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个人简介

教育经历 2001.9 2006.3 大连理工大学 生物化工 博士 1988.9 1991.4 大连轻工学院 发酵工程 硕士 1982.9 1986.7 大连轻工学院 食品工程 学士 1980.9 1982.1 辽宁省岫岩高级中学 工作经历 1999.12 至今 大连理工大学 教师 1986.8 1999.12 大连轻工学院 教师 其他奖励 2015年度教学质量优良奖 (2016年) 2009年度教学质量优良将 (2010年) 2008年度教学质量优良奖 (2009年) 三育人先进个人 (2009年) 2007年度教学质量优良奖 (2008年) 环境与生命学院我最喜爱的教师 (2008年)

研究领域

蛋白质及酶工程;生物催化与转化;药物化学及药理;功能食品学。

近期论文

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李莹雪.芹菜素与丹参酮ⅡA 的协同抗肿瘤作用及机制[J],中草药,2021 郑世浩.玉米秸秆固态复合微生物菌肥发酵及应用[J],河南农业大学学报,2021 贾凌慧.石油降解低温细菌的筛选及降解特性的表征[J],环境工程,2021 Sheng Hao,Lu Yu-Feng,Bao Yong-Ming.基于TAP分子亲和力模型预测MHCⅠ类分子提呈短肽的免疫原性[J],生物化学与生物物理进展,2020,47(2):157-168 Guo, Jianli,Wang, Qingling,Zhang, Yue,Sun, Wenhui,Zhang, Shuangzhe,Li, Yachen,Wang, Jingyun,Bao, Yongming.Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer[J],PHARMACOLOGICAL RESEARCH,2019,147:104387 包永明,王庆玲,吴宪.温度响应的细菌生理生化特性调控研究进展[J],微生物学杂志,2018,38(6):1-14 Wang, Yuepeng,Sun, Wenhui,Zheng, Shihao,Zhang, Yue,Bao, Yongming.Genetic engineering of Bacillus sp. and fermentation process optimizing for diacetyl production[J],JOURNAL OF BIOTECHNOLOGY,2019,301:2-10 Guo, Jianli,Tang, Qin,Wang, Qingling,Sun, Wenhui,Pu, Zhongji,Wang, Jingyun,Bao, Yongming.Pifithrin-alpha enhancing anticancer effect of topotecan on p53-expressing cancer cells[J],EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES,2019,128:61-72 Pu, Zhongji,Zhao, Mengdi,Zhang, Yue,Sun, Wenhui,Bao, Yongming.Dynamic Description of the Catalytic Cycle of Malate Enzyme: Stereoselective Recognition of Substrate, Chemical Reaction, and Ligand Release[J],JOURNAL OF PHYSICAL CHEMISTRY B,2018,122(51):12241-12250 Yang, Decai,Qiu, Jieshan,Tian, Dongxu,Xue, Chuang,Gao, Fei,Liu, Yang,Li, Hong,Bao, Yongming,Liang, Jingjing,Zhao, Zongbin.Tuned Fabrication of the Aligned and Opened CNT Membrane with Exceptionally High Permeability and Selectivity for Bioalcohol Recovery[J],NANO LETTERS,2018,18(10):6150-6156 孜力汗,贾凌云,杨君,修志龙,包永明,袁文杰,牟英,唐颖.通过科研与教学的结合建设生物工程专业校内实习实训基地[J],化工高等教育,2018,35(3):75-81 Zhang Yue,Ji Fangling,Wang Jingyun,Pu Zhongji,Jiang Bo,Bao Yongming.Purification and characterization of a novel organic solvent-tolerant and cold-adapted lipase from Psychrobacter sp. ZY124.[J],Extremophiles : life under extreme conditions,2018,22(2):287-300 Chen, Lili,Qian, Ming,Zhang, Liuwei,Xia, Jing,Bao, Yongming,Wang, Jingyun,Guo, Lianying,Li, Yachen.Co-delivery of doxorubicin and shRNA of Beclin1 by folate receptor targeted pullulan-based multifunctional nanomicelles for combinational cancer therapy[J],RSC ADVANCES,2018,8(32):17710-17722 Ji, Fangling,Feng, Yanbin,Li, Mingyang,Yang, Yongliang,Wang, Tianqi,Wang, Jingyun,Bao, Yongming,Xue, Song.Studies on structure-function relationships of acetolactate decarboxylase from Enterobacter cloacae[J],RSC ADVANCES,2018,8(68):39066-39073 孙丽慧,王云晓,吕诗文,李曼,贺雷雨,包永明.1株高产L-乳酸菌株的分离鉴定及其发酵培养基优化[J],食品科学,2018,39(6):135-140 Ji, Fangling,Bao, Yongming,Li, Mingyang,Feng, Yanbin,Wu, Sijin,Wang, Tianqi,Pu, Zhongji,Wang, Jingyun,Yang, Yongliang,Xue, Song.Structural and enzymatic characterization of acetolactate decarboxylase from Bacillus subtilis.[J],Applied microbiology and biotechnology,2018,102(15):6479-6491 于海宁,徐品三,包永明.Transcriptome analysis of tomato leaf spot pathogen Fusarium proliferatum: De novo assembly, expression pro?ling and identi?cation of candidate effectors[J],International Journal of Molecular Sciences,2018,19(1) Wang, Qingling,Ji, Fangling,Guo, Jianli,Wang, Yuepeng,Li, Yanyan,Wang, Jingyun,An, Lijia,Bao, Yongming.LotS/LotR/Clp, a novel signal pathway responding to temperature, modulating protease expression via c-di-GMP mediated manner in Stenotrophomonas maltophilia FF11[J],MICROBIOLOGICAL RESEARCH,2018,214:60-73 Gao Meiling,Yao Siyu,Liu Yang,Yu Haining,Xu Pinsan,Sun Wenhui,Pu Zhongji,Hou Hongman,Bao Yongming.Transcriptome Analysis of Tomato Leaf Spot Pathogen Fusarium proliferatum: De novo Assembly, Expression Profiling, and Identification of Candidate Effectors.[J],International journal of molecular sciences,2017,19(1) 高美玲,刘阳,于海宁,侯红漫,包永明.层出镰孢菌原生质体制备条件的研究[J],安徽农业科学,2017,45(35):149-151,163 Tang, Qin,Ji, Fangling,Wang, Jingyun,Guo, Lianying,Li, Yachen,Bao, Yongming.Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin[J],EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES,2017,109:223-232 Pu, Zhongji,Ji, Fangling,Wang, Jingyun,Zhang, Yue,Sun, Wenhui,Bao, Yongming.Rational design of Meso-2,3-butanediol dehydrogenase by molecular dynamics simulation and experimental evaluations[J],FEBS LETTERS,2017,591(20):3402-3413 Lv, Shi-Wen,Sun, Li-Hui,Zhao, Shu-Yan,Bao, Yong-Ming.Effect of dry heat stabilisation on the functional properties of rice bran proteins[J],INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY,2017,52(8):1836-1843

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