个人简介
文殊
职务: 教授
专业: 微生物学
Education/Working Experience
9/2005-10/2008, Dalian Medical University, Biochemistry and Molecular Biology,Doctor
9/1999-10/2002, Dalian University of Technology, Biochemical Engineering Bachelor
9/1987-7/1991, East China University of Science and Technology, Biochemical Engineering, Master
7/1991 - now Dalian Medical University College of Basic Medical Sciences Department of microecology teacher
Research Projects/Grants
1.Principal Investigator of National Natural Science Fund Project of China 81150014. Effect and Mechanism of gastrointestinal and respiratory microbiota colonization on immune tolerance and asthma development. 2012
2.Principal Investigator of National Natural Science Fund Project of China 81370113 Effect and Mechanism of Microbiota Colonization on the Immune Tolerance and Atopic March 2014.1-2017.12
3.The National High Technology Research and Development Program("863"Program) of China SS2014AA022209. Establishment and application of culture collection for clinical nutrition 2014.1-2016.12
Admission Plan/Requirements
Microbiology: 1 student
近期论文
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1. Wenkai Yu; Xiaopeng Yuan; Xingche Xu; Rui Ding; Liyuan Pang; Yinhui Liu ; Yanjie Guo ; Huajun Li ; Ming Li ; Jieli Yuan ;Li Tang; and Shu Wen.Reduced airway microbiota diversity is associated with elevated allergic respiratory inflammation 2015,115(1): 63-68
2.Ming Li , Pin Liang , Zhenzhen Li , Ying Wang , Guobin Zhang , Hongwei Gao ,
Shu Wen , and Li Tang. Fecal microbiota transplantation and bacterial consortium transplantation have comparable effects on the re-establishment of mucosal barrier function in mice with intestinal dysbiosis. Frontiers in Microbiology,2016(6)692.
3.Ming Li, Weihua Li, Shu Wen（coauthor）, Yinhui Liu and Li Tang. Effects of ceftriaxone-induced intestinal dysbacteriosis on dendritic cells of small intestine in mice. Micorobiology and immunology. 2013, 57(8):561-8.
4.Fei Gao, Ming Li, Yinhui Li, Chuanzhou Gao, Shu Wen1 and Li Tang.( coauthor ) Intestinal dysbacteriosis induces changes of T lymphocyte subpopulations in Peyer's patches of mice and orients the immune response towards humoral immunity. Gut Patho, 2012.4（1）：19.
5. Shu Wen , Hong Li , Mo-Li Wu, Shao-Hua Fan, Qian Wang , Xiao-Hong Shu , Qing-You Kong, Xiao-Yan Chen, Jia Liu. Inhibition of NF-kB signaling commits resveratrol-treated medulloblastoma cells to apoptosis without neuronal differentiation. J Neurooncol.104(1):169–177,2011.
6. Fei Gao, Ming Li, Yinhui Liu, Chuanzhou Gao, Shu Wen*, Li Tang*. Intestinal dysbacteriosis induces changes of T lymphocyte subpopulations in Peyer's patches of mice and orients the immune response towards humoral immunity. Gut Patho, 2012, 4:19.
7. Zongxin Ling, Shu Wen and Li Tang. Inhibition of VSV by Extracellular RNA from Culture Filtrate of Lactobacillus DM8909 in Vitro. Journal of Hard Tissue Biology. 20(3): 237-246,2011.
8. Chun-Liang Liu, Shu Wen, Yin-Hui Liu, Hua-Jun Li, Jing Xiao, Li Tang. Extracellular Nucleic Acids Secreted by Lactobacillus Regulate TLR9 Expression. Journal of Hard Tissue Biology. 20(2): 153-160, 2011.
9. Lisha Tan, Shu Wen, Ming-ZhongSun, Li Tang. Changes in Protein Profile in Cecum of Mouse with Intestinal Dysbacteriosis Induced by Ceftriaxone Sodium. Journal of Hard Tissue Biology. 20(2): 93-98, 2011.
10. Shu Wen, Hong Li, Jia Liu. Epigenetic Background of Neuronal Fate Determination Progress in Neurobiology. 87(2): 98-117,2009.
11. Shu Wen, Hong Li, Jia Liu. Dynamic Signaling for Neural Stem Cell Fate Determination. Cell Adhesion & Migration. 3(1): 107-117,2009.
12. Liu ZL, Li Y, Kong QY, Zhan C, Wang Q, Chen XY, Sun Y, Wen S, Tu CX, Liu J, Li H. Immunohistochemical Profiling of Wnt, NF-κB, Stat3 and Notch Signaling in Human Epidermal Tumors. J Dermatol Sci. 52(2):133-136,2008.
学术兼职
deputy director of the youth committee in microecology branch of Chinese Preventive Medical Association
Candidate director of the committee in immunology and microbiology section of Dalian Medical Association
Editorial in Chinese Journal of Microecology.
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