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个人简介

2017.6-至今,深圳大学化学与环境工程学院,副教授 2009.3-2017.5,清华大学深圳研究生院,讲师,副教授 2007.3-2009.3,清华大学,博士后 2001.9-2006.12中国科学院广州化学研究所,博士 1997.9-2001.7徐州师范大学,学士

研究领域

研究方向:有机小分子或聚合物的设计、合成及应用 1.热电材料领域 探索和开发新型可再生清洁能源和高效能量转换与存储技术,具有重要的理论意义和市场应用前景。将热电材料用于工业废热回收、汽车尾气余热回收来进行发电,或用于制备空调系统,不仅可提高燃油的利用率,还可降低废气的排放,保护环境。本课题组致力于小分子或高分子聚合物热电材料的研究,探讨化合物结构对热电性能的影响,研发性能优异的热电材料。 2.肿瘤治疗领域 肿瘤疾病严重威胁人类的生命健康,本课题组针对肿瘤的信号传导网络,设计研发新的药物先导化合物,研究其抗肿瘤活性及其作用机制。

1.吖啶/碳纳米管复合热电材料的制备及性能研究深圳市基础研究计划 2019-2020,50万元 2.基于系统药理学和高通量筛选技术的多靶点抗肿瘤药物研发,863子课题,2012-2015,2012AA020305,92.5万元 3.基于靶点拓扑异构酶和PARP1的吖啶类化合物的合成与抗肿瘤活性研究,国家自然科学基金面上项目,2014-2017,80万元 4.端粒酶抑制剂:特异性识别肿瘤细胞的吖啶酮类化合物的合成及活性研究,国家自然科学基金青年基金,2010-2012,20902053,19万元 5.新型磷酰化苯并内酰胺药物的合成和生物活性研究,中国博士后科学基金,2007-2009,3万元 6.普20150266:新靶点及多靶点组合抗肿瘤药物技术研发,深圳市技术开发,2015-2017,200万元 7.以DNA甲基转移酶与组蛋白去乙酰化酶为靶点的化合物的设计、合成与活性研究,深圳市基础研究计划,2015-2017, 30万元

近期论文

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1.Shichao Wang, Fuwei Liu, Chunmei Gao*, Tao Wan, Luhai Wang, Li Wang, Lei Wang* Enhancement of the thermoelectric property of nanostructured polyaniline/carbon nanotube composites by introducing pyrrole unit onto polyaniline backbone via a sustainable method,Chemical Engineering Journal, 2019, accept. IF: 6.735(JCR1) 2.Tao Wan, Xiaojun Yin, Chenjun Pan, Danqing Liu, Xiaoyan Zhou, Chunmei Gao*, Wai-Yeung Wong*, Lei Wang *, Boosting the adhesivity of π-conjugated polymers by embedding platinum acetylides towards high-performance thermoelectric composites, Polymers, 2019, accept. IF: 2.935(JCR2) 3.Yan Zhou, Yijia Liu, Xiaoyan Zhou, Yuan Gao, Chunmei Gao*, and Lei Wang*, High performance p-type organic thermoelectric materials based on metalloporphyrin/single-walled carbon nanotube composite films, Journal of Power Sources, 2019, 423, 152-158. IF: 6.945(JCR1) 4.Xiaoyan Zhou, Chengjun Pan, Ansheng, Liang, Luhai, Wang, Tao Wan, Guanghui Yang, Chunmei Gao* and Wai-Yeung Wong, Enhanced figure of merit of poly(9,9-di-n-octylfluorene-altbenzothiadiazole) and SWCNT thermoelectric composites by doping with FeCl3, Journal of Applied Polymer Science, 2019, 136, 47011. IF: 1.901 (JCR3) 5.Chunmei Gao, Yijia Liu, Yuan Gao*, Yan Zhou, Xiaoyan Zhou, Xiaojun Yin, Chengjun Pan, Chuluo Yang, Hanfu Wang, Guangming Chen*, and Lei Wang*, High-performance n-type thermoelectric composites of acridones with tethered tertiary amines and carbon nanotubes, Journal of Materials Chemistry A, 2018, 6, 20161–20169. IF: 9.931(JCR1)(2018 JMCA hot papers) 6.Xiaojun Yin, Yuhao Peng, Jiajia Luo, Xiaoyan Zhoum, Chunmei Gao*, Lei Wang*, Chuluo Yang*, Tailoring the framework of organic small molecule semiconductors towards high-performance thermoelectric composites via conglutinated carbon nanotube webs, Journal of Materials Chemistry A, 2018, 6, 8323-8330. IF: 9.931(JCR1) 7.Yufeng Xue, Chunmei Gao(共同一作), Lirong Liang, Xin Wang, Guangming Chen*. Nanostructure controlled construction of high-performance thermoelectric materials of poly(mers and their composites, Journal of Materials Chemistry A, 2018, 6, 22381-90. IF: 9.931(JCR1) 8.Luhai Wang, Chengjun Pan*, Zhongming Chen, Xiaoyan Zhou, Chunmei Gao* and Lei Wang*, A study of the thermoelectric properties of benzo[1,2-b:4,5-b′]dithiophene–based donoracceptor conjugated polymers, Polymer Chemistry, 2018, 9, 4440-4447. IF: 4.927 (JCR1) 9.Bin Zhang, Ning Wang, Cunlong Zhang, Chunmei Gao*, Wei Zhang, Kang Chen, Yuyang Jiang*,Novel multi-substituted benzyl acridone derivatives as survivin inhibitors for hepatocellular carcinoma treatment, European Journal of Medicinal Chemistry, 2017, 129, 337-348. IF: 4.816 (JCR2) 10.Dan Li, Zigao Yuan, Shaopeng Chen, Cunlong Zhang, Lu Song, Chunmei Gao*, Yuzong Chen, Chunyan Tan, and Yuyang Jiang*, Synthesis and biological research of novel azaacridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors, Bioorganic & Medicinal Chemistry, 2017, 25, 3437-3446. IF: 2.881 (JCR3) 11.Zigao Yuan, Qinsheng Sun, Dan Li, Shuangshuang Miao, Shaopeng Chen, Lu Song, Chunmei Gao*, Yuzong Chen, Chunyan Tan, Yuyang Jiang*, Design, synthesis and anticancer potential of NSC-319745 hydroxamic acid derivatives as DNMT and HDAC inhibitors, European Journal of Medicinal Chemistry, 2017,134, 281-92. IF: 4.816 (JCR2) 12.Zigao Yuan, Shaopeng Chen, Qinsheng Sun, Ning Wang, Dan Li, Shuangshuang Miao, Chunmei Gao*, Yuzong Chen, Chunyan Tan, Yuyang Jiang*, Olaparib hydroxamic acid derivatives as dual PARP and HDAC inhibitors for cancer therapy, Bioorganic & Medicinal Chemistry, 2017, 25, 4100-4109. IF: 2.881 (JCR3) 13.Zigao Yuan, Jiwei Chen, Wenlu Li, Dan Li, Changjun Chen, Chunmei Gao*, Yuyang Jiang*, PARP inhibitors as antitumor agents: a patent update (2013-2015), Expert Opinion on Therapeutic Patents, 2017, 27, 363-382. IF: 4.598(JCR2) 14.Zigao Yuan, Shaopeng Chen, Changjun Chen, Jiwei Chen, Chengken Chen, Qiuzi Dai, Chunmei Gao*, and Yuyang Jiang*, Design, synthesis and biological evaluation of 4-amidobenzimidazole acridine derivatives as dual PARP and Topo inhibitors for cancer therapy European Journal of Medicinal Chemistry, 2017,138, 1135-1146. IF: 4.816 (JCR2) 15.Zhishan Cui, Shaopeng Chen, Yanwei Wang, Chunmei Gao*, Yuzong Chen, Chunyan Tan, Yuyang Jiang*, Design, synthesis and evaluation of azaacridine derivatives as dual-target EGFR and Src kinase inhibitors for antitumor treatment. European Journal of Medicinal Chemistry, 2017, 136, 372-381. IF: 4.816 (JCR2) 16.Wei Zhang, Bin Zhang, Wei Zhang, Ti Yang, Ning Wang, Chunmei Gao*, Chunyan Tan, Hongxia Liu, Yuyang Jiang*. Synthesis and antiproliferative activity of 9-benzylamino-6-chloro-2-methoxy-acridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors. European Journal of Medicinal Chemistry, 2016,116, 59-70. IF: 4.816 (JCR2) 17.Huixiong Xie, Dan Tao, Jiangpeng Ni, Xiongzhi Xiang, Chunmei Gao*, Lei Wang*. Synthesis and properties of highly branched star-shaped sulfonated block polymers with sulfoalkyl pendant groups for use as proton exchange membranes. Journal of Membrane Science,2016, 497, 55-66. IF: 6.578 (JCR1) 18.Wenlu Li, Xi Li, Bin Zhang, Chunmei Gao*, Yuzong Chen, Yuyang Jiang*. Current progresses and trends in the development of progesterone receptor modulators. Current Medicinal Chemistry, 2016,23, 2507-2554. IF: 3.469 (JCR2) 19.Zhishan Cui, Xi Li, Lulu Li, Bin Zhang*, Chunmei Gao*, Yuzong Chen, Chunyan Tan, Hongxia Liu, Weiyi Xie, Ti Yang, & Yuyang Jiang. Design, synthesis and evaluation of acridine derivatives as multi-target Src and MEK kinase inhibitors for anti-tumor treatment. Bioorganic & Medicinal Chemistry, 2016,24, 261-269. IF: 2.881 (JCR3) 20.Changjun Chen, HaiyangLiu, Bin Zhang, Yanwei Wang, Kai Cai, Ying Tan*, Chunmei Gao*, Hongxia Liu, Chunyan Tan, Yuyang Jiang. A simple benzimidazole quinoline-conjugate fluorescent chemosensor for highly selective detection of Ag+. Tetrahedron, 2016,72, 3980-3985. IF: 2.377 (JCR3) 21.Chunmei Gao*, Wei Zhang, Shengnan He, Shangfu Li, Feng Liu*, Yuyang Jiang, Synthesis and antiproliferative activity of 2,7-diamino l0-(3,5-dimethoxy)benzyl-9(10H)-acridone derivatives as potent telomeric G-quadruplex DNA ligands, Bioorganic Chemistry, 2015, 60, 30-36. IF: 3.929 (JCR3) 22.Bin Zhang, Kang Chen, Ning Wang, Chunmei Gao*, Qinsheng Sun, Lulu Li, Yuzong Chen, Chunyan Tan, Hongxia Liu, Yuyang Jiang*, Molecular design, synthesis and biological research of novel pyridyl acridones as potent DNA-binding and apoptosis-inducing agents. European journal of medicinal chemistry, 2015, 93, 214-26. IF: 4.816 (JCR2) 23.Xi Li, Chunmei Gao*, Ti Yang, Bin Zhang, Chunyan Tan, Hongxia Liu, Yuyang Jiang*, A POCl3-mediated synthesis of substituted fused azoacridones derivatives. Rsc Advances, 2015, 5, 28670-8. IF: 2.936 (JCR3) 24.Chunmei Gao*, Bin Li, Bin Zhang, Qinsheng Sun, Lulu Li, Xi Li, Changjun Chen, Hongxia Liu, Yuyang Jiang*, Synthesis and biological evaluation of benzimidazole acridine derivatives as potential DNA-binding and apoptosis-inducing agents. Bioorganic & Medicinal Chemistry, 2015, 23, 1800-1807. IF: 2.881 (JCR3) 25.Hongbo Chen, Xiaobin Zeng, Chunmei Gao(并列一作), Pinghong Ming, Jianping Zhang, Caiping Guo, Lanzhen Zhou, Yin Lu, Lijun Wang, Laiqiang Huang*, Xiangjiu He*, Lin Mei*, A new arylbenzofuran derivative functions as an anti-tumour agent by inducing DNA damage and inhibiting PARP activity. Scientific Reports, 2015, 5, 10893. IF: 4.122 (JCR3) 26.Bin Zhang, Xi Li, Bin Li, Chunmei Gao*, Yuyang Jiang*,Acridine and its derivatives: a patent review (2009-2013). Expert opinion on therapeutic patents, 2014, 24, 647-664. IF: 4.598(JCR2) 27.Bin Li, Chunmei Gao*, Qinsheng Sun, Lulu Li, Chunyan Tan, Hongxia Liu, Yuyang Jiang*, Novel synthetic acridine-based derivatives as topoisomerase I inhibitors. Chinese Chemical Letters, 2014, 25, 1021-1024. IF: 2.631(JCR4) 28.Xuliang Lang, Qinsheng Sun, Yuzong Chen, Lulu Li, Chunyan Tan, Hongxia Liu, Chunmei Gao*, Yuyang Jiang*, Novel synthetic 9-benzyloxyacridine analogue as both tyrosine kinase and topoisomerase I inhibitor. Chinese Chemical Letters,2013, 24, 677-680. IF: 2.631(JCR4) 29.Xuliang Lang, Lulu Li, Yuzong Chen, Qinsheng Sun, Qin Wu, Feng Liu, Chunyan Tan, Hongxia Liu, Chunmei Gao*, Yuyang Jiang*, Novel synthetic acridine derivatives as potent DNA-binding and apoptosis-inducing antitumor agents. Bioorganic & Medicinal Chemistry, 2013, 21:4170-7 IF: 2.881 (JCR3) 30.Jinshun Lin, Xiuli Jin, Yiwen Bu, Deliang Cao, Nannan Zhang, Shangfu Li, Qinsheng Sun, Chunyan Tan, Chunmei Gao*, Yuyang Jiang*, Efficient synthesis of RITA and its analogues: derivation of analogues with improved antiproliferative activity via modulation of p53/miR-34a pathway. Organic & Biomolecular Chemistry, 2012, 10, 9734-46. IF: 3.423 (JCR2) 31.Chunmei Gao*, Shangfu. Li, Xuliang Lang, Hongxia Liu, Feng Liu, Chunyan Tan, & Yuyang Jiang*, Synthesis and evaluation of 10-(3,5-dimethoxy)benzyl-9(10H)-acridone derivatives as selective telomeric G-quadruplex DNA ligands, Tetrahedron, 2012, 68, 7920-7925. IF: 2.377 (JCR3) 32.Xuliang Lang, Xudong Luan, Chunmei Gao*, Yuyang Jiang*, Recent Progress of Acridine Derivatives with Antitumor Activity, Progress in Chemistry, 2012, 24, 1497-505. IF: 0.82 (JCR4) 33.Lei Wang, Guangming Zhu, Junqin Li, Chunmei Gao*, Synthesis and characterization of partially fluorinated poly(fluorenyl ether ketone)s with different degrees of sulfonation as proton exchange membranes, Polymer Bulletin,2011, 66 (7), 925-937. IF: 1.589 (JCR4) 34.Chunmei Gao, Feng Liu, Xudong Luan, Chunyan Tan, Hongxia Liu, Yonghua Xie, Yibao Jin, Yuyang Jiang*, Novel synthetic 2-amino-10-(3,5-dimethoxy)benzyl-9(10H)-acridinone derivatives as potent DNA-binding antiproliferative agents, Bioorganic & Medicinal Chemistry, 2010, 18, 7507-7514. IF: 2.881 (JCR3) 35.Chunmei Gao, Yuyang Jiang*, Chunyan Tan, Xuyu Zu, Huacheng Liu, Derong Cao, Synthesis and potent antileukemic activities of 10-benzyl-9(10H)-acridinones. Bioorganic & Medicinal Chemistry, 2008, 16, 8670-8675. IF: 2.881 (JCR3) 36.Chunmei Gao, Huacheng Liu, Yuyang Jiang*, Chunyan Tan, Derong Cao, Synthesis of 10-Benzyl-9-acridone and Its Reduction with NaBH4, Chinese Journal of Organic Chemistry, 2008, 28,1803-1806. IF: 1.392 (JCR4) 37.Chunmei Gao, Derong Cao*, Sheyang Xu, Herbert Meier, Acid-catalyzed cyclization of anthracenol derivatives to homotriptycenes, Journal of Organic Chemistry, 2006, 71, 3071-3076. IF: 4.805 (JCR2) 38.Chunmei Gao, Derong Cao, Sheyang Xu. Acid-catalyzed selective cyclization of 10,10-dibenzyl-9(10H)-anthranol, Acta Chim Sinica, 2006, 64, 1757-60. IF: 2.735 (JCR4)

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