当前位置: X-MOL首页全球导师 国内导师 › 张续勐

个人简介

张续勐,男, 新疆博湖人. 张续勐,男,1989年9月生。2008年9月-2012年6月在中山大学生命科学学院逸仙班生物技术专业学习,获得理学学士学位;2012年9月-2017年6月在中山大学有害生物控制与资源利用国家重点实验室陈瑶生教授团队直博,获得理学博士学位;2017年7月至今从事中山大学-深圳金新农科技股份有限公司基地博士后研究工作,合作导师是陈瑶生和魏泓教授。博士和博后期间针对中国地方猪种与西方瘦肉型猪种产肉量差异的原因利用全基因组甲基化、转录组、蛋白组和ChIP-seq等多组学方法,结合细胞和活体实验,初步揭示了产肉量不同猪种胚胎期初级肌纤维形成时间差异的分子机制。在FASEB Journal, BMC Genomics和Journal of Animal Science等SCI期刊上发表论文14篇,其中第一作者5篇;申请发明专利1项;并获得中国博士后科学基金面上项目二等资助。教育背景: 时 间 大 学 专 业 学 位 2012.09-2017.07 中山大学 遗传学 博士 2008.09-2012.07 中山大学 生物技术 学士 l 工作经历: 时 间 地 点 工作/职务 2019.06-至今 仲恺农业工程学院 特聘副教授 2017.07-2019.05 中山大学-深圳金新农科技股份有限公司 博士后 l 主要奖项: 1、 2016年度中山大学过渡期间博士奖学金 2、 2015年度有害生物控制与资源利用国家重点实验室杰出研究生学术奖主 l 科研项目: 项目类别,批准号,名称,研究起止年月,获资助金额,项目状态(已结题或在研等): 中国博士后科学基金面上项目二等资助,2018M633233,利用基因编辑猪肌卫星细胞研究Zfp422基因对成肌的调控机制,5万元,2018/05-2019/05,结题,主持。专利:莫德林; 张续勐; 陈瑶生; 刘小红; 何祖勇; 丛佩清; 邱柏钦; 郭慈琳, 一种通过延迟基因的表达时间来提高猪瘦肉产量的方法, 2017.4.28, 中国, 201710295934.6

研究领域

主要研究方向:动物功能基因组学

1. 动物功能基因组学 2. 动物肌肉脂肪骨骼发育 3. 动物遗传学

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

主要论文:(以发表时间为序,*为通信作者,+为共同第一作者;JCR分区采用中科院系统) 英语文章: 2019 1, Xumeng Zhang+, Shufang Cai+, Luxi Chen, Renqiang Yuan, Yaping Nie, Suying Ding, Ying Fang, Qi Zhu, Keren Chen, Hong Wei, Yaosheng Chen, Delin Mo. Integrated miRNA-mRNA transcriptomic analysis reveals epigenetic mediated embryonic muscle growth differences between Wuzhishan and Landrace pigs[J]. Journal of Animal Science,2019,97:1967–1978. IF=1.714. JCR一区 2, Xumeng Zhang+, Yaping Nie+, Shufang Cai+, Suying Ding, Bingqiang Fu, Hong Wei, Luxi Chen, Xiaohong Liu, Minggui Liu, Renqiang Yuan, Boqing Qiu, Zuyong He, Peiqing Cong, Yaosheng Chen, Delin Mo. Earlier demethylation of myogenic genes contributes to embryonic precocious terminal differentiation of myoblast in miniature pigs[J]. The FASEB Journal, 2019, 33 (8). IF=5.595. JCR一区 3, Luxi Chen, Yue Zhang, Hu Chen, Xumeng Zhang, Xiaohong Liu, Zuyong He, Peiqing Cong, Yaosheng Chen, and Delin Mo. Comparative transcriptome analysis reveals more complicated adipogenic process in intramuscular stem cells than that of subcutaneous vascular stem cells[J]. Journal of Agricultural and Food Chemistry, 2019,67, 16, 4700-4708. IF=3.412. JCR一区 2018 4, Renqiang Yuan+, Xumeng Zhang+, Ying Fang, Yaping Nie, Shufang Cai, Yaosheng Chen, Delin Mo. mir-127-3p inhibits the proliferation of myocytes by targeting KMT5a[J]. Biochemical and Biophysical Research Communications, 2018, 503(2):970-976. IF=2.559. JCR二区 2017 5,Shuihua Xie, Luxi Chen, Xumeng Zhang, Xiaohong Liu, Yaosheng Chen, Delin Mo. An integrated analysis revealed different microRNA-mRNA profiles during skeletal muscle development between Landrace and Lantang pigs. Scientific Reports, 2017 May 31;7(1):2516. IF=4.122 JCR二区 6,Zhuning Yuan, Yaosheng Chen, Xumeng Zhang, Xingyu Zhou, Mingsen Li, Hu Chen, Ming Wu, Ying Zhang, Delin Mo. Silencing myotubularin related protein 7 enhances proliferation and early differentiation of C2C12 myoblast[J]. Biochemical and Biophysical Research Communications,2017, 484(3):592-597. IF=2.371 JCR二区 8,Mian Liu, Xumeng Zhang*,An integrated analysis of mRNA-miRNA transcriptome data revealed hub regulatory networks in three genitourinary cancers,Biocell, 2017, 41(1).IF=0.118 JCR四区 9,Yaping Nie, Hu Chen, Cilin Guo, Zhuning Yuan, Xingyu Zhou, Ying Zhang, Xumeng Zhang. Palmdelphin promotes myoblast differentiation and muscle regeneration[J].Scientific Reports,2017, 7:41608. IF=5.228 2016 10,Xumeng Zhang, Yaosheng Chen, Jinchun Pan, Xiaohong Liu, Hu Chen, Xingyu Zhou,Zhuning Yuan, Xilong Wang, Delin Mo.iTRAQ-based quantitative proteomic analysis reveals the distinct early embryo myofiber type characteristics involved in landrace and miniature pig[J]. BMC Genomics, 2016, 17:137. IF=3.867 JCR一区 11, Hu Chen, Renqiang Yuan,Ying Zhang, Xumeng Zhang, Luxi Chen, Xingyu Zhou, Zhuning Yuan, Yaping Nie, Ming Li, Delin Mo, Yaosheng Chen.ATF4 regulates SREBP1c expression to control fatty acids synthesis in 3T3-L1 adipocytes differentiation[J]. BBA - Gene Regulatory Mechanisms, 2016,1859(11):1459-1469. IF=5.373 JCR一区 12,Xingyu Zhou, Mingsen Li, Huaxing Huang, Keren Chen, Zhuning Yuan, Yaping Nie, Hu Chen, Xumeng Zhang, Luxi Chen, Delin Mo, Yaosheng Chen. HMGB2 regulates satellite-cell-mediated skeletal muscle regeneration through IGF2BP2[J]. Journal of Cell Science,2016, 129(22):4305-4316. IF=4.706 JCR一区 2015 13, Ming Wu, Gongshe Yang, Yaosheng Chen, Xingyu Zhou, Hu Chen, Mingsen Li, Kaifan Yu, Xumeng Zhang, Shuihua Xie, Ying Zhang, Guiyan Chu, Delin Mo.CEP2 attentuates myoblast differentiation but does not affect proliferation[J].International Journal of Biological Sciences,2015,11:99-108.IF=4.372 2014 14,Hu Chen, Delin Mo, Ming Li, Yun Zhang, Luxi Chen, Xumeng Zhang, Mingsen Li, Xingyu Zhou, Yaosheng Chen.MiR-709 inhibits 3T3-L1 cell differentiation by targeting GSK3β of Wnt/β -catenin signaling pathway [J].Cellular Signalling,2014,26(11):2583-2589.IF=4.171

推荐链接
down
wechat
bug