个人简介
王茜,博士,副教授,硕士研究生导师。现在大连医科大学基础医学院细胞生物教研室工作。承担了留学生、研究生、七年制、本科等多个层次的《细胞生物学》和《医学遗传学》等课程的理论及实验教学工作。曾获基础医学院青年教师讲课大赛第二名,年度最受欢迎的授课教师,基础医学院优秀共产党员等荣誉称号。主编和参编了《医学细胞生物学》,《细胞生物学简明教程》等书籍。
主要从事肿瘤分子生物学方面的研究工作。多年来致力于白藜芦醇抗髓母细胞瘤分子机制方面的研究。揭示白藜芦醇能以Fas非依赖性途径抑制髓母细胞瘤细胞生长并诱导其分化和凋亡。阐明白藜芦醇抗髓母细胞瘤的信号网络作用特点。主持省教委一般项目一项(2008年),辽宁省自然科学基金一项(2013年),二项国家自然科学基金项目执行负责人,获得省自然科学二等奖一项,中华医学会三等奖,发明专利2项,近年来以第一作者发表SCI论文3篇。
近期论文
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[1] Zhi-Li Liu, Hong Li, Jia Liu, Mo-Li Wu, Xiao-Yan Chen,Li-Hong Liu , Qian Wang Inactivated Wnt Signaling in Resveratrol-suppressed Epidermal Squamous Cancer Cells and Its Biological Implication. Oncology Reports(accepted,通讯作者)
[2] Fu Yuan-Shan, Wang Qian, Ma Jing-Xin, Yang Xiang-Hong, Wu Mo-Li, Zhang Kai-Li, Kong Qing-You, Chen Xiao-Yan, Sun Yuan, Chen Nan-Nan, Shu Xiao-Hong, Li Hong, Liu Jia. CRABP-II methylation: A critical determinant of retinoic acid resistance of medulloblastoma cells. Molecular Oncology(IF6.379). 6:48–61,2012.(共同第一作者).
[3] Shu Xiao-Hong, Li Hong, Sun Xiao-Xin, Wang Qian, Sun Zheng, Wu Mo-Li, Chen Xiao- Yan, Li Cong, Kong Qing-You, Liu Jia. Metabolic patterns and biotransformation activitiesof resveratrol in human glioblastoma cells: relevance with therapeutic efficacies. PLoS One(IF3.534). 6(11):e27484, 2011.
[4] Sun Yuan, Gao Xue, Liu Jia, Kong Qing-You, Chen Xiao-Yan, Wang Qian, Cheng Yi-Fan, Qu Xiao-Xia, Li Hong. Differential Notch1 and Notch2 expression and frequent activation of Notch signaling in gastric cancers. Arch Pathol Lab Med. (IF2.577)135:451-458, 2011.
[5] Wen Shu, Li Hong, Wu Mo-Li, Fan Shao-Hua, Wang Qian, Shu Xiao-Hong, Kong Qing-You, Chen Xiao-Yan and Liu Jia. Inhibition of NF-B Signaling Commits Resveratrol- treated Medulloblastoma Cells to Apoptosis without Neuronal Differentiation J Neurooncol(IF5.025). 104:169–177, 2011.
[6] Shu Xiao-Hong, Li Hong, Sun Zheng, Wu Mo-Li, Ma Jing-Xin, Wang Jian-Min, Wang Qian, Sun Yuan, Fu Yuan-Shan, Chen Xiao-Yan, Kong Qing-You, Liu Jia. Identification of metabolic pattern and bioactive form of resveratrol in human medulloblastoma cells. Biochem Pharmacol.( IF4.650 )79:1516-25,2010.