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教育背景 2004.08-2008.02 英国 贝尔法斯特女王大学 生物医学博士 2000.08-2003.07 南开大学 生物化学与分子 生物学硕士 1996.09-2000.07 南开大学 生物化学与分子 生物学学士 工作经历 2012.07-至今 天津医科大学 基础医学院教授 2008.03-2012.06 美国宾夕法尼亚大学遗传系博士后研究员 2003.08-2004.07 南开大学 医学院实验技术人员 荣誉奖励 天津市特聘教授 天津市“131”创新型人才培养工程第一层次 天津市用三年时间引进千名高层次人才计划

研究领域

哺乳动物发育和肿瘤

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1、Li X, Ruan X, Zhang P, Yu Y, Gao M, Yuan S, Zhao Z, Yang J, Zhao L*. (2017) TBX3 promotes proliferation of papillary thyroid carcinoma cells through facilitating PRC2-mediated p57KIP2 repression. Oncogene. 37(21):2773-2792 2、Chen H, Zheng B, Liang C, Zhao L, Zhang Y, Pan H, Ji W, Gong X, Wang H, Chang J*.(2017) Near-infrared persistent luminescence phosphors ZnGa2O4:Cr3+ as an accurately tracker to photothermal therapy in vivo for visual treatment. Mater Sci Eng C Mater Biol Appl. 79:372-381. 3、 Zheng B, Wang H, Pan H, Liang C, Ji W, Zhao L, Chen H, Gong X, Wu X, Chang J*. (2017) Near-Infrared light triggered upconversion optogenetic nanosystem for cancer therapy. ACS Nano. 11(12):11898-907 4、Trowe MO, Zhao L*, Weiss AC, Christoffels V, Epstein DJ, Kispert A (2013)Inhibition of Sox2-dependent activation of Shh in the ventral diencephalon by Tbx3 is required for formation of the neurohypophysis. Development. 140(11):2299-309.(*共同第一作者) 5、Zhao L, Zevallos S. E, Rizzoti K, Jeong Y, Lovell-Badge R, and Epstein D.J. (2012) Disruption of Sonic hedgehog expression in the hypothalamus causes Septo-Optic Dysplasia. Dev Cell 22(3):585-96 6、Zhao L, Li G, and Zhou G.Q. (2009) SOX9 directly binds CREB as a novel synergism with the PKA pathway in BMP-2-induced osteochondrogenic differentiation. J Bone Miner Res. 24(5):826-36 7、Zhao L, Li.G, Chan K.M, Wang Y, and Tang P.F. (2009) Comparison of multipotent differentiation potentials of murine primary bone marrow stromal cells and mesenchymal stem cell line C3H10T1/2. Calcif Tissue Int. 84(1):56-64 8、Zhao Y, Bell D, Smith L.R, Zhao L, Devine A.B, McHenry E.M, Nicholls D.P and McDermott B.J. (2006) Differential expression of components of the cardiomyocyte adrenomedullin/ intermedin receptor system following blood pressure reduction in nitric oxide-deficient hypertension. J Pharmacol Exp The 316(3): 1269-81. 9、Yang S, Zhao L, Yang J, Chai D.G, Zhang M, Zhang J, Ji D, and Zhu T. (2007) δEF1 represses BMP-2-induced differentiation of C2C12 myoblast into osteoblast lineage. J.Biomed Sci 14(5):663-79 10、Zhao L, Yang S, Zhou G.Q, Yang J, Ji D, Sabatakos G and Zhu T. (2006) Downregulation of cAMP-dependent protein kinase inhibitor γ is required for BMP-2-induced osteoblastic differentiation. Int J Biochem Cell Biol 38(12): 2064-2073.

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