个人简介
1、1991-1995年, 山东大学化学系,理学学士。 2、 1997-2000年, 中国农业科学院, 生物物理学专业,理学硕士。 3、 2000-2003年,中国科学院生态环境研究中心,环境科学专业,理学博士。 4、 2003年-,北京科技大学。 5、 2006年8月-2007年8月,美国Wayne State University医学院访问学者。
研究领域
食品与环境中污染物的生物检测与分离技术研究;环境毒理学研究;抗肿瘤药物研究
食品与环境中污染物的生物检测与分离技术研究;环境毒理学研究;抗肿瘤药物研究
近期论文
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1、时国庆,李栋,卢晓珅,王海鸥,刘丽琴,魏巍,宣劲松,环境内分泌干扰物质的健康影响与作用机制,环境化学,2011. 30(1): 211-223. (主编约稿) 2、SHI GuoQing, SUN Qing, YANG HuanJie, DOU QingPing,DENG QianMin, WANG HaiOu & ZHONG GuangRong,Molecular modeling for the interaction between proteasome beta 5 subunit and organotin compounds, Sci China Chem, 2010, 53(11): 2387–2393 3、CHEN Xi, SHI GuoQing, ZHONG GuangRong, CHEN Juan, LIN Sen & SUN Qing, Triphenyltin inhibition of the proteasome activity and its influence on substrate protein levels in nerve cells. Chinese Sci Bull, 2010, 55: 22-26 4、Guoqing Shi, Di Chen, Guangshu Zhai, Marina S. Chen, Qiuzhi Cindy Cui, Qunfang Zhou, Bin He, Q. Ping Dou and Guibin Jiang. (2009). The Proteasome Is a Molecular Target of Environmental Toxic Organotins. Environmental Health Perspectives 117:379-386(Science selection, EHP117:A116) 5、Congde Hou, Guoqing Shi, Wai Har Lam, Di Chen, Quizhi Cindy Cui, Q. Ping Dou and Tak Hang Chan. Semi-synthesis and proteasome inhibition of D-ring deoxy analogs of (-)-epigallocatechin gallate (EGCG), the active ingredient of green tea extract. Can. J. Chem. 2008, 86:495-502 6、Yang Huanjie, Shi Guoqing, Dou Qingping, The tumor proteasome is a primary target for the natural anticancer compound Withaferin A isolated from "Indian winter cherry". Mol Pharmacol. 2007, 71(2):426-437 7、Landis-Piwowar KR, Huo C, Chen D, Milacic V, Shi G, Chan TH, Dou QP. A novel prodrug of the green tea polyphenol (-)-epigallocatechin-3-gallate as a potential anticancer agent. Cancer Res. 2007 67(9):4303-10 8、Jing Shao, Guoqing Shi, Xinglong Jin, Maoyong Song, Jianbo Shi, Guibin Jiang, Preliminary survey of estrogenic activity in part of waters in Haihe River, Tianjin,Chinese Science Bullitin, 2006,50, 2565-2570 9、Jing Shao, Guoqing Shi, Maoyong Song, Guibin Jiang,Development and validation of an enzyme-linked immunosorbent assay for vitellogenin in Chinese loach (Misgurnus angaillicaudatus),Environ. Intern., 2005, 31(5):763-770 10、Jing Shao, Guoqing Shi, Guibin Jiang, Jingfu Liu, A rapid two-step chromatographic method for the quantitative determination of vitellogenin in fish plasma. Anal. Bioanal. Chem. 2004, 378, 615-620 11、 Guoqing Shi, Jing Shao, Guibin Jiang, Qianxing Wang, Yiqaing Lu, Jingfu Liu, Jiemin Liu, Membrane chromatography for the rapid purification of vitellogenin from fish plasma.J. Chromatogr. B, 2003, 785:361-368 12、Guoqing Shi, Guibin Jiang, A Dip-and-Read Test Strip for the Determination of Mercury(II) Ion in Aqueous Samples Based on Urease Activity Inhibition. Anal. Sci. 2002, 18, 1215-1219