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个人简介

汉族,理学博士(清华大学 --- 北京协和医学院),教授,博士生导师,中央民族大学学术带头人(2015-),中央民族大学高层次优秀人才(2016-),入选中华人民共和国国家民族事务委员会第四批“中青年英才培养计划”(2018)。 曾任 Research Scientist & Postdoctoral Fellow(University of Victoria - Genome BC Proteomics Centre,Canada,2012-2015),Research Scientist(Metabolomics Innovation Centre (TMIC)& Science and Technology Innovation Centre(STIC),Canada,2012-2015); Human Proteome Organization (HUPO)、American Society for Mass Spectrometry (ASMS)、American Chemical Society(ACS)、Canadian National Proteomics Network (CNPN)、Canadian Society for Chemistry (CSC)会员;Molecular & Cellular Proteomics、 Analytical Chemistry、Analytica Chimica Acta、Journal of Mass Spectrometry、Journal of Proteome Research、Proteomics、Journal of Proteomics、Electrophoresis、International Journal of Mass Spectrometry、Analytical and Bioanalytical Chemistry、Journal of the American Society for Mass Spectrometry 、 Rapid Communications in Mass Spectrometry 、 Metabolomics、Methods、RSC Advances、Analyst、Phytochemical Analysis、Behavioural Brain Research、BioTechniques 等国际著名期刊同行评阅人(Peer-Reviewer);Analytical Methods in Chemistry 特邀客座编辑(Guest Editor)。 曾荣获“Young Investigator Award, 6th Annual CNPN Symposium,Canada(2014)”,“北京市优秀毕业生奖(2012,证书编号:证字第 201210023y014 号)”, ACTA Biophysica Sincia杂志“2009 年度优秀论文”奖,北京协和医学院--清华大学一等奖学金(2011、2010)、三等奖学金(2008)、优秀研究生奖(2011、2010、2009)、助研一等奖学金(2010、2009)、助研二等奖学金(2011)、国家生物科学理科基地创新一等奖学金(2006)。

研究领域

质谱成像,蛋白质组学,代谢组学,分析化学

近期论文

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Copper adhesive tape attached to reverse side of non-conductive glass slide to achieve protein MALDI-imaging in FFPE-tissue sections A Caffeic Acid Matrix Improves In Situ Detection and Imaging of Proteins with High Molecular Weight Close to 200,000 Da in Tissues by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Enhanced in-situ detection and imaging of lipids in biological tissues by using 2,3-dicyanohydroquinone as a novel matrix for positive-ion MALDI-MS Imaging 3,4-Dimethoxycinnamic Acid as a Novel Matrix for Enhanced In Situ Detection and Imaging of Low-Molecular-Weight Compounds in Biological Tissues by MALDI-MSI Matrix coating assisted by an electric field (MCAEF) for enhanced tissue imaging by MALDI-MS Spatial Lipidomics of EPSPS and PAT Transgenic and Non-Transgenic Soybean Seeds Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging In Situ Proteomic Analysis of Herbicide-Resistant Soybean and Hybrid Seeds via Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging Wet-Spinning of Continuous Hyaluronic-Based MXene/CNTs Hybrid Fibers for Flexible Supercapacitor Applications Polyacrylamide gel as a new embedding medium for the enhancement of metabolite MALDI imaging Rapid fabrication of coal gangue-based alkali activated foams and application as pH regulators Evaluation of porosity, mechanical and thermal properties of self-ignition coal gangue-based foams via fast microwave foaming A concentration-descending washing strategy with methanol for the enhancement of protein imaging in biological tissues by MALDI-MS Curing kinetics and mechanical properties of an underwater SiO 2 /epoxy adhesive High-temperature steam oxidation behavior of an FeCrAl alloy with controlled addition of Mo In-situ detection and imaging of Areca catechu fruit alkaloids by MALDI-MSI Layer-by-layer macroassembly of inorganic CNTs and MXenes with organic PVA for enhancing the interfacial properties of carbon fiber/epoxy composites Micropropagation system of Anaphalis hancockii Maxim in vitro and exploration of endogenous metabolome differences coursed by plant growth regulators Improving Thermal Insulation Properties of Lightweight Epoxy Resin Matrix Composites with Millimeter-Sized Hollow Glass Microspheres/Epoxy Hollow Spheres Mass Spectrometry Imaging of Lipids in the Scent Glands of Muskrat (Ondatra zibethicus) in Different Reproductive Statuses Synthesis and application of chitosan thiourea derivatives as chiral stationary phases in HPLC Preparation, properties and applications of fly ash-based porous geopolymers: A review Cytology, transcriptomics, and mass spectrometry imaging reveal changes in late-maturation elm (Ulmus pumila) seeds Chemical derivatization: recent advances in mass spectrometry imaging Michler's ethylketone as a novel negative-ion matrix for the enhancement of lipid MALDI tissue imaging High-Temperature Steam Oxidation Behavior of an Fecral Alloy with a Controlled Mo Addition Caffeic acid matrix improves in situ detection and imaging of proteins with high molecular weight close to 200,000 Da in tissues by MALDI-MSI Preparation and microwave absorption of CIP/EP hollow sphere lattice composites UPLC–MS-Based Non-targeted Analysis of Endogenous Metabolite Changes in the Leaves of Scabiosa tschiliensis Grüning Induced by 6-Benzylaminopurine and Kinetin Absolute Quantification of 2‐Hydroxyglutarate on Tissue by MALDI MSI for Rapid and Precise Identification of IDH Mutations in Human Glioma Proteomics: recent advances in the analysis of diabetic kidney disease Preparation and Properties Study of Cr on FeCrAl Cladding Materials Effects of surfactants/stabilizing agents on the microstructure and properties of porous geopolymers by direct foaming Metabolite changes associated with earthworms (Eisenia fetida) graphene exposure revealed by matrix-assisted laser desorption/ionization mass spectrometry imaging Complement Factor H Displays Opposite Expression Patterns Under Two Situations of Methamphetamine Administration: Acute Exposure and Chronic Dependence The curing kinetics and mechanical properties of epoxy resin composites reinforced by PEEK microparticles Simultaneous colorimetric sensing of malachite & leucomalachite green in aquatic products based on novel ionic associate self-visualization HPTLC strips Performance of high-temperature thermosetting polyimide composites modified with thermoplastic polyimide Investigation of the Thermal Conductivity of Resin-Based Lightweight Composites Filled with Hollow Glass Microspheres Integrated transcriptome and miRNA analysis uncovers molecular regulators of aerial stem-to-rhizome transition in the medical herb Gynostemma pentaphyllum Pd/Cu-Catalyzed Cascade C(sp 3 )–H Arylation and Intramolecular C–N Coupling: A One-Pot Synthesis of 3,4-2 H -Quinolinone Skeletons 3,4-Dimethoxycinnamic acid (DMCA) as a novel matrix for enhanced in situ detection and imaging of low-MW compounds in biological tissues by MALDI-MSI Recent advances in matrix‐assisted laser desorption/ionisation mass spectrometry imaging (MALDI‐MSI) for in situ analysis of endogenous molecules in plants Metabolomic insights into the effects of thyroid hormone on Rana [Lithobates] catesbeiana metamorphosis using whole-body Matrix Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging (MALDI-MSI) Mass spectrometry imaging for in situ analysis of endogenous molecules in plants Poplar catkin: A natural biomaterial for highly specific and efficient enrichment of sialoglycopeptides Metabolomic profiling of prostate cancer by matrix assisted laser desorption/ionization-Fourier transform ion cyclotron resonance mass spectrometry imaging using Matrix Coating Assisted by an Electric Field (MCAEF) Generation of regulatory dendritic cells after treatment with paeoniflorin Untargeted saliva metabonomics study of breast cancer based on ultra performance liquid chromatography coupled to mass spectrometry with HILIC and RPLC separations Ion-Beam-Directed Self-Ordering of Ga Nanodroplets on GaAs Surfaces The use of matrix coating assisted by an electric field (MCAEF) to enhance mass spectrometric imaging of human prostate cancer biomarkers The Effect of Traditional Chinese Formula Danchaiheji on the Differentiation of Regulatory Dendritic Cells Thermal conductivity and compressive properties of hollow glass microsphere filled epoxy-matrix composites Investigation of salivary free amino acid profile for early diagnosis of breast cancer with ultra performance liquid chromatography-mass spectrometry GRP75 Involves in Retinal Ganglion Cell Apoptosis After Rat Optic Nerve Crush Site-controlled fabrication of Ga nanodroplets by focused ion beam Current Controversies in Neoadjuvant Chemoradiation of Rectal Cancer Comprehensive Imaging of Porcine Adrenal Gland Lipids by MALDI-FTMS Using Quercetin as a Matrix Elevated Serum Levels of Circulating Immunoinflammation-Related Protein Complexes Are Associated with Cancer Microbial Floral Dynamics of Chinese Traditional Soybean Paste (Doujiang) and Commercial Soybean Paste A Special Issue on Nanomaterials Physics Change in IgG 1 Fc N -linked glycosylation in human lung cancer: Age- and sex-related diagnostic potential Hydroxyflavones as a New Family of Matrices for MALDI Tissue Imaging Dephosphorylation of intact glycoprotein to greatly improve digestion efficiency coupled with matrix-assisted laser desorption/ionization-Fourier transform ion cyclotron resonance mass spectrometric analysis Activation of type 2 cannabinoid receptors (CB2R) promotes fatty acid oxidation through the SIRT1/PGC-1α pathway Improved efficiency of InAs/GaAs quantum dots solar cells by Si-doping Improved efficiency of InAs/GaAs quantum dots solar cells by Si-doping Lipid profiling for early diagnosis and progression of colorectal cancer using direct-infusion electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry Display of heterologous protein on the surface of Lactobacillus plantarum by using the CspI anchor protein Probing gender-specific lipid metabolites and diagnostic biomarkers for lung cancer using Fourier transform ion cyclotron resonance mass spectrometry Broad-spectrum Four-dimensional Orthogonal Electrophoresis: A Novel Comprehensively Feasible System for Protein Complexomics Investigation Human IgG Fc-glycosylation profiling reveals associations with age, sex, female sex hormones and thyroid cancer Proteomics-based Characterization of Protein Complexes from Human Pancreatic Cancer Cell Line Separation and Identification of HSP-Associated Protein Complexes from Pancreatic Cancer Cell Lines Using 2D CN/SDS-PAGE Coupled with Mass Spectrometry Four-Dimensional Orthogonal Electrophoresis System for Screening Protein Complexes and Protein-Protein Interactions Combined with Mass Spectrometry In vitro methylation by methanol: Proteomic screening and prevalence investigation Cross-linking and mass spectrometry for investigation of protein complex structures and protein-protein interactions

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