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个人简介

刘帅,博士,副教授,硕士生导师。现任大连医科大学基础医学院生物化学与分子生物学教研室教师。荣获辽宁省第八批“百千万人才工程” 万层次、辽宁省优秀人才等荣誉称号。

研究领域

糖生殖生物学

近期论文

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1. Zheng Q, Li Y, Zhang D, Cui X, Dai K, Yang Y, Liu S*, Tan J*, Yan Q*. ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats. Cell Death Dis. 2017 Oct 26;8(10):e3145. (IF 5.9650) 2. Zheng Q, Zhang D, Yang YU, Cui X, Sun J, Liang C, Qin H, Yang X, Liu S*, Yan Q*. MicroRNA-200c impairs uterine receptivity formation by targeting FUT4 and α1,3-fucosylation. Cell Death Differ. 2017 Dec;24(12):2161-2172. (IF 8.3389) 3. Zheng Q, Cui X, Zhang D, Yang Y, Yan X, Liu M, Niang B, Aziz F, Liu S*, Yan Q*, Liu J*. miR-200b inhibits proliferation and metastasis of breast cancer by targeting fucosyltransferase IV and α1,3-fucosylated glycans. Oncogenesis. 2017 Jul 10;6(7):e358. (IF 4.143) 4. Liu C, Liang X, Wang J, Zheng Q, Zhao Y, Khan MN, Liu S*, Yan Q. Protein O-fucosyltransferase 1 promotes trophoblast cell proliferation through activation of MAPK and PI3K/Akt signaling pathways. Biomed Pharmacother. 2017 Apr;88:95-101. (IF 2.7590) 5. Zheng Q, Dai K, Cui X, Yu M, Yang X, Yan B, Liu S, Yan Q. Leukemia inhibitory factor promote trophoblast invasion via urokinase-type plasminogen activator receptor in preeclampsia. Biomed Pharmacother. 2016 May;80:102-8. (IF 2.7590) 6. Liu S, Zheng Q, Cui XY, Dai KX, Yang XS, Li FS, Yan Q. Expression of uPAR in human trophoblast and its role in trophoblast invasion. Int J Clin Exp Pathol. 2015 Nov 1;8(11):14325-34. (IF 1.5823) 7. Liu S, Wang J, Qin HM, Yan XM, Yang XS, Liu C, Yan Q. LIF upregulates poFUT1 expression and promotes trophoblast cell migration and invasion at the fetal-maternal interface. Cell Death Dis. 2014 Aug 28;5:e1396.(IF:5.177) 8. Liu S, Yang X, Wang J, Wei J, Zhang D, Wang X, Yan Q. Differential expression of LeY and fucosyltransferase IV correlates with the receptivity of RL95-2 and HEC-1A human uterine epithelial cells. Cell Biol Int. 2012 May 1;36(5):469-74. (IF:1.64) 9. Liu S, Yang X, Liu Y, Wang X, Yan Q. sLeX/L-selectin mediates adhesion in vitro implantation model. Mol Cell Biochem. 2011 Apr;350(1-2):185-92. (IF:2.33) 10. Gao J, Yan Q, Liu S, Yang X.Knockdown of EpCAM enhances the chemosensitivity of breast cancer cells to 5-fluorouracil by downregulating the antiapoptotic factor Bcl-2.PLoS One. 2014 Jul 14;9(7):e102590. (IF:3.534) 11. Gao J, Yan Q, Wang J, Liu S, Yang X.Epithelial-to-Mesenchymal Transition Induced by TGF-β1 Is Mediated by AP1-Dependent EpCAM Expression in MCF-7 Cells.J Cell Physiol. 2014 Sep 9. (IF:3.874) 12. Wang J, Liu S, Qin HM, Zhao Y, Wang XQ, Yan Q. Pregnancy-associated plasma protein A up-regulated by progesterone promotes adhesion and proliferation of trophoblastic cells. Int J Clin Exp Pathol. 2014 Mar 15;7(4):1427-37. (IF:1.783) 13. Yang X, Wang J, Liu S, Yan Q. HSF1 and Sp1 regulate FUT4 gene expression and cell proliferation in breast cancer cells. J Cell Biochem. 2014 Jan;115(1):168-78. (IF:3.368) 14. Yang X, Liu S, Yan Q.Role of fucosyltransferase IV in epithelial-mesenchymal transition in breast cancer cells. Cell Death Dis. 2013 Jul 25;4:e735. (IF:5.177)

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