个人简介
汉族,教授,硕士生导师,理学博士(北京大学),美国国立卫生研究院NIH博士后,中央民族大学2016年高层次杰出人才.现任中央民族大学转化神经科学中心负责人。两度获得美国国立卫生研究院“Fellows Award for Research Excellence”(2014-2015)。SCI期刊Journal of Molecular Neuroscience编委,Molecular Psychiatry等一系列SCI期刊特邀审稿人。入选2018年度北京市科技新星计划,主持国家自然科学基金青年项目和北京市自然科学基金面上项目。主要从事神经精神性疾病的研究工作,近三年以第一作者或者通讯作者在Nature子刊Molecular Psychiatry(IF=13.2)和JAMA子刊JAMA Pediatrics (IF =10.25)、JAMA Neurology (IF =10.03)等国际顶级刊物发表研究论文近20篇, SCI影响因子超过100分
讲授课程
神经生物学
主持教学和科研项目
2018年国家自然科学基金青年基金
2018年北京市自然科学基金
研究领域
神经营养因子在神经退行性疾病(如老年痴呆症)中的保护作用
抑郁症和精神分裂症的发病机制及生物标记物研究
环境因素对少数民族地区人群精神类疾病的影响
近期论文
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Cheng Y, Rodriguiz RM, Murthy SR, Senatorov V, Thouennon E, Cawley NX, Aryal DK, Ahn S, Lecka-Czernik B, Wetsel WC, Loh YP.Neurotrophic Factor-a1 prevents stress-induced depression through enhancement of neurogenesis and is activated by rosiglitazone.Mol Psychiatry.2015 Jun;20(6):744-54.(Nature子刊,IF=13.2,一区)
Qin XY, Cao C, Cawley NX, Liu TT, Yuan J, Loh YP,Cheng Y*. Decreased peripheral brain-derived neurotrophic factor levels in Alzheimer’s disease: a meta-analysis study (N=7,277).Mol Psychiatry. 2017 Feb;22(2):312-320.(Nature子刊,IF=13.2,一区)
Qin XY, Cao C, Wu HT, Loh YP,Cheng Y*.A meta-analysis of peripheral blood nerve growth factor levels in patients with schizophrenia.Mol Psychiatry. 2017 Sep;22(9):1306-1312.(Nature子刊,IF=13.2,一区)
Qin XY, Feng JC, Cao C, Wu HT, Loh YP,Cheng Y*.Association of Peripheral Blood Levels of Brain-Derived Neurotrophic Factor With Autism Spectrum Disorderin Children: A Systematic Review and Meta-analysis.JAMA Pediatr.2016; 170(11):1079-1086.(JAMA子刊,IF =10.25,一区)Comment in:Brain-Derived Neurotrophic Factor in Autism Spectrum Disorder.JAMA Pediatr.2017 May 1;171(5):492-493
Qin XY,Zhang SP, Cao C, Loh YP,Cheng Y*.Aberrations in Peripheral Inflammatory Cytokine Levels in Parkinson Disease: A Systematic Review and Meta-analysis.JAMA Neurol.2016;73(11): 1316-1324.(JAMA子刊,IF =10.03,一区)Editorial:Cytokines as Potential Biomarkers of Parkinson Disease.JAMA Neurol.2016 Nov 1;73(11):1282-1284
Comment in:Circulating Interleukin 6 in Parkinson Disease.JAMA Neurol.2017 May 1;74(5):607-608
Cheng Y,Cawley NX, Yanik T, Murthy SR, Liu C, Kasikci F, Abebe D, Loh YP. A Human Carboxypeptidase E/NF-a1 gene mutation in an Alzheimer’s disease patient leads to Dementia and Depression in mice.Translational Psychiatry(2016)6, e973.(IF=4.7,二区)
Cong L, Cao, C,Cheng, Y*,Qin XY*. Green tea polyphenols attenuated glutamate excitotoxicity via anti-oxidative and anti-apoptotic pathway in the primary cultured cortical neurons.Oxidative Medicine and Cellular Longevity. 2016;2016:2050435.(IF = 4.6,二区)
Zhang Y, Che M, Yuan J, Yu Y, Cao C, Qin XY,Cheng Y*. Aberrations in circulating inflammatory cytokine levels in patients with Down syndrome: a meta-analysis. Oncotarget. 2017 Sep 19;8(48):84489-84496(IF = 5.1,二区).
Cheng Y,LohYP, Birch NP.Neuroserpin Attenuates H2O2-Induced Oxidative Stress in Hippocampal Neurons via AKT and BCL-2 Signaling Pathways.J Mol Neurosci. 2017 Jan;61(1):123-131.
Pan RY, Ma J, Wu HT, Liu QS, Qin XY*,Cheng Y*.Neuroprotective effects of a Coeloglossum viride var. Bracteatum extract in vitro and in vivo.Sci Rep. 2017 Aug 23;7(1):9209.
Hu Y, Cao C, Qin XY, Yu Y, Yuan J, Zhao Y,Cheng Y*.Increased peripheral blood inflammatory cytokine levels in amyotrophic lateral sclerosis: a meta-analysis study.Sci Rep. 2017 Aug 22;7(1):9094.
Thouennon E,Cheng Y,Falahatian V, Cawley NX, Loh YP.Rosiglitazone-activated PPARγ induces neurotrophic factor-α1 transcription contributing to neuroprotection.J Neurochem. 2015 Aug;134(3):463-70.共同一作
Cheng Y,Li Z, Kardami E, Loh YP.Neuroprotective effects of LMW and HMW FGF2 against amyloid beta toxicity in primary cultured hippocampal neurons.Neurosci Lett. 2016 Oct 6;632:109-13.
Cheng Y, Yu LC.Galanin up-regulates the expression of M1 muscarinic acetylcholine receptor via the ERK signaling pathway in the primary cultured prefrontal cortical neurons.Neurosci Lett.2015. 590:161-165.
Liu T.Y,Cheng Y*, Qin XY*, Yu L.C. Pharmacologically inhibiting GluR2 internalization alleviates neuropathic pain.Neuroscience bulletin.2015 Oct;31(5):611-6.