个人简介

1979 B.S. Physics, Louisiana State University;1985 M.D., Johns Hopkins University School of Medicine; 1987 Ph.D. Medical Physics/Medical Engineering, Massachusetts Institute of Technology; 1988 Postdoctoral Fellow, Massachusetts Institute of Technology; 1989-1994 NIH Postdoctoral Fellow, Dept. of Cell Biology and Neurobiology, Stanford University; 1994-2000 Assistant Professor, Dept. of Physiology and Biophysics and Center for Biomedical Engineering, University of California-Irvine: 1995 Searle Scholar Award; 1995 Beckman Young Investigator Award; 2000-2004 Associate Professor, Dept. of Physiology and Biophysics and Dept. of Biomedical Engineering, University of California-Irvine; 2003 UCI Midcareer Research Award; 2004 UCI College of Medicine Excellence in Teaching Award; 2004-2007 Professor, Dept. of Physiology and Biophysics, and Dept. of Biomedical Engineering,University of California-Irvine; 2005-2007 Professor, Dept. of Chemistry, and Dept. of Chemical Engineering and Materials Science, University of California-Irvine; 2007-current, Distinguished Professor, Dept. of Chemistry, University of North Carolina-Chapel Hill; also Professor & Chair, UNC/NCSU Joint Department of Biomedical Engineering; Fellow, American Institute for Medical and Biological Engineering (AIMBE), 2010; Fellow, American Association for the Advancement of Science, 2014

研究领域

Analytical/Biochemistry & Chemical Biology/Materials/Polymers & Nanoscience

Signaling in Single Cells, Microfabricated Systems for Cellular Analysis

近期论文

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Phillips, R.M., Dailey, L.A.,Bair, E., Samet, J.M., Allbritton, N.L. Ex Vivo Chemical Cytometric Analysis of Protein Tyrosine Phosphatase Activity in Single Human Airway Epithelial Cells. 2014. Anal. Chem. 86:1291-1297.  Kovarik, M.L., Dickinson, A.J., Roy, P., Poonnen, R.A., Fine, J.P., and Allbritton, N.L. 2014. Response of Single Leukemic Cells to Peptidase Inhibitor Therapy Across Time and Dose Using a Microfluidic Device. Integr. Biol. 6: 164-174  Gach, P.C., Attayek, P.J., Whittlesey, R.L., Yeh, J.J., Allbritton, N.L. 2014. Micropallet Arrays for the Capture, Isolation and Culture of Circulating Tumor Cells from Whole Blood of Mice Engrafted with Primary Human Pancreatic Adenocarcinoma. Biosensors & Bioelectronics. 54: 476-483.  Huang, W., Proctor, P., Sims, C.E., Allbritton, N.L., Zhang, Q. 2014. Fluorous Enzymatic Synthesis of Phosphatidylinositides. Chem. Commun. 50: 2928-2931.  Wang, Y., Ahmad, A.A., Sims, C.E., Magness, S.T., Allbritton, N.L. 2014. In vitro generation of colonic epithelium from primary cells guided by microstructures. Lab on Chip. 14: 1622 - 1631.  Ahmad, A.A., Wang, Y., Gracz, A., Sims, C.E., Magness, S.T., Allbritton, N.L. 2014. Optimization of 3-D Organotypic Colon Cultures on Chip. J Bioeng. 8:9-19.  Grohman, J.K.,Gorelick, R.J., Kottegoda, S., Allbritton, N.L., Rein, A., Weeks, K.M. 2014. A retroviral genome packaged in a kinetically trapped intermediate state. J. Virology. In Press.  Proctor, A., Herrera, G.S., Wang, Q., Lawrence, D.S.,Yeh, J.J., Allbritton, N.L. 2014. Measurement of Protein Kinase B Activity in Single Primary Human Pancreatic Cancer Cells. Anal. Chem. 86:4573-4580.  Shah, P.K., Herrera, G.S., Sims, C.E., Yeh, J.J., Allbritton, N.L. 2014. Small Sample Sorting of Primary Adherent Cells by Automated Micropallet Imaging and Release. Cytometry. In Press.  Shah, P.K., Walker, M.P., Sims, C.E., Major, M.B., Allbritton, N.L. 2014 Characterization of β-catenin activated reporter dynamics and evolution by massively parallel clonogenic screening. Integr. Biol. 6:673-684.  Dickinson, A.J., Hunsucker, S.A., Armistead, P.M., Allbritton, N.L. 2014. Single-Cell Sphingosine Kinase Activity Measurements in Primary Leukemia. Anal. Bioanal. Chem. In press