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个人简介

教育背景 2009-2014年,博士后,癌症与细胞生物学,辛辛那提大学,俄亥俄,美国 2008-2009年,博士后,分子生物学,中科院北京动物所,北京 2003-2008年,理学博士,生物物理专业,武汉大学生命科学学院,湖北 1999-2003年,理学学士,生物化学专业, 曲阜师范大学生命科学学院,山东 工作经历 2014年- 教授,博士生导师,遗传学系学,天津医科大学 荣誉奖励 2016年,天津市创新人才推进计划,青年项目 2019年,天津市杰出青年

研究领域

衰老生物学和端粒生物学

近期论文

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Zhang, M.M., Wang, B., Li, T.F., Liu, R., Xiao, Y.N., Li, G., Liu, Q., Geng,X., Price, C.M., Liu, Y.*, Wang,F.*,(2019), Mammalian CST averts replication failure by preventing G-quadruplex accumulation, Nucleic Acids. Res., 2019, Jun 4;47(10) 5243-5259 Rui Liu#, Jing Liu#, Shuqing Wang#, Yinsong Wang, Tao Zhang, Yang liu*, Xin Geng*, Feng Wang*, (2019)Combined treatment with emodin and a telomerase inhibitor induces significant telomere damage/dysfunction and cell death. Cell Death and Disease, 2019, Jul 11;10(7):527 Zhou Z, Wang L, Ge F, Gong P, Wang H, Wang F, Chen L, Liu L*.(2018) Pold3 is required for genomic stability and telomere integrity in embryonic stem cells and meiosis.Nucleic Acids. Res., 2018, 20;46(7):3468-3486 Yuan J#, Liu Y#, Wang J, Zhao Y, Li K, Jing Y, Zhang X, Liu Q, Geng X, Li G, Wang F*. (2018)Long-term Persistent Organic Pollutants Exposure Induced Telomere Dysfunction and Senescence-Associated Secretary Phenotype. J Gerontol A, 9;73(8) 1027-1035 Zheng XH, Nie X, Fang Y, Zhang Z, Xiao Y, Mao Z, Liu H, Ren J, Wang F, Xia L, Huang J, Zhao Y.*(2017) A Cisplatin Derivative Tetra-Pt(bpy) as an Oncotherapeutic Agent for Targeting ALT Cancer. J Natl Cancer Inst. 2017 1;109(10). Wang F*, Steward J, Carolyn PM*. (2014) Human CST Abundance Determines Recovery from Diverse Forms of DNA Damage and Replication Stress. Cell Cycle; 15;13(22):3488-3498 Kasbek,C., Wang,F., Price,C.M*. (2013) Human TEN1 maintains telomere integrity and functions in genome-wide replication restart. Journal of Biological Chemistry; 288(42): 30139-50 Wang, F.#, Tang, M.L., Zeng, Z.X., Wu. R.Y., Xue, Y., Hao, Y.H., Pang, D.W., Zhao, Y., Tan, Z*. (2012) Telomere- and telomerase-interacting protein that unfolds telomere G-quadruplex and promotes telomere extension in mammalian cells. Proc Natl Acad Sci U S A 109: 20413-20418 Wang, F., Stewart, J.A., Kasbek, C., Zhao, Y., Wright, W.E., Price, C.M*. (2012) Human CST has independent functions during telomere duplex replication and C-strand fill-in. Cell Rep. 2:1096-1103 Stewart, J.A.#, Wang, F.#, Chaiken, M.F., Kasbek, C., Chastain, P.D., Wright, W.E., Price, C.M.* (2012) Human CST promotes telomere duplex replication and general replication restart after fork stalling. EMBO J. 31:3537-3549 Stewart, J.A., Chaiken, M.F., Wang, F., Price, C.M.* (2012) Maintaining the end: Roles of telomere proteins in end-protection, telomere replication and length regulation. Mutation Research. 730:12-19 Wang, F., Zhao, Y., Hao, Y., Tan, Z. (2008) Identification of low-abundance alternatively spliced mRNA variants by exon exclusive reverse transcriptase polymerase chain reaction. Anal Biochem 383: 307-310 Kan, ZY.#, Lin, Y.#, Wang, F.#, Zhuang, X.Y., Zhao, Y., Pang, D.W., Hao, Y.H., Tan, Z. (2007) G-quadruplex formation in human telomeric (TTAGGG)4 sequence with complementary strand in close vicinity under molecularly crowded condition. Nucleic Acids. Res. 35: 3646-3653

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