个人简介
汉族,讲师,理学博士(中国科学院生物物理研究所),生物学博士后(中国人民解放军军事医学研究院),现任生命与环境科学学院(转化神经科学中心)教师。
研究领域
神经退行性疾病的理论和应用研究:从天然免疫信号通路和神经炎症入手,以民族药单一组分为药物库,聚焦阿尔兹海默病、缺血性中风和抑郁症等神经退行性疾病的分子机制研究和新药筛选
近期论文
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1.Yajin Liao, Yuan Dong, and Jinbo Cheng. The function of the mitochondrial calcium uniporter in neurodegenerative disorders.Int. J. Mol. Sci. 10;18(2). pii: E248. ( 2017).
2.Cheng Jinbo#,Liao Yajin#(co-first), Xiao Lei, Peng Shengyi, Xuyun, Yuan Zengqiang. Autophagy regulates MAVS-mediated microglial activation in a phosphorylation dependent manner.Cell death and differ. 24(2):276-287 (2017).
3.Jinghan Wang#, Shucheng Chen#,Yajin Liao#(co-first), Enyu Zhang, Shuo Feng, Shaoxiong Yu, Lian-Feng Li, Wen-Rui He, Yongfeng Li, Yuzi Luo, Yuan Sun, Xiao Wang, Muhammad Munir, Su Li, Hua-Ji Qiu. Mitogen-activated protein kinase kinase 2 (MEK2), a novel E2-interacting protein, promotes the growth of classical swine fever virus via attenuation of IFN-JAK-STAT pathway.J Virol. 01407-16(2016).
4.Cheng Jinbo#,Liao Yajin#(co-first), Zhou Lujun, Peng Shengyi, Chen Hong, Yuan Zengqiang. Amplified RLR signaling activation through an interferon-stimulated gene-endoplasmic reticulum stress-mitochondrial calcium uniporter protein loop.Sci Rep-UK. 6:20158 (2016).
5.Liao Yajin, Hao Yuming, Chen Hong, He Qing, Yuan Zengqiang, Cheng Jinbo. Mitochondrial calcium uniporter protein MCU is involved in oxidative stress-induced cell death.Protein&Cell. 6(6):434-42 (2015).
6.廖亚金,李素,贺番,何文瑞,董泓,冯烁,孙元,仇华吉.猪外周血单个核细胞cDNA酵母表达文库的构建及与猪瘟病毒E2蛋白相互作用细胞蛋白的筛选[J].中国预防兽医学报,35(9):707-710 (2013).
7.Rong Wu, Ang Li, Bao-Fa Sun, Jian-Guang Sun, Jinhua Zhang, Ting Zhang, Yusheng Chen, Yujie Xiao, Yuhao Gao, Qingyang Zhang, Jun Ma, Xin Yang,Yajin Liao, Wei-Yi Lai, Xiaolong Qi, Shukung Wang, Yousheng Shu, Hailin wang, fengchao Wang, and Yun-Gui Yang, Zengqiang Yuan. A novel m6A reader Prrc2a controls oligodendroglial specification and myelination.Cell Res. 29(1):23-41 (2018).
8.Jun Ma, Xiaolong Qi, Chaojuan Yan, Ruiyuan Pan, Shukun Wang, Junbing Wu, Li Huang, Hong Cheng, Jinbo Cheng, Rong Wu,Yajin Liao, Lanqun Meng, Fengchao Wei, Zhiying Wu, Jianxiong An, Yun Wang, Xia Zhang, Chen Zhang, Zengqiang Yuan. Calhm2 governs astrocytic ATP releasing in the development of depression-like behaviors.Mol Psychiatry. 23(4):1091 (2017).