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个人简介

博士,天津医科大学教授,博士生导师,天津市心脏学会流行病分会副主任委员,天津医科大学特聘专家。近几年来获得特聘专家启动基金及国家自然科学基金。在Plos Med, Alzheimer Dementia, Diabetes Care, Neurology, Diabetologia, Int J Cancer以及Nuerobiol Aging, Gerontology,Clinical Nutrition, Nueroigmaing等国际学术期刊上发表SCI论文80余篇,论文总引用次数2800余次,H-Index=24。 学习经历 2005~2008年,瑞典卡洛林斯卡研究院,博士学位 1987~1990年,天津医科大学卫生系,硕士学位 1982~1987年,天津医科大学卫生系,学士学位 获奖情况 2008年获得瑞典糖尿病协会办法的“最佳临床糖尿病论文答辩”奖 策略性研究规划-流行病学青年学者奖, 2010-2011

研究领域

主要研究方向是老年病流行病学及营养流行病学。

近期论文

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1.Xu WL#*,Pedersen NL, Keller L, Kalpouzos G, Wang HX, Graff C, Winblad B, Bäckman L, Fratiglioni L.HHEX_23 AA genotype exacerbateseffect of diabetes on dementia and Alzheimer disease: a population-based longitudinal study. PLoS Med, 2015 Jul 14;12(7):e1001853. 2.Xu WL#, Zhang H, Paillard-Borg S, Zhu H, Qi X, Debora R. Overweight and obesity among Chinese adults:role of adiposity indicators and age. Obesity Facts, 2016;9:17-28. 3.Shakersain B#*, Santoni G, Irving GF, Fratiglioni L, Xu WL*. Prudent diet may attenuate the adverse effect of the Western diet on cognitive decline, Alzheimers Dement, 2016;12(2):100-109. 4.Shakersain B#*, Santoni G, Irving GF, Fratiglioni L, Xu WL*. Nutritional status and survival among old adults: an 11-year population-based longitudinal study. Eur J Clin Nutr, 2016;70(3):320-325. 5.Pimouguet C#*, Rizzuto D, Schön P, Shakersain B, Angleman S, Lagergren M, Fratiglioni L,Xu WL*.Impact of living alone on institutionalization and mortality: a population-based longitudinal study. Eur J Public Health, 2016;26(1):182-7. 6.Pimouguet C#*, Rizzuto D, Fastbom J, Lagergren M, Fratiglioni L,Xu WL*.Influence of incipient dementia on hospitalizations due to primary care sensitive conditions: a population-based cohort study.J Alzheimers Dis, 2016;52(1):213-22. 7.Marseglia A#*, Fratiglioni L, Laukka EJ, Santoni G, Pedersen NL, Bäckman L,Xu WL*.Early Cognitive Deficits in Type 2 Diabetes: A Population-Based Study. J Alzheimers Dis, 2016;53(3):1069-78. 8.Pimouguet C#*, Rizzuto D, Lagergren M, Fratiglioni L,Xu WL*. Living alone and unplanned hospitalizations among older adults: A population-based longitudinal study. Eur J Public Health, 2017;27(2):251-6. 9.Welmer AK#*, Rizzuto D, Parker MG,Xu WL*. Impact of tooth loss on walking speed decline over time in older adults: a population-based cohort study. Aging Clin Exp Res, 2017; 29(4): 793–800. 10.Marseglia A#*, Dahl Aslan AK, Fratiglioni L, Santoni G, Pedersen NL,Xu WL*. Cognitive trajectories in prediabetes and diabetes: a population-based cohort study. J Gerontol A Biol Sci Med Sci, 2018;73(3):400-06. 11.Shakersain B#*, Rizzuto D,Larsson SC,Irving GF, Fratiglioni L, Xu WL*. Identifying a dietary pattern index that predicts preserved cognitive function in a Nordic country: a population-based cohort study. Nutrients, 2018;10:229. 12.Shakersain B#*, Rizzuto D, Wang HX, Irving GF, Fratiglioni L, Xu WL*.An active lifestyle reinforces the effect of healthy diet on cognitive decline. Nutrients, 2018;10,1297. 13.Dintica C#*, Rizzuto D, Marseglia A, Kalpouzos G, Welmer AK, Wårdh I, Bäckman L,Xu WL*. Tooth loss is associated with accelerated cognitive decline and volumetric brain differences: a population-based study. Neurobiol Aging, 2018;67:23-30. doi: 10.1016/j.neurobiolaging.2018.03.003. Epub 2018 Mar 9. 14.Bao C#*, Petersen NL, Yang R, Marseglia A, Wang Y, Qi X,Xu WL*.Diabetes in midlife and risk of cancer in later life: a nationwide twin study. Int J cancer, 2018;143 (4):793-800. 15.Marseglia A#*, Fratiglioni L, Kalpouzos G,Bäckman L,Xu WL*. Prediabetes and uncontrolled diabetes accelerate cognitive decline and the accumulation of brain vascular lesions. Alzheimers Dement, 2018 Aug 13. pii:S1552-5260(18)33249-7. 16.Marseglia A#*, Wang HX, Rizzuto D, Fratiglioni L,Xu WL*. Participating in mental, social, and physical leisure activities and having a rich social network reduce the incidence of diabetes-related dementia in a cohort of Swedish older adults. Diabetes Care, 2019;42:232-239. 17.Marseglia A#*,Xu WL*, Fratiglioni L, Fabbri C, Berendsen A, Bialecka-Debek A, Jennings A, Gillings R,Meunier N, Caumon E,Fairweather-Tait S,Pietruszka B,Cornelia L, De Groot PGM,Santoro A,Franceschi C.Effect of the NU-AGE Diet on Cognitive Functioning in Older Adults: a Randomized Controlled Trial. Front Physiol, 2018;9:349. 18.Bao C#*, Yang R, Xu W, Song R, Qi X,Xu WL*.Overweight in midlife and risk of cancer in later life: a nationwide Swedish twin study. Int J Cancer, 2019;144:2128-2134. 19.Dintica C#*, Marseglia A, Rizzuto D, Wang R, Seubert J,Arfanakis K,Bennett DA,Xu WL*.Impaired olfaction is associated with cognitive decline and neurodegeneration in the brain. Neurology, 2019; 12;92:e700-e709. 20.Prinelli F#*, Fratiglioni L, Musicco M, Johansson I, Adorni F,Shakersain B, Rizzuto D,Xu WL*.The impact of nutrient-based dietary patterns on cognitive decline among Swedish older adults. Clinical Nutrition (In press). DOI: https://doi.org/10.1016/j.clnu.2018.12.012

学术兼职

天津市心脏学会流行病分会副主任委员 天津市预防医学会流行病学分会会员

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