个人简介
刘淑清
职务: 教授
专业: 生物化学与分子生物学
Education/Working Experience
2007/03 - present, Dalian Medical University (Dalian, LN, China), Department of Biochemistry, Professor
2005/07-2007/03, Case Western Reserve University (Cleveland, NY, USA), Center for proteomics, Associate Research
2003/07-2005/06, Einstein College of medicine (Bronx, NY, USA), Department of Biochemistry, Associate Research
2001/10-2003/06, University of Massachusetts Medical School (Worcester, MA, USA), Program in Molecular Medicine, postdoctoral fellow.
2000/08-2001/08, CEA/CNRS (Grenoble, France), Department of bioinorganic chemistry, postdoctoral fellow.
1995/09-2000/07, Jilin University (Changchun, JL, China), Department of chemistry, Ph. D.Participation in the Academic Community
2009/03 – present, member of Chinese Society for Biochemistry and Molecular Biology
Research Projects/Grants
Signaling pathway mediatedby Crk regulate tumor lymphatic metastasis and its application in the diagnosis and treatment of tumors. Grants by National NaturalScience Foundation of China 81272186.
Study on the malignant behavior and molecular mechanism of CrkL in human chronic myeloid leukemia K562 cells. Grants byNatural Science Foundation of Liaoning Province 2015020266.
Admission Plan/Requirements
1 MS Graduate
1 Ph.D. Graduate
近期论文
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1. Shuqing Liu#, Chunmei Guo#, Jiasheng Wang#, Bo Wang, Houbao Qi, Ming-Zhong Sun. ANXA11 regulates the tumorigenesis, lymph node metastasis and 5-fluorouracil sensitivity of murine hepatocarcinoma Hca-P cells by targeting c-Jun. Oncotarget, 2016, has been accepted for publication. IF: 6.359
2. Boya Peng#, Shuqing Liu#, Chunmei Guo, Xujuan Sun, Ming-Zhong Sun*. ANXA5 level is linked to in vitro and in vivo tumor malignancy and lymphatic metastasis of murine hepatocarcinoma cell. Future Oncology, 2016, 12(1): 31-42. IF: 2.477
3. Chunmei Guo, Shuqing Liu*, Panpan Dong, Dongting Zhao,Chengyi Wang, Zhiwei Tao, Ming-Zhong Sun*. Akbu-LAAO exhibits potent anti-tumor activityto HepG2 cells partially through produced H2O2 via TGF-β signal pathway. Scientific Reports, 2015, 5: 18215. IF:5.578
4. Shuqing Liu, Jiasheng Wang, Chunmei Guo, Houbao Qi, Ming-Zhong Sun*. Annexin A11 knockdown inhibits in vitro proliferation and enhances survival of Hca-F cell via Akt2/FoxO1 pathway and MMP-9 expression. Biomedicine & Pharmacotherapy, 2015, 70: 58-63. IF: 2.023
5. Qiuyue Lin, Ming-Zhong Sun, Chunmei Guo, Ji Shi, Xin Chen, Shuqing Liu*. CRKL overexpression suppresses in vitro proliferation, invasion and migration of murine hepatocarcinoma Hca-P cells. Biomedicine & Pharmacotherapy, 2015, 69: 11-17. IF: 2.023
6. Ji Shi, Longlong Meng, Ming-Zhong Sun*, Chunmei Guo, Xujuan Sun, Qiuyue Lin, Shuqing Liu*. CRKL knockdown promotes in vitro proliferation, migration and invasion, in vivo tumor malignancy and lymph node metastasis of murine hepatocarcinoma Hca-P cells. Biomedicine & Pharmacotherapy, 2015, 71; 84-90. IF: 2.023
7. Ming-Zhong Sun, Yanhua Cui, Chunmei Guo, Baochang Zhao, Shuqing Liu*. rAdinbitor, a disintegrin from Agkistrodon halys brevicaudus stejneger, inhibits tumorigenicity of hepatocarcinoma via enhanced anti-angiogenesis and immunocompetence. Biochimie, 2015, 116: 34-42. IF: 2.963.
8. Shuqing Liu#，Chunmei Guo，Yimeng Guo，Hongshan Yu，Frederick Greenawayand Ming-Zhong Sun*. Comparative binding affinities of flavonoid phytochemicals with bovine serum albumin. Iranian Journal of Pharmaceutical Research, 2014, 13(3): 1019-1028. IF: 1.065
9. Boya Peng, Chunmei Guo, Hongwei Guan, Shuqing Liu*, Ming-Zhong Sun*. Annexin A5 as a potential marker in tumors. Clinica Chimica Acta, 2014, 427: 42–48. IF: 2.824.
10. Chunmei Guo#, Shuqing Liu#, Frederick Greenaway, Ming-Zhong Sun*. Potential role of annexin A7 in cancers. Clinica Chimica Acta, 2013, 423: 83–89. IF: 2.824
11. Chunmei Guo, Shuqing Liu*, Ming-Zhong Sun*. Sequence and bioinformatic characterization of expressed sequence tags originated from Gloydius shedaoensis shedaoensis venom gland. The Anatomical Record, 2013, 296: 807–814. IF:1.542
12. Na Wu, Shuqing Liu*, Chunmei Guo, Zhijie Hou, Ming-Zhong Sun*. The role of Annexin A3 playing in cancers. Clinical and Translational Oncology, 2013, 15(2): 106-110. IF: 2.077.
13. Chunmei Guo, Shuqing Liu*, Ming-Zhong Sun*. Novel insight into the role of GAPDH playing in tumor. Clinical and Translational Oncology, 2013, 15(3): 167-172. IF: 2.077.
14. Xiaohui Zhang#, Shuqing Liu#, Chunmei Guo, Junwei Zong, Ming-Zhong Sun*. The association of annexin A2 and cancers. Clin Transl Oncol, 2012, 14: 634-640. IF: 2.077
15. Shuqing Liu, Chunmei Guo, Dachang Wu, Yixin Ren, Ming-Zhong Sun*, Peng Xu. Protein indicators for HaCaT cell damage induced by UVB irradiation. Journal of Photochemistry and Photobiology B:Biology, 2012, 114: 94-101. IF: 2.96
16. Yiwen Yao#, Shuqing Liu#, Chunmei Guo, Chunyan Zhang, Dachang Wu, Yixin Ren, Hong-Shan Yu, Ming-Zhong Sun*, and Hailong Chen. Function-structural study of anti-LDL-oxidation effects of flavonoid phytochemicals. Journal of Medicinal Plants Research, 2012, 6(49): 5895-5904.
17. Chunmei Guo#, Shuqing Liu#, Yiwen Yao, Qiaoqiao Zhang, Ming-Zhong Sun*. Past decade study of snake venom L-amino acid oxidase. Toxicon, 2012, 60: 302-311. IF: 2.492
Shuqing Liu#, Fan Yang#, Qiaoqiao Zhang, Ming-Zhong Sun*, Ying Gao, Shujuan Shao. ‘‘Anatomical’’ view of the protein composition and protein characteristics for Gloydius ShedaoensisSnake venom via proteomics approach. The Anatomical Record, 2011, 294: 273–282. IF: 1.542
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