个人简介
教育背景
2010/07－2013/07，北京大学，基础医学院生理系，博士
2005/09－2010/07，北京大学，基础医学院，基础医学八年制专业，医学学士
工作经历
2017/12至今，天津医科大学，生理学与病理生理学系，副教授
2013/07-2017/12，天津医科大学，生理学与病理生理学系，讲师
2011/09—2012/10，美国俄克拉荷马大学健康医学中心（OUHSC），分子生物学专业，联合培养博士生
荣誉奖励
2018年9月入选天津市创新人才推进计划青年科技优秀人才
2017年入选天津市“131”创新型人才培养工程三层次
近期论文
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1. Li B#, He J#, Lv H, Liu Y, Lv X, Zhang C, Zhu Y*, Ai D* c-Abl regulates YAPY357 phosphorylation to activate endothelial atherogenic responses to disturbed flow. J Clin Invest. 2019 Feb 11.[Epub ahead of print]
2. He J#, Bao Q#, Zhang Y, Liu M, Lv H, Liu Y, Yao L, Li B, Zhang C, He S, Zhai G, Zhu Y, Liu X, Zhang K, Wang XJ, Zou MH, Zhu Y, Ai D* Yes-Associated Protein Promotes Angiogenesis via Signal Transducer and Activator of Transcription 3 in Endothelial Cells. Circ Res. 2018; 122, 591-605
3. Peng L#, Sun B#, Liu M, Huang J, Liu Y, Xie Z, He J, Chen L, Wang D, Zhu Y, Zhang X, Ai D* Plasma metabolic profile reveals PGF2alpha protecting against non-proliferative diabetic retinopathy in patients with type 2 diabetes. Biochem Biophys Res Commun.2018; 496, 1276-1283
4. Ding Y#, Li Y#, Zhang X, He J, Lu D, Fang X, Wang Y, Wang J, Zhang Y, Qiao X, Gan LM, Chen C*, Zhu Y* Soluble epoxide hydrolase activation by S-nitrosation contributes to cardiac ischemia-reperfusion injury. J Mol Cell Cardiol. 2017; 110, 70-79
5. Liu Y, Fang X, Zhang X, Huang J, He J, Peng L, Ye C, Wang Y, Xue F, Ai D, Li D, Zhu Y (2017) Metabolic profiling of murine plasma reveals eicosapentaenoic acid metabolites protecting against endothelial activation and atherosclerosis. Br J Pharmacol.2017 [Epub ahead of print]
6. He J, Bao Q, Yan M, Liang J, Zhu Y, Wang C*, Ai D*. The role of hippo/yes-associated protein signalling in vascular remodelling associated with cardiovascular disease. Br J Pharmacol. 2017 [Epub ahead of print] (Review)
7. Wang C#, Liu W#, Yao L#, Zhang X, Ye C, Jiang H, He J, Zhu Y, Ai D. Hydroxyeicosapentaenoic acids and epoxyeicosatetraenoic acids attenuate early occurrence of nonalcoholic fatty liver disease. Br J Pharmacol. 2017;174:2358-2372
8. Yao L#, Wang C#, Zhang X, Peng L, Liu W, Liu Y, He J, Jiang C, Ai D*, Zhu Y*. Hyperhomocysteinemia activates the aryl hydrocarbon receptor/cd36 pathway to promote hepatic steatosis in mice. Hepatology. 2016;64:92-105
9. Xue S#, Wang J#, Zhang X, Shi Y, Li B, Bao Q, Pang W, Ai D, Zhu Y, He J*. Endothelial atp-binding cassette g1 in mouse endothelium protects against hemodynamic-induced atherosclerosis. Biochem Biophys Res Commun. 2016;477:247-254
10. He J#, Wang C#, Zhu Y, Ai D*. Soluble epoxide hydrolase: A potential target for metabolic diseases.Journal of diabetes. 2016;8:305-313 (Review)
11. Xue S#, He J#, Zhang X, Liu Y, Xue F, Wang C, Ai D*, Zhu Y*. Metabolomic analysis revealed the role of DNA methylation in the balance of arachidonic acid metabolism and endothelial activation. Biochim Biophys Acta. 2015;1851:1317-1326
12. Wang Q#, Huo L#, He J, Ding W, Su H, Tian D, Welch C, Hammock B, Ai D*, Zhu Y*. Soluble epoxide hydrolase is involved in the development of atherosclerosis and arterial neointima formation by regulating smooth muscle cell migration. Am J Physiol Heart Circ Physiol. 2015;309(11):H1894-903.
13. Wang J#, Li H#, He J, Li B, Bao Q, Zhang X, Lv Z, Zhang Y, Han J, Ai D, Zhu Y*. 20-hydroxyeicosatetraenoic acid involved in endothelial activation and thrombosis. Am J Physiol Heart Circ Physiol. 2015;308:H1359-1367
14. He J, Zhou Y, Xing J, Wang Q, Zhu H, Zhu Y*, Zou MH*. Liver kinase b1 is required for thromboxane receptor-dependent nuclear factor-kappab activation and inflammatory responses. Arterioscler Thromb Vasc Biol. 2013;33:1297-1305
15. Fu C, He J, Li C, Shyy JY, Zhu Y*. Cholesterol increases adhesion of monocytes to endothelium by moving adhesion molecules out of caveolae. Biochim Biophys Acta. 2010;1801:702-710
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