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Jiao Hou, Youmei Peng, Bingjie Liu, Qianqian Zhang, Jian-Hua Wang, Wenquan Yu,* Junbiao Chang.* "4'-Ethynyl-2'-deoxy-2'-β-fluoro-2-fluoroadenosine: A Highly Potent and Orally Available Clinical Candidate for the Treatment of HIV-1 Infection." Journal of Medicinal Chemistry, 2023, 66 (16), 11282-11293.
Manman Wang, Xiaofei Yi, Wenjun Ye, Qinhao Shi, Wenquan Yu,* Junbiao Chang.* "Iodine-Mediated α-C–H Amination of Carbonyl Compounds via Nitrogen-Directed Oxidative Umpolung." Journal of Organic Chemistry, 2023, 88 (13), 8751-8760.
Manman Wang, Wenjun Ye, Nannan Sun, Wenquan Yu,* Junbiao Chang.* "Synthesis of Quinazolinone-Fused Tetrahydroisoquinolines and Related Polycyclic Scaffolds by Iodine-Mediated sp3 C–H Amination." Journal of Organic Chemistry, 2023, 88 (2), 1061-1074.
Xiaofei Yi, Zongxiang Zhao, Manman Wang, Wenquan Yu,* Junbiao Chang.* "Synthesis of 1,2-Fused/Disubstituted Benzimidazoles and Benzimidazolium Salts by I2-Mediated sp3 C–H Amination." Organic Letters, 2022, 24 (47), 8703-8708.
Yingchao Fang, Manman Wang, Wei Hao, Yinggao Meng, Wenquan Yu,* Junbiao Chang.* "Transition-Metal-Free N-Functionalization of Benzimidazoles and Related Azaheterocycles with α-Acyloxy Sulfides." Advanced Synthesis & Catalysis, 2022, 364 (17), 2922-2925.
Qianqian Zhang,# Youmei Peng,# Jiao Hou, Yanhong Chen, Bingjie Liu, Pinghu Zhang, Wenquan Yu,* Junbiao Chang.* "An O-Benzyl Phosphonamidate Prodrug of Tenofovir for the Treatment of Hepatitis B Virus Infection." Journal of Medicinal Chemistry, 2022, 65 (13), 9493-9505.
Wei Hao, Kailu Li, Chenyang Ye, Wenquan Yu,* Junbiao Chang.* "Iodine-Mediated C=C Double Bond Cleavage toward Pyrido[2,1-b]quinazolinones." Organic Letters, 2022, 24 (17), 3286-3290.
Lanlan Wei,# Manman Wang,# Yifei Zhao, Yingchao Fang, Zongxiang Zhao, Biao Xia, Wenquan Yu,* Junbiao Chang.* "Synthesis of 1,4-Dihydropyridines and Related Heterocycles by Iodine-Mediated Annulation Reactions of N-Cyclopropyl Enamines." Organic Letters, 2021, 23 (24), 9625-9630.
Zhengyan Huang, Qianqian Zhang, Xiaofei Yi, Zongxiang Zhao, Wenquan Yu,* Junbiao Chang.* "Synthesis of 2-Imino-1,3,4-Selenadiazoles via Tributylphosphine-Mediated Annulation of N-Aroyldiazenes with Isoselenocyanates." Advanced Synthesis & Catalysis, 2021, 363 (21), 4894-4898.
Wenjun Chen, Yangxu Du, Manman Wang, Yingchao Fang, Wenquan Yu,* Junbiao Chang.* "Synthesis of Benzo[4,5]imidazo[1,2-a]quinoxalines by I2-Mediated sp3 C−H Amination." Organic Chemistry Frontiers, 2020, 7 (22), 3705-3708. DOI: 10.1039/d0qo01101k
Zhengyan Huang, Qianqian Zhang, Qiongli Zhao, Wenquan Yu,* Junbiao Chang.* "Synthesis of 2-Imino-1,3,4-thiadiazoles from Hydrazides and Isothiocyanates via Sequential Oxidation and P(NMe2)3-Mediated Annulation Reactions." Organic Letters, 2020, 22 (11), 4378-4382.
Shuangshuang Zhang, Qiongli Zhao, Yifei Zhao, Wenquan Yu,* Junbiao Chang.* "Synthesis of 2-Amino Substituted Oxazoles from α-Amino Ketones and Isothiocyanates via Sequential Addition and I2-Mediated Desulfurative Cyclization." Advanced Synthesis & Catalysis, 2020, 362 (10), 1993-1997.
Li Sun,# Youmei Peng,# Wenquan Yu,# (#co-first authors) Yan Zhang, Lan Liang, Chuanjun Song, Jiao Hou, Yan Qiao, Qingduan Wang, Jingyu Chen, Mengli Wu, Dongwei Zhang, Ertong Li, Zhifu Han, Qingxia Zhao, Xia Jin, Bailing Zhang, Zhiwei Huang, Jijie Chai,* Jian-Hua Wang,* Junbiao Chang.* "Mechanistic Insight into Antiretroviral Potency of 2'-Deoxy-2'-β-fluoro-4'-azidocytidine (FNC) with a Long-Lasting Effect on HIV-1 Prevention." Journal of Medicinal Chemistry, 2020, 63 (15), 8554-8566.
Benyao Fang, Jiao Hou, Jinyue Tian, Wenquan Yu,* Junbiao Chang.* "Synthesis of Phenanthridines by I2-Mediated sp3 C−H Amination." Organic & Biomolecular Chemistry, 2020, 18 (17), 3312-3323.
Biao Xia, Wenjun Chen, Qiongli Zhao, Wenquan Yu,* Junbiao Chang.* "Synthesis of Functionalized Imidazolium Salts via Iodine-Mediated Annulations of Enamines." Organic Letters, 2019, 21 (8), 2583-2587.
Linning Ren, Manman Wang, Benyao Fang, Wenquan Yu,* Junbiao Chang.* "Iodine-Mediated Oxidative N−N Coupling of Secondary Amines to Hydrazines." Organic & Biomolecular Chemistry, 2019, 17 (13), 3446-3450.
Qiongli Zhao, Linning Ren, Jiao Hou, Wenquan Yu,* Junbiao Chang.* "Annulation Reactions of In-situ Generated N-(Het)aroyldiazenes with Isothiocyanates Leading to 2-Imino-1,3,4-oxadiazolines." Organic Letters, 2019, 21 (1), 210-213.
Manman Wang, Jiao Hou, Wenquan Yu,* Junbiao Chang.* "Synthesis of 2H-Azirines via Iodine-Mediated Oxidative Cyclization of Enamines." Journal of Organic Chemistry, 2018, 83 (24), 14954-14961.
Ertong Li, Manman Wang, Zhen Wang, Wenquan Yu,* Junbiao Chang.* "NBS-Mediated Practical Cyclization of N-Acyl Amidines to 1,2,4-Oxadiazoles via Oxidative N−O Bond Formation." Tetrahedron, 2018, 74 (35), 4613-4618.
Zhiyuan Hu, Jiao Hou, Jie Liu, Wenquan Yu,* Junbiao Chang.* "Synthesis of Imidazo[1,5-a]pyridines via I2-Mediated sp3 C−H Amination." Organic & Biomolecular Chemistry, 2018, 16 (31), 5653-5660.
Yinggao Meng, Bingnan Wang, Linning Ren, Qiongli Zhao, Wenquan Yu,* Junbiao Chang.* "I2-Mediated Transition-Metal-Free Aromatic C−H Amination for the Synthesis of Benzimidazol-2-ones and Related Heterocycles." New Journal of Chemistry, 2018, 42 (16), 13790-13796.
Shufeng Jiao, Zhen Wang, Qiongli Zhao, Wenquan Yu,* and Junbiao Chang.* "Synthesis of Fused 3-Amino-1,2,4-triazoles via Sequential Addition of Aryl Hydrazines to Isothiocyanates and I2-Mediated Cyclodesulfurization." Tetrahedron, 2018, 74 (24), 3069-3073.
Zhen Wang, Qiongli Zhao, Jiao Hou, Wenquan Yu,* and Junbiao Chang.* "Iodine-Mediated Direct Synthesis of Multifunctional 2-Aminobenzimidazoles from N-Substituted o-Diaminoarenes and Isothiocyanates." Tetrahedron, 2018, 74 (19), 2324-2329.
Zhigang Li, Zechun Wang, Ning Wang, Xinxin Han, Wenquan Yu,* Ruiyong Wang,* Junbiao Chang.* "Identification of the Binding between Three Fluoronucleoside Analogues and Fat Mass and Obesity-Associated Protein by Isothermal Titration Calorimetry and Spectroscopic Techniques." Journal of Pharmaceutical and Biomedical Analysis, 2018, 149, 290-295.
Manman Wang, Yinggao Meng, Wei Wei, Jie Wu, Wenquan Yu,* Junbiao Chang.* "Iodine/Copper(I)-Catalyzed Direct Annulation of N-Benzimidazolyl Amidines with Aldehydes for the Synthesis of Ortho-Fused 1,3,5-Triazines." Advanced Synthesis & Catalysis, 2018, 360 (1), 86-92.
Ertong Li,# Yafeng Wang,# Wenquan Yu,# (#co-first authors) Zhigang Lv, Youmei Peng, Bingjie Liu, Shiliang Li, Wenzhe Ho, Qingduan Wang, Honglin Li, Junbiao Chang.* "Synthesis and Biological Evaluation of a Novel β-D-2'-Deoxy-2'-α-fluoro-2'-β-C-(fluoromethyl)uridine Phosphoramidate Prodrug for the Treatment of Hepatitis C Virus Infection." European Journal of Medicinal Chemistry, 2018, 143, 107-113.
Wei Wei, Zhen Wang, Xikang Yang, Wenquan Yu,* and Junbiao Chang.* "Divergent Synthesis of 1H-Indazoles and 1H-Pyrazoles from Hydrazones via Iodine-Mediated Intramolecular Aryl and sp3 C−H Amination." Advanced Synthesis & Catalysis, 2017, 359 (19), 3378-3387.
Wenquan Yu, Ertong Li, Zhigang Lv, Ke Liu, Xiaohe Guo, Yuan Liu, Junbiao Chang.* "Synthesis and Anti-HCV Activity of a Novel 2',3'-Dideoxy-2'-α-fluoro-2'-β-C-methyl Guanosine Phosphoramidate Prodrug." ACS Medicinal Chemistry Letters, 2017, 8 (6), 682-684.
Bingnan Wang, Yinggao Meng, Yiming Zhou, Linning Ren, Jie Wu, Wenquan Yu,* and Junbiao Chang.* "Synthesis of 5-Amino and 3,5-Diamino Substituted 1,2,4-Thiadiazoles by I2-Mediated Oxidative N−S Bond Formation." Journal of Organic Chemistry, 2017, 82 (11), 5898-5903.
Zhiyuan Hu, Ting Zhao, Manman Wang, Jie Wu, Wenquan Yu,* Junbiao Chang.* "I2-Mediated Intramolecular C–H Amidation for the Synthesis of N-Substituted Benzimidazoles." Journal of Organic Chemistry, 2017, 82 (6), 3152-3158.
Zhigang Lv, Bingnan Wang, Zhiyuan Hu, Yiming Zhou, Wenquan Yu,* Junbiao Chang.* "Synthesis of Quinazolines from N,N'-Disubstituted Amidines via I2/KI-Mediated Oxidative C−C Bond Formation." Journal of Organic Chemistry, 2016, 81 (20), 9924-9930.
Jing Liu, Wei Wei, Ting Zhao, Xuanyu Liu, Jie Wu, Wenquan Yu,* Junbiao Chang.* "Iodine/Copper Iodide-Mediated C‒H Functionalization: Synthesis of Imidazo[1,2-a]pyridines and Indoles from N-Aryl Enamines." Journal of Organic Chemistry, 2016, 81 (19), 9326-9336.
Zhigang Lv, Jing Liu, Wei Wei, Jie Wu, Wenquan Yu,* and Junbiao Chang.* "Iodine-Mediated Aryl C–H Amination for the Synthesis of Benzimidazoles and Pyrido[1,2-a]benzimidazoles." Advanced Synthesis & Catalysis, 2016, 358 (17), 2759-2766.
Ertong Li, Zhiyuan Hu, Lina Song, Wenquan Yu,* and Junbiao Chang.* "Synthesis of 1,2,4-Triazolo[4,3-a]pyridines and Related Heterocycles via Sequential Condensation and I2-Mediated Oxidative Cyclization." Chemistry-A European Journal, 2016, 22 (31), 11022-11027.
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