陈剑清 - 浙江理工大学 - 生命科学与医药学院

个人简介

1. 2004年毕业于浙江工商大学生物工程专业，获工学学士学位； 2. 2007年毕业于浙江理工大学生物化学与分子生物学专业，获理学硕士学位； 3. 2007年4月至今留校任教，2009年4月任生化所助理研究员； 4. 2009年-2011年，参与禽流感疫苗的研制与工艺优化，完成临床申报并获得临床申报受理； 5. 2011年至今，负责蛹虫草系列产品的研究与开发。

研究领域

蛹虫草抗肿瘤组分的研究与开发

近期论文

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1. 陈剑清, 张耀洲*. EF手图像超家族成员——肌钙蛋白C的研究进展. 生物工程学报, 2007, 23: 375-380. 2. 叶曼, 黄宏杰, 何靖, 陈剑清, 张耀洲*. 利用GST融合多肽制备人源膜受体多抗的研究. 浙江理工大学学报, 2010, 27(4): 636-640. 3. 严巧灵, 陈剑清, 王丹, 叶曼, 吴祥甫, 张耀洲*. 家蚕肌钙蛋白CⅢ基因的原核表达及其抗体的制备. 农业生物技术学报, 2010, 18(6): 1156-1162. 4. Jianqing Chen, Jian Chen, Qijing Gai, Zhengbing Lv, Dan Wang, Zuoming Nie, Jiang Wang, Xuedong Wang, Xiangfu Wu, Yaozhou Zhang. Molecular Characterization and Immunohistochemical Localization of a Novel Troponin C During Silkworm Development. Cell & Tissue Research, 2008, 331: 725-738. 5. Ping-an He, Zuoming Nie, Jianqing Chen, Jian Chen, Zhengbing Lv, Qing Sheng, Songping Zhou, Xiaolian Gao, Lingyin Kong, Xiangfu Wu, Yongfeng Jin and Yaozhou Zhang. Identification and characteristics of microRNAs from Bombyx mori. BMC Genomics. 2008, 9: 248. 6. Yaozhou Zhang, Zhengbing Lv, Jian Chen, Qin Chen, Yanping Quan, Lingyin Kong, Haihua Zhang, Si Li, Qingliang Zheng, Jianqing Chen, Zuoming Nie, Jiang Wang, Yongfeng Jin, Xiangfu Wu. A Novel Method for Isolation of Membrane Proteins: A Baculovirus Surface Display System. Proteomics, 2008, 8 (20): 4178-4185. 7. Zhang Y, Xia Q, Xu J, Chen J, Nie Z, Wang D, Zhang W, Chen J, Zheng Q, Chen Q, Kong L, Ren X, Wang J, Lv Z, Yu W, Jiang C, Liu L, Sheng Q, Jin Y, Wu X. Aligning the proteome and genome of the silkworm, Bombyx mori. Funct Integr Genomics. 2009, 9(4): 447-454. 8. Shen Y, Zhang T, Chen J, Lv Z, Chen J, Wang D, Nie Z, He P, Wang J, Zheng Q, Sheng Q, Wu X, Zhang Y. Molecular Characterization and Tissue Localization of an F-Box Only Protein from Silkworm, Bombyx mori. Comp Funct Genomics. 2009.06. Online doi: 10.1155/2009/416040. 9. Zeng F, Xie H, Nie Z, Chen J, Lv Z, Chen J, Wang D, Liu L, Yu W, Sheng Q, Wu X, Zhang Y. Characterization of the Gene BmEm4, a Homologue of Drosophila E(spl)m4, from the Silkworm, Bombyx mori. Comp Funct Genomics. 2009.10. Online doi: 10.1155/2009/947490. 10. Hanglian Lan, Zuoming Nie, Yue Liu, Zhengbing Lv, Yingshuo Liu, Yanping Quan, Jianqing Chen, Qingliang Zhen, Qin Chen, Dan Wang, Qing Sheng, Wei Yu, Jian Chen, Xiangfu Wu, Yaozhou Zhang. In vivo Bioassay of Recombinant human growth hormone synthesized in B. mori pupae. J BIOMED BIOTECHNOL. 2010; 2010: 306462. 11. Jianqing Chen, Qijing Gai, Zhengbing Lv, Jian Chen, Zuoming Nie, Xiangfu Wu, Yaozhou Zhang. All-Trans Retinoic Acid Affects Subcellular Localization of a Novel BmNIF3l Protein: Functional Deduce and Tissue Distribution of NIF3l Gene from Silkworm (Bombyx mori). ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY, 2010, 74(4): 217–231. 12. Liu Y, Chen Y, Chen J, Zhang W, Sheng Q, Chen J, Yu W, Nie Z, Zhang Y, Wu W, Wang L, Indran IR, Li J, Qian L, Lv Z. A Shark Liver Gene-Derived Active Peptide Expressed in the Silkworm, Bombyx mori: Preliminary Studies for Oral Administration of the Recombinant Protein. Mar Drugs. 2013, 11(5):1492-505. doi: 10.3390/md11051492.