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个人简介

1994年获兰州大学理学学士 1997年获兰州大学理学硕士 1997-1998年,中国辐射防护研究院工作 2001年获北京大学理学博士学位

研究领域

药物合成以及核素、荧光标记,用于心肌、肿瘤以及乏氧组织的显像 开展核燃料循环化学的基础性和前瞻性研究,尤其是发展先进的核燃料后处理方法

近期论文

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Xin Sun, Taiwei Chu*, Xiangyun Wang(2010). Preliminary studies of 99mTc-BnAO and its analogues: synthesis, radiolabeling and in vitro cell uptake. Nucl. Med. Biol. 37(2): 117-123. Xin Sun, Taiwei Chu*, Xiangyun Wang (2010). Tumor angiogenesis imaging agent: biodistribution of 131I-YG5 and 131I-Boc-YG5. Nuclear Science and Techniques 21(5): 257-261. Taiwei Chu*, Zejun Li, Xiangyun Wang (2009). Synthesis and biological evaluation of radioiodinated 2NUBTA as a cerebral ischemia marker, Bioorgan. Med. Chem. Lett. 19(3): 658-661. Taiwei Chu, Hong Xu, Zhi Yang, Xiangyun Wang (2009). Synthesis and in vitro evaluation of three 99mTc-labeled hydroxamamide-based ligands as markers for hypoxic cells, Appl. Radiat. Isot. 67(4): 590-593. Liyan Sun, Taiwei Chu*, Yi Wang, Xiangyun Wang(2007). Radiolabeling and biodistribution of a nasopharyngeal carcinoma-targeting peptide identified by in vivo phage display,Acta Biochimica et Biophysica Sinica,39(8):624-632。 Yu Zhang, Taiwei Chu*, Xuguang Gao, Xinqi Liu, Zhi Yang, Zhenquan Guo, Xiangyun Wang ( 2006 ) . Synthesis and preliminary biological evaluation of the 99m Tc labeled nitrobenzoimidazole and nitrotriazole as tumor hypoxia markers. Bioorgan. Med. Chem. Lett. , 16: 1831-1833. Xin Sun, Taiwei Chu*, Xinqi Liu, Xiangyun Wang (2006). t-Butyloxycarbonyl: an ordinary but promising group for protecting peptides from deiodination. Appl. Radiat. Isot., 64(6): 645-650. SUN Li-Yan, CHU Tai-Wei*, WANG Xiang-Yun(2006). Radiolabeling of filamentous phage peptide library with 99mTc and its biodistribution in normal mice. Progress in Biochemistry and Biophysics,33(12):1200-1206. Zejun Li, Taiwei Chu*, Xinqi Liu, Xiangyun Wang (2005). Synthesis and in vitro and in vivo evaluation of the radioiodinated nitroimidazole analogues as tumor hypoxia-imaging agents. Nucl. Med. Biol. 32(3): 225-231 . Hong Xu, Taiwei Chu*, Xiangyun Wang, Xinqi Liu (2005). Facile synthesis of bis(hydroxamamide)-based tetradentate ligands for 99mTc-radiopharmaceuticals. Appl. Radiat. Isot., 62(6): 919-922. Zejun Li, Yu Wei, Taiwei Chu*, Xiangyun Wang, Xinqi Liu, Yi Wang, Shaowen Hu (2005). Radioiodination, biodistribution and pharmacokinetics of berberine in mice. J. Radioanal. Nucl. Chem. 265(3): 355-359. Taiwei Chu, Shaowen Hu, Bing Wei, Yi Wang, Xinqi Liu, Xiangyun Wang (2004), Synthesis and Biological Results of a Technetium -99m -labeled 4-Nitroimidazole for Imaging Tumor Hypoxia. Bioorgan. Med. Chem. Lett., 14(3): 747-749. Taiwei Chu, Rujun Li, Shaowen Hu, Xinqi Liu, Xiangyun Wang (2004), Preparation and Biodistribution of Technetium -99m -labeled 1-(2-Nitroimidazole-1-yl) -propanhydroxyiminoamide (N2IPA) as a Tumor Hypoxia Marker, Nucl. Med. Biol . 31(2): 199-203. Taiwei Chu, Rujun Li, Shaowen Hu, Yi Wang, Xinqi Liu, Xiangyun Wang. Synthesis and biodistribution of the 99mTc nitrido complex with 2-(4-nitro-1H-imidazolyl)ethyl dithiocarbamate (NIET). J. Radioanal. Nucl. Chem. ,2004, 261(1): 199-202. Taiwei Chu, Yu Zhang, Xinqi Liu, Yi Wang, Shaowen Hu, Xiangyun Wang (2004). Synthesis and biodistribution of 99mTc-carbonyltechnetium-labeled fatty acids. Appl. Radiat. Isot. 60(6): 845-850.

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