个人简介
李炜玲，博士，教授，硕士生导师。现任职于大连医科大学生物技术系。2007年毕业于大连医科大学，获生物化学与分子生物学硕士学位。2007年由国家留学基金委资助赴英国肿瘤研究中心学习，2011年英国爱丁堡大学肿瘤医学专业博士毕业。同年大连医科大学海外归国留学人才引进至生物技术系。2016年赴美国哈佛大学肿瘤研究中心进修。到目前为止，在Oncogene, Pigment Cell & Melanoma Research等国际顶尖学术期刊发表学术论文。
近期论文
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1. Jia Liu; Guoqiang Jiang; Ping Mao; Jing Zhang; Lin Zhang; Likun Liu; Jia Wang; Lawrence Owusu;Baoyin Ren;Yawei Tang;Weiling Li*. Down-regulation of GADD45A enhances chemosensitivity in melanoma. scientific report.2018,8: 4111-4122.
2. Liu, Jia; Zhang, Lin; Mao, Ping; Jiang, Guoqiang; Liu, Likun; Wang, Jing; Yang, Wei; Owusu, Lawrence;Li,Weiling*. Functional characterization of a novel transcript of ERCC1 in chemotherapy resistance of ovarian cancer. ONCOTARGET. 2017. 8(49): 85759-85771
3. Zhang, Lin; Ren, Baoyin; Zhang, Jing; Liu, Likun; Liu, Jia; Jiang, Guoqiang; Li, Man; Ding, Yuejia;Li,Weiling*. Anti-tumor effect of Scutellaria barbata D. Don extracts on ovarian cancer and its phytochemicals characterisation. JOURNAL OF ETHNOPHARMACOLOGY.2017,206: 184-192.
4. Jiang ,Guoqiang#; Liu,Jia#; Ren,Baoyin; Zhang,Lin; Owusu; Liu,Likun; Zhang,Jing; Tang,Y; Li,Weiling*. Anti-tumor and chemosensitization effects of Cryptotanshinone extracted from Salvia miltiorrhiza Bge. on ovarian cancer cells in vitro. Journal of Ethnopharmacology. 2017, 205: 33~40.
5.Jiang G, Liu J, Ren B, Tang Y, Owusu L, Li M, Zhang J, Liu L, Li W*. Anti-tumor effects of osthole on ovarian cancer cells in vitro.Journal of ethnopharmacology. 2016, 193:368-376.2.
6.Zhang L, Zhang J, Qi B, Jiang G, Liu J, Zhang P, Ma Y, Li W*. The anti-tumor effect and bioactive phytochemicals of Hedyotis diffusa willd on ovarian cancer cells. J Ethnopharmacol. 2016, 192:132-139.
7.Liu J, Bai J, Jiang G, Li X, Wang J, Wu D, Owusu L, Zhang E, Li W*. Anti-Tumor Effect of Pinus massoniana Bark Proanthocyanidins on Ovarian Cancer through Induction of Cell Apoptosis and Inhibition of Cell Migration. PLoS One. 2015;10(11):e0142157.
8.Owusu L, Wang B, Du Y, Li W*, Xin Y*. The quantum of initial transformed cells potentially modulates the type of local inflammation mechanism elicited by surrounding normal epithelial tissues and systemic immune pattern for tumor arrest or progression. Journal of Cancer. 2015;1;6(2):128-38.
9.Chen Y, Liu ZJ, Liu J, Liu LK, Zhang ES, Li WL*. Inhibition of metastasis and invasion of ovarian cancer cells by crude polysaccharides from rosa roxburghii tratt in vitro. Asian Pac J Cancer Prev. 2014;15(23):10351-4.
10. Li, Weiling, Li, Ye, Zhao, Yuwan, Yuan, Jieli, Mao, Weifeng. INHIBITION EFFECTS OF SCORPION VENOM EXTRACTS (BUTHUS MATENSII KARSCH) ON THE GROWTH OF HUMAN BREAST CANCER MCF-7 CELLS. AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES. 2014 ; 11 ( 5): 105 -110
11. Li, Weiling; Xin, Yi; Chen, Yang; Li, Xinli; Zhang, Cuili; Bai, Jing; Yuan, Jieli .The anti-proliferative effects and mechanisms of low molecular weight scorpion BmK venom peptides on human hepatoma and cervical carcinoma cells in vitro . ONCOLOGY LETTERS. 2014 ; 8 ( 4): 1581 - 1584
12. Li, W. *; Wu, D.; Wei, B.; Wang, S.; Sun, H. X.; Li, X. L.; Zhang, F.; Zhang, C. L.; Xin, Y. ANTI-TUMOR EFFECT OF CACTUS POLYSACCHARIDES ON LUNG SQUAMOUS CARCINOMA CELLS (SK-MES-1) .AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES , 2014, ; 11 ( 5): 99 - 104.
13. Li W, Melton DW*. 2012. Cisplatin regulates the MAPK kinase pathway to induce increased expression of DNA repair gene ERCC1 and increase melanoma chemoresistance. Oncogene. 10;31(19):2412-2422.
14. Li W, Song L, Ritchie AM, Melton DW*. 2012. Increased levels of DUSP6 phosphatase stimulate tumourigenesis in a molecularly distinct melanoma subtype. Pigment Cell Melanoma Res. 25(2):188-199.
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