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个人简介

教育背景 2011.9-2016.6 天津医科大学 基础医学研究中心 医学博士学位 2007.9-2011.6 天津农学院 工学学士学位 工作经历 2016.7- 天津医科大学 医学检验学院 临床生物化学教研室 讲师 荣誉奖励 2016年 Travel Award of 2016 Annual Meeting of the Oligonucleotide Therapeutics Society, Montreal, CA.

研究领域

基因治疗

近期论文

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1.Han G, Gu B, Cao L, Gao X, Wang Q, Seow Y, Zhang N, Matthew J*, Yin H*. Hexose enhances oligonucleotides delivery and exon skipping in dystrophin-deficient mdx mice[J]. Nat Commun, 2016,7:10981. 2.Cao L#,Han G#, Gu B, Lin C, Gao X, Moulton H, Seow Y, Yin H*. Fructose promotes uptake and activity of oligonucleotides with different chemistries in a context-dependent manner in mdx mice [J]. MolTher Nucleic Acids, 2016,5:.e329 3.Cao L, Han G, Gu B, Yin H, Wild-type mouse models to screen antisense oligonucleotides for exon-skipping efficacy in Duchenne muscular dystrophy(2014).PLoS One. 9(11), Nov 3 4.Gao X, Zhao J, Han G, Zhang Y, Dong X, Cao L, Wang Q, Moulton H, Yin H*. Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice[J]. MolTher, 2014,22(7):1333-1341. 5.Wang Q, Han G, Ye J, Gao X,Niu H, Zhao J, Chai Y, Li N, Yin H*. Characterization of the polycystic kidney disease 2 gene promoter[J]. Genomics, 2014,104(6 Pt B):512-519. 6.Gao X, Shen X, Dong X, Ran N, Han G, Cao L,Gu B, Yin H*. Peptide Nucleic Acid PromotesSystemic Dystrophin Expression and Functional Rescue in Dystrophin-deficient mdx Mice[J].MolTher Nucleic Acids, 2015,4:e255. 7.Yang L, Niu H, Gao X, Wang Q, Han G, Cao L, Cai C, Weiler J, Yin H*, Effective exonskipping and dystrophin restoration by 2'-o-methoxyethyl antisense oligonucleotide indystrophin-deficient mice(2013) PLoS One,8 (4), Apr 26.

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