陈艳华 - 中央民族大学 - 生命与环境科学学院

个人简介

汉族，副研究员，理学博士，硕士生导师，入选北京市高校青年英才计划（2013年），中央民族大学高层次优秀人才（2019年）。 2003年于吉林大学取得学士学位，2006年于吉林大学取得硕士学位，2009年于北京协和医学院药物研究所取得博士学位，随后留所任助理研究员（至2014年7月），副研究员，硕士生导师。2019年6月以高层次优秀人才引进至中央民族大学。任中国医师协会癌症代谢与治疗专业委员会委员，中国生物物理学会代谢组学分会理事。任Analyst、Frontiers in Pharmacology、Bioanalysis、Analytical letters等国际期刊同行评阅人。发表SCI收录论文30余篇；申请专利2项，软件著作权1项。获中国分析测试协会科学技术奖（CAIA奖）一等奖（第二完成人）。讲授课程质谱分析的原理及应用：代谢组学中的质谱分析（北京协和医学院）主持教学和科研项目国家重点研发计划（234万）：子任务负责人（2018-2022）国家自然科学基金青年项目（25万）：主持（2015-2017）北京市高校青年英才计划（15万）：主持（2013-2015） 863计划项目-课题1（1021万）：主要参与人（2014-2016）国家自然科学基金委重点项目（300万）：主要参与人（2014-2018）

研究领域

代谢组学分析新方法及其在重大疾病中的应用研究；定量代谢组学分析新方法研究；药物代谢组学和药物体内代谢过程研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

A sensitive on-tissue chemical derivatization-mass spectrometry imaging method for the quantitative visualization of helicid in mice Chemical Profiling and Quantitative Analysis on the Aqueous Extract of Pimpinella anisum Fruit by LC-MS/MS Comparison of Local Metabolic Changes in Diabetic Rodent Kidneys Using Mass Spectrometry Imaging IDO1 Activity Predicts Lung Toxicity in Patients with Unresectable Stage III NSCLC and Chemoradiotherapy Metabolomics and integrated network pharmacology analysis reveal that ginkgolides act as potential active anticancer components by regulating one-carbon metabolism Dynamic change of IDO1 activity predicts survival in patients with unresectable stage III NSCLC and chemoradiotherapy Norm ISWSVR: A Data Integration and Normalization Approach for Large-Scale Metabolomics Comprehensive quantitative method for neurotransmitters to study the activity of a sedative-hypnotic candidate using microdialysis and LC×LC-MS/MS Comprehensive Quantitative Method for Neurotransmitters to Study the Activity of a Sedative-Hypnotic Candidate Using Microdialysis and Lc×Lc-Ms/Ms Multidimensional molecular differences between artificial cultivated and wild Artemisia rupestris L. based on metabolomics–transcriptomics integration strategy Spatially Resolved Metabolomics Based on Air-Flow-Assisted Desorption Electrospray Ionization–Mass Spectrometry Imaging Reveals Region-Specific Metabolic Alterations in Diabetic Encephalopathy Spatial-resolved metabolomics reveals tissue-specific metabolic reprogramming in diabetic nephropathy by using mass spectrometry imaging Mapping Metabolic Networks in the Brain by Ambient Mass Spectrometry Imaging and Metabolomics Multidimensional molecular differences between artificial and wild Artemisia rupestris L. A targeted neurotransmitter quantification and nontargeted metabolic profiling method for pharmacometabolomics analysis of olanzapine by using UPLC-HRMS Strategy for Global Profiling and Identification of 2- and 3-Hydroxy Fatty Acids in Plasma by UPLC-MS/MS Development of a high-coverage metabolome relative quantitative method for large-scale sample analysis Development of methionine methylation profiling and relative quantification in human breast cancer cells based on metabolic stable isotope labeling Whole-body spatially-resolved metabolomics method for profiling the metabolic differences of epimer drug candidates using ambient mass spectrometry imaging Spatially resolved metabolomics to discover tumor-associated metabolic alterations Biotransformation-based metabolomics profiling method for determining and quantitating cancer-related metabolites Development of a Metabolic Pathway-Based Pseudo-Targeted Metabolomics Method Using Liquid Chromatography Coupled with Mass Spectrometry Development of Simultaneous Targeted Metabolite Quantification and Untargeted Metabolomics Strategy Using Dual-column Liquid Chromatography Coupled with Tandem Mass Spectrometry Development of a Data-Independent Targeted Metabolomics Method for Relative Quantification Using Liquid Chromatography Coupled with Tandem Mass Spectrometry Comparison of Multiple Ionization Methods Coupled with Liquid Chromatography-Mass Spectrometry inLipidomics Study of Serum Samples LC-MS-based metabolomics reveals metabolic signatures related to glioma stem-like cell self-renewal and differentiation Systematic evaluation of serum and plasma collection on the endogenous metabolome Mass spectrometry in metabolomics: What lies ahead Supplementary Information Global metabolomics reveals potential urinary biomarkers of esophageal squamous cell carcinoma for diagnosis and staging OPEN Methods used to increase the comprehensive coverage of urinary and plasma metabolomes by MS Optimization and Evaluation Strategy of Esophageal Tissue Preparation Protocols for Metabolomics by LC?MS Targeted Data-Independent Acquisition and Mining Strategy for Trace Drug Metabolite Identification Using Liquid Chromatography Coupled with Tandem Mass Spectrometry Human Metabolic Responses to Chronic Environmental Polycyclic Aromatic Hydrocarbon Exposure by a Metabolomic Approach Plasma metabolome analysis by integrated ionization rapid-resolution liquid chromatography/tandem mass spectrometry Combination of Injection Volume Calibration by Creatinine and MS Signals' Normalization to Overcome Urine Variability in LC-MS-Based Metabolomics Studies Global and Targeted Metabolomics of Esophageal Squamous Cell Carcinoma Discovers Potential Diagnostic and Therapeutic Biomarkers Assessment of data pre-processing methods for LC-MS/MS-based metabolomics of uterine cervix cancer Assessment of data pre-processing methods for LC-MS/ MS-based metabolomics of uterine cervix cancer Global and Targeted Metabolomics of Esophageal Squamous Cell Carcinoma Discovers Potential Diagnostic and Therapeutic Biomarkers Global and Targeted Metabolomics of Esophageal Squamous Cell Carcinoma Discovers Potential Diagnostic and Therapeutic Biomarkers LC-MS/MS-based Plasma Metabonomics Delineate the Effect of Metabolites' Stability on Reliability of Potential Biomarkers. Integrated rapid resolution liquid chromatography-tandem mass spectrometric approach for screening and identification of metabolites of the potential anticancer agent 3,6,7-trimethoxyphenanthroindolizidine in rat urine Analysis of multiplex endogenous estrogen metabolites in human urine using ultra-fast liquid chromatography-tandem mass spectrometry: A case study for breast cancer Time-Course Changes in Potential Biomarkers Detected Using a Metabonomic Approach in Walker 256 Tumor-Bearing Rats Integrated Ionization Approach for RRLC-MS/MS-based Metabonomics: Finding Potential Biomarkers for Lung Cancer RRLC-MS/MS-based metabonomics combined with in-depth analysis of metabolic correlation network: Finding potential biomarkers for breast cancer