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个人简介

樊建慧 职务: 副教授 专业: 生物化学与分子生物学 Education/Working Experience Education Experience 2009.9-2012.12 Dalian Medical University Major: Biochemistry and Molecular Biology Research: Function of glycans in tumor cells. Degree: Ph.D. 2003.9-2006.06 Dalian Medical University Major: Biochemistry and Molecular Biology Research: Function of ribonuclease inhibitor in tumor cells. Degree: Master 1998.9-2003.06 Chengde Medical University Major: Clinical Medicine Degree: Bachelor Working Experience 2006.7- Biochemistry and Molecular Biology Department of Dalian Medical University Research area:Tumor Biology Structure and functions of human ribonuclease inhibitor in tumor cells. The effects of glucosaminyltransferase on tumor cell metastasis Research Projects/Grants 1. The role of N-acetylglucosaminyltransferase IV in synthesis of N-glycan branches and in lymph node metastasis potential in mouse hepatocarcinoma cells. 2010.1-2012.12 (the third participant) National Natural Science Foundation of China (NSFC NO. 30970648) 2. The effects of GnT-Ⅴ expression and N-glycosylation of transporter on the chemosensitivity in bladder cancer. 2015.01-2017.12 (in charge) National Natural Science Foundation of China (NSFC NO. 31400687) Admission Plan/Requirements Admission Plan: Master degree student, 1-2 /Year Requirements: 1. The student should be non-Chinese citizens with a valid passport, should be between 20-35 years old, healthy, and has obtained bachelor degree with good marks. 2. He/her native language is English or the official language is English.

近期论文

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1. Tang Y, Liu P, Tian Y, Xu Y, Ren F, Cui X, Fan J*. Overexpression of ribonuclease inhibitor defines good prognosis and suppresses proliferation and metastasis in human colorectal cancer cells via PI3K/AKT pathway. Clin Transl Oncol. 2015, 17(4):306-313. (corresponding author) 2. Arshad Ahmed Padhiar, Jianhui Fan, Ying Tang, Juanhan Yu, Shujing Wang, Linhua Liu, Bachir Niang, Max Efui Annani-Akollor, Lifen Wang, Qi Wang, Jianing Zhang. Upregulated β1-6 branch N-glycan marks early gliomagenesis but exhibited biphasic expression in the progression of astrocytic glioma. Am J Cancer Res.2015, 5(3):1101-1116. 3. FAN Jian-hui, HE Jing-na, WANG Shu-jing, ZHENG Wei-long, JIN Li-yuan, ZHANG Jia-ning*. Construction and application of lentiviral-based system against N-Acetylglucosaminyltransferase. Chinese Journal of Microecology, 2014, 26(5): 518-521. 4. ZHANG Hai-feng,WANG Zhu-xin,ZHANG Jie,LI Wei,FAN Jian-hui*. The significance of VEGF expression in serum and cancer tissue in colon cancer patients. Chinese Journal of Microecology. 2014, 26(10): 1151-1154. (corresponding author) 5. Jianhui Fan, Ying Tang, Jingna He, Shujing Wang, Lifen Wang, Jianing Zhang*;Silencing of GnT-V Potentiates the Antitumor Activity of Gemcitabine against Bladder Cancer Cells. Glycoconj J. 2013, 30: 423 6. Fan Jianhui,Wang Shujing,Yu Shengjin,He Jingna,Zheng Weilong,Zhang Jianing*. Effects of down-regulation of lentivirus-mediated GnTⅣa on the proliferation and invasion of mouse hepatoma Hca-F cells. Chin J Cancer Biother, 2013, 20(6): 673-678. 7. Fan J., Wang S., Yu S., He J., Zheng W., Zhang J.*. N-acetylglucosaminyltransferase IVa regulates metastatic potential of mouse hepatocarcinoma cells through glycosylation of CD147. Glycoconj J. 2012, 29(5-6), 323-334. 8. J. Fan, J. He, S. Wang, Y. Guo, Y. Dang, S. Yu, J. Zhang*. Expression of N-actylglucosaminyltransferase IVa Regulates Invasion of Mouse Hepatocarcinoma Cells in vitro. Glycoconj J. 2011, 28: 263.

学术兼职

Member of Chinese society of Biochemistry and molecular biology (CSBMB) Vice Chairman of Education and Training Youth Committee, CSBMB

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