李子臣 - 北京大学 - 化学与分子工程学院

个人简介

1987.7 在山东大学化学系获理学学士学位 1990.8在中科院化学研究所获硕士学位 1990.9考入北京大学攻读博士学位，其中1993.8-1994.7在日本早稻田大学联合培养一年，1995.1获北京大学博士学位 1995.1-1996.12在北京大学化学学院从事博士后研究，其中1996.3-1996.5，1996.7-1996.12，作为日本学术振兴会特别研究员赴早稻田大学合作研究 1997.1起在北京大学化学学院工作，任讲师；1997.8晋升为副教授；2002.8晋升为教授。

研究领域

高分子合成化学；聚合反应新方法；生物基可降解回收高分子材料；刺激响应性高分子及其生物医学应用

近期论文

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Meng, X.-B.; Zhou, T.; Yang, C.; Cheng, X.-Y.; Wu, X.-T.; Shi, C.; Du, F.-S.; Li, Z.-C., Thermally Stable and Chemically Recyclable Poly(ketal-ester)s Regulated by Floor Temperature. J. Am. Chem. Soc., 2024, https://doi.org/10.1021/jacs.4c03523. Wu, X.-T.; Yang, C.; Xi, J.-S.; Shi, C.; Du, F.-S.; Li, Z.-C., Enabling Closed-Loop Circularity of “Non-Polymerizable” α, β-Conjugated Lactone Towards High-Performance Polyester with the Assistance of Cyclopentadiene. Angew. Chem. Int. Ed., 2024, 63 (22), e202404179. Zhou, T.; Guo, Y.-T.; Yang, C.; Meng, X.-B.; Du, F.-S.; Li, Z.-C., High-Tg PLA Copolymers via Base-catalyzed Transesterification of PLA with 2,5,7-Trioxabicyclo 2.2.2 octan-6-one. Polym. Chem., 2024, 15 (3), 156-165. Cheng, X.-Y.; Du, F.-S.; Li, Z.-C., Synthesis of Precision Poly(1,3-Bicyclo 1.1.1 Pentane alkylene)s via Acyclic Diene Metathesis Polymerization. J. Polym. Sci., 2023, 61 (6), 472-481. Fan, W.; Xiang, J.; Wei, Q.; Tang, Y.; Piao, Y.; Shao, S.; Zhou, Z.; Tang, J.; Li, Z.-C.; Shen, Y., Role of Micelle Size in Cell Transcytosis-Based Tumor Extravasation, Infiltration, and Treatment Efficacy. Nano Lett., 2023, 23 (9), 3904-3912. Fan, W.; Wei, Q.; Xiang, J.; Tang, Y.; Zhou, Q.; Geng, Y.; Liu, Y.; Sun, R.; Xu, L.; Wang, G.; Piao, Y.; Shao, S.; Zhou, Z.; Tang, J.; Xie, T.; Li, Z.; Shen, Y., Mucus Penetrating and Cell-Binding Polyzwitterionic Micelles as Potent Oral Nanomedicine for Cancer Drug Delivery. Adv. Mater., 2022, 34 (16), 2109189. Yu, L.; Zhou, Q.; Gao, Y.; Fu, Z.; Xiao, Y.; Li, Z.-C.; Wang, J., Synthesis of Polyallenoates through Copper-Mediated Cross-coupling of Dialkynes and Bis-α-diazoesters. Chem. Commun., 2022, 58 (24), 3909-3912. Guo, Y.-T.; Shi, C.; Du, T.-Y.; Cheng, X.-Y.; Du, F.-S.; Li, Z.-C., Closed-Loop Recyclable Aliphatic Poly(ester-amide)s with Tunable Mechanical Properties. Macromolecules 2022, 55 (10), 4000-4010. Guo, Y.-T.; Xiong, W.; Shi, C.; Du, F.-S.; Li, Z.-C., Facile Synthesis of Eight-Membered Cyclic(ester-amide)s and Their Organocatalytic Ring-Opening Polymerizations. Polym. Chem., 2022, 13 (31), 4490-4501. Li, Z.; Qian, Y.; Du, F.-S.; Li, Z.-C., Synthesis and Post-Functionalization of Poly(conjugated ester)s Based on 3-Methylene-1,5-dioxepan-2-one. Biomacromolecules 2022, 23 (12), 5213-5224. Lei, J.-X.; Wang, Q.-Y.; Du, F.-S.; Li, Z.-C., Dynamic Ring-chain Equilibrium of Nucleophilic Thiol-yne "Click" Polyaddition for Recyclable Poly(dithioacetal)s. Chin. J. Polym. Sci., 2021, 39 (9), 1146-1154. Li, L.-G.; Wang, Q.-Y.; Zheng, Q.-Y.; Du, F.-S.; Li, Z.-C., Tough and Thermally Recyclable Semiaromatic Polyesters by Ring-Opening Polymerization of Benzo-thia-caprolactones. Macromolecules 2021, 54 (14), 6745-6752. Yang, Y.; Du, F.-S.; Li, Z.-C., Thermally Healable and Reprocessable Polymethacrylate Networks Based on Diol-Mediated Metathesis of 6-Membered Boronic Esters. Polym. Chem., 2020, 11 (11), 1860-1870. Yang, Y.; Du, F.-S.; Li, Z.-C., Highly Stretchable, Self-Healable, and Adhesive Polyurethane Elastomers Based on Boronic Ester Bonds. ACS Applied Polym. Mater., 2020, 2 (12), 5630-5640. Shi, C.-X.; Guo, Y.-T.; Wu, Y.-H.; Li, Z.-Y.; Wang, Y.-Z.; Du, F.-S.; Li, Z.-C., Synthesis and Controlled Organobase-Catalyzed Ring-Opening Polymerization of Morpholine-2,5-Dione Derivatives and Monomer Recovery by Acid-Catalyzed Degradation of the Polymers. Macromolecules 2019, 52 (11), 4260-4269. Yu, L.; Ke, H.-L.; Du, F.-S.; Li, Z.-C., Redox-Responsive Fluorescent Polycarbonates Based on Selenide for Chemotherapy of Triple-Negative Breast Cancer. Biomacromolecules 2019, 20 (7), 2809-2820. Su, S.; Du, F.-S.; Li, Z.-C., Facile Synthesis of a Degradable Poly(ethylene glycol) Platform with Tunable Acid Sensitivity at Physiologically Relevant pH. Macromolecules 2018, 51 (17), 6571-6579. Su, S.; Wang, Y.-Y.; Du, F.-S.; Lu, H.; Li, Z.-C., Dynamic Covalent Bond-Assisted Programmed and Traceless Protein Release: High Loading Nanogel for Systemic and Cytosolic Delivery. Adv. Funct. Mater., 2018, 28 (48), 1805287. Zhang, J.; Wu, Y.-H.; Wang, J.-C.; Du, F.-S.; Li, Z.-C., Functional Poly(ester-amide)s with Tertiary Ester Linkages via the Passerini Multicomponent Polymerization of a Dicarboxylic Acid and a Diisocyanide with Different Electron-Deficient Ketones. Macromolecules 2018, 51 (15), 5842-5851.