个人简介
教育背景
2002/9-2004/7 北京大学医学预科（八年制本博连读）
2004/9-2007/7 北京大学医学部基础医学专业获医学学士学位
2007/9-2010/7 北京大学医学部基础医学院生化与分子生物学系 获理学博士学位
工作经历
2016/12-今 天津医科大学基础医学卓越研究中心PI
2014/12-今 天津医科大学基础医学院，教授，博导
2011/9-2014/12 天津医科大学基础医学院，副教授
2010/8-2011/7 美国国立卫生研究院癌症研究所，博士后
荣誉奖励
以第3完成人身份获得国家自然科学二等奖（国家科技部，乳腺癌发生发展的表观遗传机制）
近期论文
查看导师新发文章
（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）
(1)Dongxue Su#, Shuai Ma#, Lin Shan, Yue Wang, Yuejiao Wang, Cheng Cao, Beibei Liu, Chao Yang, Liyong Wang, Shanshan Tian, Xiang Ding, Xinhua Liu, Na Yu, Nan Song, Ling Liu, Shangda Yang, Qi Zhang, Fuquan Yang, Kai Zhang, Lei Shi* (2018). Ubiquitin-specific protease 7 sustains DNA damage response and promotes cervical carcinogenesis. JOURNAL OF CLINICAL INVESTIGATION, 2018, 128:10.
(2)Shangda Yang#, Ling Liu#, Cheng Cao, Nan Song, Yuejiao Wang, Shuai Ma, Qi Zhang, Na Yu, Xiang Ding, Fuquan Yang, Shanshan Tian, Kai Zhang, Tao Sun, Jie Yang, Zhi Yao, Shaoyuan Wu, Lei Shi* (2018).USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization. NATURE COMMUNICATIONS, 2018, 9.
(3)Xin Li#, Nan Song#, Ling Liu, Xinhua liu, Xiang Ding, Xin Song, Shangda Yang, Lin Shan, Xing Zhou, Dongxue Su, Yue Wang, Qi Zhang, Cheng Cao, Shuai Ma, Na Yu, Fuquan Yang, Yan Wang, Zhi Yao, Yongfeng Shang*, Lei Shi* (2017). USP9X Regulates Centrosome Duplication and Promotes Breast Carcinogenesis. Nature Communications, 2017, 8:14866. DOI: 10.1038/ncomms14866.
(4)Qian Wang#, Shuai Ma#, Nan Song, Xin Li, Ling Liu, Shangda Yang, Xiang Ding, Lin Shan, Xing Zhou, Dongxue Su, Yue Wang, Qi Zhang, Xinhua Liu, Na Yu, Kai Zhang, Yongfeng Shang, Zhi Yao*, and Lei Shi* (2016). Stabilization of Histone Demethylase PHF8 by USP7 Promotes Breast Carcinogenesis. The Journal of Clinical Investigation 126:2205–2220.
(5)Xin Li#, Ling Liu#, Shangda Yang, Nan Song, Xing Zhou, Jie Gao, Na Yu, Lin Shan, Qian Wang, Jing Liang, Chenghao Xuan, Yan Wang, Yongfeng Shang*, and Lei Shi* (2014). Histone Demethylase KDM5B Is a Key Regulator of Genome Stability. PNAS 111:7096-7101.
(6)Lin Shan, Xin Li, Ling Liu, Xiang Ding, Qian Wang, Yu Zheng, Yang Duan, Chenghao Xuan, Yan Wang, Fuquan Yang, Yongfeng Shang, and Lei Shi* (2014). GATA3 Cooperates with PARP1 to Regulate CCND1 Transcription through Modulating Histone H1 Incorporation. Oncogene 33:3205-3216.
(7)Wenshu Ge, Yunsong Liu, Tong Chen, Xiao Zhang, LongweiLv, ChanyuanJin, Yong Jiang, Lei Shi*, Yongsheng Zhou* (2014). The epigenetic promotion of osteogenic differentiation of human adipose-derived stem cells by the genetic and chemical blockade of histone demethylase LSD1. Biomaterials 35:6015-6025.
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