个人简介
杨成彬,助理教授,硕士生导师,深圳市海外高层次人次(孔雀计划C类),新加坡南洋理工大学工学博士学位。主要从事于肿瘤基因治疗技术的开发和应用工作。迄今为止,共发表SCI论文40余篇,文章总被引680余次。相关研究成果发表在Nano Energy, ACS applied materials & interfacesl, Advanced Healthcare Materials, Nano Research, Nanoscale,以及Theranostics等国际知名期刊上。作为主持人承担国家自然科学基金青年基金1项, 省市级项目3项,校级启动项目1项。
研究领域
1.肿瘤基因治疗
2.基因/药物靶向递送
3.基因电转染系统开发
近期论文
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Chengbin Yang, Kok Ken Chan, Gaixia Xu*, Mingjie Yin, Guimiao Lin, Xiaomei Wang, Wei-Jen Lin, Muhammad Danang Birowosuto, Shuwen Zeng, Takashi Ogi, Kikuo Okuyama, Fitri Aulia Permatasari, Ferry Iskandar, Chih-Kuang Chen*, Ken-Tye Yong*. Biodegradable polymer coated multifunctional graphene quantum dots for light-triggered synergetic therapy of pancreatic cancer. ACS applied materials & interfaces. 2019, 11 (3), 2768-2781. (IF:8.456,中科院一区,Top期刊)
Chengbin Yang, Guang Yang, Qingling Ouyang, Shuangyang Kuang, Peiyi Song, Gaixia Xu, Daniel Puiu Poenar, Guang Zhu*, Ken-Tye Yong*, Zhong Lin Wang*. Nanowire-array-based gene electro-transfection system driven by human-motion operated triboelectric nanogenerator. Nano Energy. 2019, 64, 103901. (IF:15.548,中科院一区,Top期刊)
Chengbin Yang, Mingjie Yin, Gaixia Xu, Wei‐Jen Lin, Jiajie Chen, Yinling Zhang, Tao Feng, Peng Huang*, Chih‐Kuang Chen*, Ken‐Tye Yong*. Biodegradable polymers as a noncoding miRNA nanocarrier for multiple targeting therapy of human hepatocellular carcinoma. Advanced Healthcare Materials. 2019, 8(8), 1801318. (IF:6.27,中科院一区,Top期刊)
Chengbin Yang, Kok Ken Chan, Wen-Jen Lin, Alana Mauluidy Soehartono, Guimiao Lin, Huiting Toh, Ho Sup Yoon, Chih-Kuang Chen*, Ken-Tye Yong*. Biodegradable nanocarrier for siRNA co-delivery strategy increasing the chemosensitivity of pancreatic cancer cells to Gemcitabine. Nano Research, 2017, 10(9), 3049–3067. (IF:8.515,中科院一区,Top期刊)
Chengbin Yang#, Nishtha Panwar#, Yucheng Wang, Butian Zhang, Maixian Liu, Huiting Toh, Ho Sup Yoon, Swee Chuan Tjin, Peter Han Joo Chong, Wing-Cheung Law, Chih-Kuang Chen*, Ken-Tye Yong*. Biodegradable charged polyester-based vectors (BCPVs) as an efficient non-viral transfection nanoagent for gene knockdown of the BCR–ABL hybrid oncogene in a human chronic myeloid leukemia cell line. Nanoscale, 2016, 17(8), 9405-9416. (IF:6.97,中科院一区,Top期刊)