个人简介

Prof. Lin completed his B.S. and M.S. in physical chemistry at National Taiwan University under the supervision of Prof. Lian-Pin Hwang, where they developed new mathematical methods for NMR diffusion study and spectral estimation. He pursued his PhD study with Prof. Alex Pines at University of California at Berkeley on spin dynamics in dipole-coupled many-spin systems in solid-state NMR. They generated new formulation and insights into the effects of quantum decoherence, bath fluctuations, and reaction fields on spin dynamics in quantum dissipative systems based on a spin-boson Hamiltonian. He carried out his postdoctoral research with Prof. Warren in the Department of Chemistry, Princeton University, on nonlinear spin dynamics in solution NMR. They developed the theory and applications of intermolecular quantum coherences and discovered the existence of chaotic spin dynamics in routine experiments. Prof. Lin also holds a degree in Theology from China Evangelical Seminary.

研究领域

Biophysics/Structural Biology/Physical/Analytical

The research theme of Prof. Lin's group is "channeling progress in fundamental spin physics and engineering into significant improvements in magnetic resonance spectroscopy and imaging with valuable applications in the chemical, biological and medical sciences, such as molecular imaging, early tumor/lesion detection, cellular imaging, and nano-medicine." His group encompasses a broad and balanced approach aimed at developing a solid theoretical understanding of new spin phenomena, sound methodology for improving sensitivity and contrast, and innovative applications to solve important biomedical challenges. Specifically, he and his group members currently focus on the following projects in theory, methodology, and applications. (I) Theory: Quantum Theory for Dynamical Instability in Spin Hamiltonians; (II) Theory: Nonlinear Spin Engineering with Multiple Feedback-Field Pulses; (III) Methodology: Feedback-Enhanced MR for Contrast and Sensitivity Enhancement

近期论文

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Y.-Y. Lin, S. Y. Huang Method and System for the Amplification of Nuclear Magnetic Resonance Imaging, , ; PCT/US07/61483. S. Y. Huang, S. S. Yang, Y.-Y. Lin Sensitivity of Feedback-Enhanced MRI Contrast to Macroscopic and Microscopic Field Variations, Magn. Reson. Med., 2007; in press. J. D. Walls, S. Y. Huang, Y.-Y. Lin Spin Amplification in Solution Magnetic Resonance Using Radiation Damping, J. Chem. Phys., 2007; (127): 054507. S. Y. Huang, A. Chung, Y.-Y. Lin Visualizing Feedback-Enhanced Contrast in Magnetic Resonance Imaging, Concepts Magn. Reson. A , 2007; (in press): . J. D. Walls, Y.-Y. Lin Constants of Motion in NMR Spectroscopy, Solid State Nucl. Magn. Reson., 2006; (29): 153???160. S. Datta, S. Y. Huang, Y.-Y. Lin Contrast Enhancement by Feedback Fields in Magnetic Resonance Imaging, J. Phys. Chem. B, 2006; (110): 22071-22078. S. Y. Huang, J. K. Furuyama, Y.-Y. Lin Designing Feedback-Based Contrast Enhancement for In Vivo Imaging, Magn. Reson. Mater. Phys. , 2006; (19): 333-346. J. D. Walls, S. Y. Huang, Y.-Y. Lin , ???,??? J. Excitation of Magnetization Using a Modulated Radiation Damping Field, Phys. Chem. B, 2006; (110): 19985-19989. S. Y. Huang, S. M. Wolahan, G. W. Mathern, D. J. Chute, M. Akhtari, S. T. Nguyen, M. N. Huynh, N. Salamon, Y.-Y. Lin Improving MRI Differentiation of Gray and White Matter in Epileptogenic Lesions Based on Nonlinear Feedback, Magn. Reson. Med., 2006; (56): 776-786. S. Datta, S. Y. Huang, Y.-Y. Lin The Transient Dynamics Leading to Spin Turbulence in High-Field Solution Magnetic Resonance: A Numerical Study, J. Chem. Phys., 2006; (124): 154501.