欧阳津 - 北京师范大学

个人简介

欧阳津，女，49岁，比利时根特大学药学院药学博士，现为北京师范大学化学学院教授，博士生导师。化学实验教学中心主任。主要研究方向包括高效液相色谱、毛细管电泳分离方法学及在药物及其他生物化合物分析中的应用；聚丙烯酰胺凝胶电泳及免疫电泳分离-发光成像技术分析蛋白质及其结合物等。已在国际刊物Analytical Chemistry,Proteomics, J. Chromatography A, Electrophoresis, Clin. Chem.,Trends in Analytical Chemistry, Anal. Chim. Acta，Talanta, Eur. J. Clin. Chem. Clin. Biochem.，Am. J. Clin. Nutr.，以及“化学学报”“分析化学”等刊物上共发表论文50余篇。主编及参编《液相色谱检测方法》，《生物化学实验技术》及《化学测量实验》分别由化学工业出版社，科学出版社出版。主持国家自然科学基金项目 3 项（小额预研1项、面上项目2项），及科技部中国-比利时政府国际合作项目1项。

研究领域

高效液相色谱法拆分手性药物及药代动力学的研究纳米材料在高效毛细管电泳中的应用研究蛋白质的聚丙烯酰胺凝胶电泳化学发光成像法研究青铜器、字画等古文物的鉴定

近期论文

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Sun, F. F.; Zhao, S. N.; Peng, M. S.; Fu, Q.; Gao, H. M; Jia, Y. J.; Na, N.; Ouyang, J.* Sequencing of Small DNA Fragments with Aggregated-Induced-Emission Molecule-Labeled Nucleotides. Anal. Chem. 2020, 92(10), 7179-7185 Fang, Z. Y.;Wang, R. H.; Zhao, H. S.; Yao, H.; Ouyang, J*; Zhang, X.R. Mannose Promotes Metabolic Discrimination Osteosarcoma Cells at Single-Cell Level by Mass Spectrometry. Anal. Chem. 2020, 92(3), 2690-2696 Peng, M. S; Sun, F. F.; Na, N.; Ouyang, J.* Target-Triggered Assembly of Nanogap Antennas to Enhance the Fluorescence of Single Molecules and Their Application in MicroRNA Detection. Small 2020, 16(19), 8.2000460. Jia, Y. J; Shen, X. T; Sun, F. F.; Na, N.; Ouyang, J.* Metal-DNA coordination based bioinspired hybrid nanospheres for in situ amplification and sensing of microRNA. J. Mater. Chem. B., 2020. 8,11074-11078 Wang F. Y.; Na N.; Ouyang J.* A catalytic-regulated gold nanorods etching process as a receptor with multiple readouts for protein detection. Sens. Actuator B-Chem. 2020, 318, 128-215 Cui, Y.Y.; Yuan, C.; Tan, H. W.; Zhang, Z. B.; Jia, Y. J.; Na, N.; Ouyang, J.* Plasmon‐Enhanced Fluorescent Sensor based on Aggregation‐Induced Emission for the Study of Protein Conformational Transformation, Adv. Funct. Mater. 2019, 29, 1807211. Wang, R. H.; Zhao, H. S.; Zhang, X. C.; Zhao, X.; Song, Z.; Ouyang, J.* Metabolic Discrimination of Breast Cancer Subtypes at the SingleCell Level by Multiple Microextraction Coupled with Mass Spectrometry, Anal. Chem. 2019, 91, 3667-3674. Peng, M. S.; Na, N.; Ouyang, J.* A Fluorescence Light‐Up Silver Nanocluster Beacon Modulated by Metal Ions and Its Application in Telomerase‐Activity Detection, Chem. Eur. J.,2019, 25, 3598-3605. Peng, M. S.; Fang, Z. Y.; Na, N.; Ouyang, J.* A versatile single-molecule counting-based platform by generation of fluorescent silver nanoclusters for sensitive detection of multiple nucleic acids, Nanoscale 2019, 11, 16606-1661 Peng, M. S.; Wang Y.; Fu Q.; Sun F. F.; Na N.; Ouyang J.* Melanosome-Targeting Near-Infrared Fluorescent Probe with Large Stokes Shift for in Situ Quantification of Tyrosinase Activity and Assessing Drug Effects on Differently Invasive Melanoma Cells, Anal. Chem. 2018, 90(10), 6206-6213 Niu, C. X.; Peng, M. S.; You, Y.; Wang, R. H.; Jia, Y. J.; Xie, T. X.; Wang, J. Y.; Na, N.; Ouyang, J.* A comparative study of plasmonic-enhanced single-molecule fluorescence induced by gold nanoantennas and its application for illuminating telomerase, Chem. Commun.2017, 53(41), 5633-5636. Song, Q. W.; Wang, R. H.; Sun, F. F.; Chen, H. K.,; Wang, Z. M.K.; Na, N.; Ouyang, J.* A nuclease-assisted label-free aptasensor for fluorescence turn-on detection of ATP based on the in situ formation of copper nanoparticles, Biosens. Bioelectron. 2017, 87, 760-763. Sun F. F.; You, Y.;Liu J.; Song, Q. W.; Shen X. T.; Na N.; Ouyang, J.* DNA Three-Way Junction for Differentiation of Single-Nucleotide Polymorphisms with Fluorescent Copper Nanoparticles, Chem. Eur. J.2017, 23(29), 6979-6982. Niu, C. X.; Song, Q. W; He, Gen; Na, Na; Ouyang, J* Near-Infrared-Fluorescent Probes for Bioapplications Based on Silica-Coated Gold Nanobipyramids with Distance-Dependent Plasmon-Enhanced Fluorescence, Anal. Chem. 2016, 88(22), 11062-11069 Wang L.; Song Q. W.; Liu Q. L.; He D. C.; and Ouyang J*. Plasmon-Enhanced Fluorescence-based Core–Shell Gold Nanorods as a Near-IR Fluorescent Turn-on Sensor for the Highly Sensitive Detection of Pyrophosphate in Aqueous Solution. Adv. Funct. Mater. 2015, 25, 7017.