 8 (33), 7511-7520. Liwei Yang, He Sun, Wenning Jiang, Ting Xu, Bing Song, Ruilian Peng, Lulu Han*, Lingyun Jia. A chemical method for specific capture of circulating tumor cells using label-free polyphenol-functionalized films. Chemistry of Materials, 2018, 30, 4372-4382. Liwei Yang, Lulu Han*, QiLiu, Yige Xu, Lingyun Jia*. Galloyl groups-regulated fibrinogen conformation: Understanding antiplatelet adhesion on tannic acid coating. Acta Biomaterialia, 2017, 64, 187-199. Liwei Yang, Lulu Han*, Lingyun Jia*. A Novel Platelet-Repellent Polyphenolic Surface and Its Micropattern for Platelet Adhesion Detection. ACS Applied Materials & Interfaces. 2016, 8 (40): 26570-26577. Lulu Han, Zhengwei Mao*, Jindan Wu, Yang Guo, Tanchen Ren, Changyou Gao*. Directional Cell Migration through Cell-Cell Interaction on Polyelectrolyte Multilayers with Swelling Gradients. Biomaterials. 2013, 34 (4): 975-984.