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个人简介

学习经历 1980~1985,天津医学院卫生系 医学学士 1985~1988,天津医学院流行病学专业 医学硕士 2005~2008,南开大学环境科学与工程学院 理学博士 2009~2010,美国加州大学伯克利分校 访问学者 工作经历 2018~今,天津医科大学,博士生导师,院长 2012~今,天津医科大学劳动卫生与环境卫生学系 博士生导师,系主任 2001~2012,天津医科大学劳动卫生教研室 博士生导师,系主任 2000~今,天津医科大学公共卫生学院 教授 1995~2000,天津医科大学公共卫生学院 副教授 1990~1995,天津医学院公共卫生学院 讲师 1988~1990,天津医学院卫生系 助教 获奖情况 1.天津市科学技术进步二等奖,空气污染物与多器官疾病发病的关联研究,2015/12/16,2015JB-2-071-R5 2.天津市五一劳动奖章 2009/04 3.第十届天津市高等学校教学名师奖,2016/12 4.天津医科大学科技创新优秀指导教师荣誉称号

研究领域

1. 环境内分泌干扰物(EDCs)和持久性有机污染物(POPs)的健康影响 2. 大气污染健康影响的队列研究和机制探索

近期论文

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Shan A#, Li M, Li X, Li Y, Yan M, Xian P, Chang Y, Chen X*,Tang NJ. BDE-47 decreases progesterone levels in BeWo cells by interfering with mitochondrial functions and genes related to cholesterol transport. Chem Res Toxicol. 2019 Feb 4. doi: 10.1021/acs.chemrestox.8b00312. [Epub ahead of print]. Xu H#, Li PH#, Barrow TM, Colicino E, Li C, Song R, Liu H,Tang NJ, Liu S, Guo L*, Byun HM. Obesity as an effect modifier of the association between menstrual abnormalities and hypertension in young adult women: Results from Project ELEFANT. PLoS One. 2018 Nov 28; 13(11):e0207929. Guo L#*, Peng C#, Xu H#, Wilson A, Li PH, Wang H, Liu H, Shen L, Chen X, Qi X,Tang NJ, Barrow TM, Byun HM. Age at menarche and prevention of hypertension through lifestyle in young Chinese adult women: result from project ELEFANT. BMC Womens Health. 2018 Nov 9; 18(1):182. Barrow TM#, Peng C, Wilson A, Wang H, Liu H, Shen L,Tang NJ, Sae-Lee C, Li PH, Guo L*, Byun HM. Psychosocial stress is associated with benign breast disease in young Chinese women: results from Project ELEFANT. Breast Cancer Res Treat. 2019 Jan; 173(1):217-224. Zhang HJ#, Liu YN#, Xian P, Ma J, Sun YW, Chen JS, Chen X*,Tang NJ*. Maternal exposure to TCDD during gestation advanced sensory-motor development, but induced impairments of spatial learning and memory in adult male rat offspring. Chemosphere. 2018 Dec; 212:678-686. Xi Chen, Xue Wang, Jia-ju Huang, Li-wen Zhang, Feng-ju Song, Hong-jun Mao,Ke-xin Chen, Jie Chen, Ya-min Liu, Guo-hong Jiang, Guang-hui Dong, Zhi-peng Bai,Nai-jun Tang*. Nonmalignant respiratory mortality and long-term exposure to PM10 and SO2: A 12-year cohort study in northern China Environmental Pollution 231 (2017) 761-767 Li C#,Liu JC#,Xiao X,Chen X,Yue S,Yu H,Tian FS*,Tang NJ*. Psychological distress and type 2 diabetes mellitus: a 4-year policemen cohort study in China.BMJ Open. 2017 Jan 27; 7(1):e014235. Chen X#,Zhang LW#, Huang JJ, Song FJ, Zhang LP, Qian ZM, Trevathan E, Mao HJ, Han B, Vaughn M, Chen KX, Liu YM, Chen J, Zhao BX, Jiang GH, Gu Q, Bai ZP, Dong GH*, Tang NJ*. Long-term exposure to urban air pollution and lung cancer mortality: A 12-year cohort study in Northern China.Sci Total Environ. 2016 Nov 15; 571:855-61. Li C#,Xing JJ#,Shan AQ,Leng L,Liu JC,Yue S,Yu H,Chen X,Tian FS*,Tang NJ*. Increased risk of nonalcoholic fatty liver disease with occupational stress in Chinese policemen: A 4-year cohort study,Medicine (Baltimore). 2016 Nov; 95(46):e5359. Leng L#, Li J#, Luo XM, Kim JY, Li YM, Guo XM, Chen X, Yang QY, Li G*,Tang NJ*. Polychlorinated biphenyls and breast cancer: A congener-specific meta-analysis. Environ Int. 2016 Mar; 88:133-41. Yu H#,Liu JC#,Fan YJ,Li C,Zhang LX,Chen X,Yue S,Lu WL,Yang XL,Tang NJ*. Association between occupational stressors and type 2 diabetes among Chinese police officers: a 4-year follow-up study in Tianjin, China.Int Arch Occup Environ Health. 2016 Feb; 89(2):277-88. Ma J#, Chen X#, Liu Y, Xie Q, Sun Y, Chen J, Leng L, Yan H, Zhao B*,Tang N*.Ancestral TCDD exposure promotes epigenetic transgenerational inheritance of imprinted gene Igf2: Methylation status and DNMTs. Toxicol Appl Pharmacol. 2015 Dec 1; 289(2):193-202. Bao J, Zeng XW, Qin XD, Lee YL, Chen X, Jin YH,Tang NJ*, Dong GH*.Phthalate Metabolites in Urine Samples from School Children in Taipei, Taiwan. Arch Environ Contam Toxicol. 2015 Aug; 69(2):202-7. Chen X, Leng L, Yu H, Yang XL, Dong GH, Yue S, Chen JS,Tang NJ*.Psychological distress and dyslipidemia in chinese police officers: a 4-year follow-up study in Tianjin, China. J Occup Environ Med. 2015 Apr; 57(4):400-5. Chen X, Chen JS, Zhang L, Li JG, Yao L, Self SG, Sun X*,Tang NJ*. Levels of PCDDs, PCDFs and dl-PCBs in the blood of childbearing-aged women living in the vicinity of a chemical plant in Tianjin: A primary study.Chemosphere. 2015 Jan; 118:1-4. Zhang LW#, Chen X#, Xue XD, Sun M, Han B, Li CP, Ma J, Yu H, Sun ZR, Zhao LJ, Zhao BX, Liu YM, Chen J, Wang PP, Bai ZP*,Tang NJ*.Long-term exposure to high particulate matter pollution and cardiovascular mortality: A 12-year cohort study in four cities in northern China. Environ Int. 2014 Jan; 62:41-7. Yu ZR, Ning Y, Yu H,Tang NJ*.A HPLC-Q-TOF-MS-based urinary metabolomic approach to identification of potential biomarkers of metabolic syndrome. J Huazhong Univ Sci Technolog Med Sci. 2014 Apr; 34(2): 276-83. Leng L#, Chen X#, Li CP, Luo XY, Tang NJ*. 2,3,7,8-Tetrachlorodibezo-p-dioxin exposure and prostate cancer: a meta-analysis of cohort studies. Public Health. 2014 Mar; 128(3): 207-13. Chen X, Zhou QH, Leng L, Chen X, Sun ZR,Tang NJ*. Effects of Di(n-butyl) and Monobutyl Phthalate on Steroidogenesis Pathways in the Murine Leydig Tumor Cell Line MLTC-1. Environ Toxicol Pharmacol. 2013 Sep; 36(2): 332-8. Chen X, Liu YN, Zhou QH, Leng L, Chang Y,Tang NJ*. Effects of Low Concentrations of Di-(2-ethylhexyl) and Mono-(2-ethylhexyl) Phthalate on Steroidogenesis Pathways and Apoptosis in the Murine Leydig Tumor Cell Line MLTC-1. Biomed Environ Sci. 2013 Dec; 26(12): 986-9.

学术兼职

中华预防医学会 环境卫生学分会委员会常务委员 中华预防医学会 劳动卫生与职业病学分会委员 中华预防医学会 卫生毒理学分会委员 国家自然基金委医学部 二审专家/函审专家 河北/广东/湖北/天津等省市科研立项/奖励 评审专家 国家医师资格考试公共卫生类别试题开发专家委员会委员,聘期至2019年12月 天津市预防医学会 劳动卫生与职业病学分会副主任委员 天津市预防医学会 理事会理事 美国毒理学会会员(SOT) 国际职业卫生委员会会员(ICOH) 九三学社天津市第十一届委员会文化教育委员会委员 九三学社天津医科大学支社主任委员 天津市十二届、十三届政协委员 天津市人民检察院 人民监督员 《中华预防医学》 《中国公共卫生》 《中国工业医学》 《天津医药》 《职业与健康》等杂志编委 Environmental Science & Technology, Science of Total Environment, Chemosphere, Scientific Report, Proteomics, PLoS ONE, British Journal of Dermatology, Biomedical and Environmental Sciences,Environmental Toxicology and Pharmacology, Molecular and Cellular Biochemistry, Oncotarget等国际期刊审稿人。

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