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个人简介

教育背景 1999/9 - 2003/7,南开大学,生物科学,学士 2003/9 - 2008/6,南开大学,微生物学,博士 工作经历 2016/12至今,天津医科大学,基础医学院生化系,教授 2011/10 -2016/12,天津医科大学,基础医学院生化系,副教授 2010/8 - 2011/9,北京大学医学部,基础医学院病理系,讲师 2008/7 - 2010/7,北京大学医学部,基础医学院生化系,博士后 荣誉奖励 1.2017年9月,天津市第四批创新人才推进计划——青年科技优秀人才 2.2017年9月,天津市131第一层次人才 3.2017年2月,天津市第二批青年拔尖人才

研究领域

医学表观遗传学

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1.Dawei Huo, Hao Chen, Yiming Cheng, Xin Song, Kai Zhang, Mulin Jun Li , Chenghao Xuan*. JMJD6 modulates DNA damage response through downregulating H4K16ac independently of its enzymatic activity (2019). Cell Death & Differentiation. 影响因子:8.086. 2.Yang Duan, Dawei Huo, Jie Gao, Heng Wu, Zheng Ye, Zhe Liu, Kai Zhang, Lin Shan, Xing Zhou, Yue Wang, Dongxue Su, Xiang Ding, Lei Shi, Yan Wang, Yongfeng Shang*, and Chenghao Xuan*. Ubiquitin Ligase RNF20/40 Facilitates Spindle Assembly and Promotes Breast Carcinogenesis through Stabilizing Motor Protein Eg5 (2016). Nature Communications 7: 12648. 影响因子:12.124. 3.Yang Duan, Xue Wu, Qiang Zhao, Jie Gao, Dawei Huo, Xinhua Liu, Zheng Ye, Xu Dong, Zheng Fu, Yongfeng Shang, and Chenghao Xuan*. DOT1L Promotes Angiogenesis through Cooperative Regulation of VEGFR2 with ETS-1 (2016). Oncotarget 7(43):69674-69687. 影响因子:5.168. 4.Chenghao Xuan*, Qian Wang, Xiao Han, Yang Duan, Lifang Li, Lei Shi, Yan Wang, Lin Shan, Zhi Yao, Yongfeng Shang*. RBB, a novel transcription repressor, represses the transcription of HDM2 oncogene (2013). Oncogene 32: 3711–3721. 影响因子:8.559. 5.Chenghao Xuan, Wentao Qiao, Jinmin Gao, Min Liu, Xihui Zhang, Youjia Cao, Qimin Chen, Yunqi Geng, Jun Zhou*. Regulation of microtubule assembly and stability by the transactivator of transcription of Jembrana disease virus (2007). The Journal of Biological Chemistry 282: 28800-6. 影响因子:5.581. 6.Chenghao Xuan#, Wentao Qiao#, Jian Li, Guoyuan Peng, Min Liu, Qimin Chen, Jun Zhou, Yunqi Geng*. BTat, a trans-acting regulatory protein, contributes to bovine immunodeficiency virus-induced apoptosis (2008). Cellular Microbiology 10: 31-40. 影响因子:5.598. 7.Dandan Huang, Xianfu Yi, Shijie Zhang, Zhanye Zheng, Panwen Wang, Chenghao Xuan, Pak Chung Sham, Junwen Wang, Mulin Jun Li*. GWAS4D: multidimensional analysis of context-specific regulatory variant for human complex diseases and traits (2018). Nucleic Acids Research 46: W114-W120. 8.Mulin Jun Li, Jian Zhang, Qian Liang, Chenghao Xuan, Jiexing Wu, Peng Jiang, Wei Li, Yun Zhu, Panwen Wang, Daniel Fernandez, Yujun Shen, Yiwen Chen, Jean-Pierre A. Kocher, Ying Yu, Pak Chung Sham, Junwen Wang*, Jun S. Liu*, X. Shirley Liu*. Exploring genetic associations with ceRNA regulation in the human genome (2017). Nucleic Acids Research (1): 1-13. 9.Lin Shan, Xing Zhou, Xinhua Liu, Yue Wang, Dongxue Su, Yongqiang Hou, Na Yu, Chao Yang, Beibei Liu, Jie Gao, Yang Duan, Jianguo Yang, Wanjin Li, Jing Liang, Luyang Sun, Kexin Chen, Chenghao Xuan, Lei Shi, Yan Wang, Yongfeng Shang*. FOXK2 Elicits Massive Transcription Repression and Suppresses the Hypoxic Response and Breast Cancer Carcinogenesis (2016). Cancer Cell (30):1-15. 10.Wenzhe Si, Wei Huang, Yu Zheng, Yang Yang, Xujun Liu, Lin Shan, Xing Zhou, Yue Wang, Dongxue Su, Jie Gao, Ruorong Yan, Xiao Han, Wanjin Li, Lin He, Lei Shi, Chenghao Xuan, Jing Liang, Luyang Sun, Yan Wang*, Yongfeng Shang*. Dysfunction of the Reciprocal Feedback Loop between GATA3- and ZEB2-Nucleated Repression Programs Contributes to Breast Cancer metastasis (2015). Cancer Cell (27):822-836.

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